Correlation matrix for the melting temperature (T_m), net increase in LMW as measured by SE-UPLC (D_LMW), net increase in fragmentation as measured by NR-CGE (D_NR_Frag), and net increase in fragmentation as measured by R-CGE (D_R_Frag) of trastuzumab biosimilar in different formulation conditions. For fragmentation measurement, trastuzumab biosimilar formulations at 5 mg/mL were stressed at 40 °C for 2 weeks and subsequently subjected to analytical testing to determine the relative change in fragmentation value. Density ellipse with an alpha value of 0.95 was shown to guide the reading on the distribution of data. Formulations consisting of the same buffer are labeled using the same color in the correlation (blue: Na-acetate; red: Na-succinate; green: Histidine-HCl; purple: Na-phosphate). Heatmap indicates the level of correlation between variables with their Pearson correlation coefficients shown inside.