Hazards of primary and secondary end-points during follow-up in (A) adult and (B) paediatric patients, comparing congenital heart disease patients with all other patients as a single category. Analyses for the primary outcome of mortality were stratified by time at 1 year due to non-proportional hazards of the exposure variable. Insufficient events were present in the paediatric cohort to evaluate association with mortality: after 1 year. All results are derived from Cox proportional hazards models, where patients were censored at the time of outcome occurrence, mortality, transplant, or last recorded date of follow-up.