(A) Risk of all-cause mortality based on hazard ratio in CRT-D vs. CRT-P patients. Forest plot of studies with data on all-cause mortality using hazard ratios. The analysis included 18 studies comparing 36 421 CRT-D patients with 26 473 CRT-P patients. The HR was 0.74 (95% CI: 0.66–0.82). (B) Risk of all-cause mortality based on adjusted hazard ratio in CRT-D vs. CRT-P patients. Forest plot of studies with data on all-cause mortality using adjusted hazard ratios. The analysis included 22 studies comparing 40 434 CRT-D patients with 33 054 CRT-P patients. The aHR was 0.85 (95% CI: 0.76–0.94). (C) Risk of all-cause mortality based on PSM in CRT-D vs. CRT-P patients. Forest plot of studies with data on all-cause mortality using PSM. The analysis included eight studies comparing 13 220 CRT-D patients with 13 220 CRT-P patients. The HR was 0.83 (95% CI: 0.80–0.87). aHR, adjusted hazard ratio; CI, confidence interval; CRT-D, cardiac resynchronization therapy with defibrillator; CRT-P, cardiac resynchronization therapy with pacemaker.