(A) Calculation of LV volume and ejection fraction by the modified Simpson‘s rule. The ventricle is manually delineated. The method assumes rotational symmetry. Thus, the ventricular volume can be assumed to be equal the added volumes of the cylinders which fit into the delineated border. If systolic and diastolic volumes are estimated in this way, stroke volume and ejection fraction can be calculated. (B) Example of left ventricular biplane volume and ejection calculation, with normal values. Reproduced with permission from Lang R, Bierig M, Devereux R, et al. Recommendations for Chamber Quantification. A report from the American Society of Echocardiography’s Nomenclature and Standards Committee, the Task Force on Chamber Quantification, and the European Association of Echocardiography. Eur J Echocardiogr 2006; 7: 79–108.