Figure 5.
Multiple linear regression showed significant correlations between Braak tau stage and zinc and iron in the locus coeruleus; sodium in the cerebellum; and sodium, magnesium, iron, copper, zinc, and selenium in the motor cortex. It also showed correlations between age and zinc in the substantia nigra; magnesium, potassium, and selenium in the hippocampus; and copper in the medulla.

Correlations of regional metal concentrations with tau Braak stage and age. This figure shows significant correlations between tau Braak stage or age and regional metals in combined cohort, as determined by multiple linear regression (P < .05).

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