(A) Stress echocardiography. During physical or pharmacological stress, cineloops of the heart are captured and digitally stored. In order to detect subtle wall motion abnormalities, cineloops of the same view (here: apical four-chamber view) from different stress stages are displayed in a synchronized manner (adapted replay speed) side-by-side. In this example, apical four-chamber view loops at rest (top left), at 30mcg/kg/min dobutamine infusion (top right), and 40mcg/kg/min dobutamine infusion and additional atropine (peak stress; bottom left), and at recovery are displayed. Note different heart rates in the right lower corner of each loop. (B) Survival of 5375 patients undergoing treadmill exercise stress echocardiography according to results of the test: normal; presence of scar; presence of ischaemia; presence of scar and ischaemia combined. Reproduced with permission from Marwick TH, Case C, Vasey C, et al. Prediction of mortality by exercise echocardiography. A strategy for combination with the Duke treadmill score. Circulation 2001; 103: 2566–71.