Efficacy endpoints in patients with metabolic syndrome*, but without diabetes at baseline. *Diagnosis of metabolic syndrome requires the presence of three or more of the following five risk factors using these baseline criteria TG ≥ 150 mg/dL; low HDL-cholestrol <40 mg/dL if male and <50 mg/dL if female; fasting glucose ≥100 mg/dL OR on drug therapy for elevated glucose; blood pressure systolic ≥130 mmHg and/or diastolic ≥85 mmHg OR on antihypertensive therapy with medical history of hypertension; and a waist circumferences ≥35 inches (88 cm) for all women and Asian, Hispanic, or Latino men, and waist circumferences ≥40 inches (102 cm) for all other men.