Fig. 4
Age-adjusted hazard ratios (HR) for gastroesophageal cancers according to Body Mass Index (BMI). Curves are plotted for both sexes combined, men, and women for esophageal adenocarcinoma (A), pooled esophagus and cardia adenocarcinoma (B), gastric cardia adenocarcinoma (C), gastric adenocarcinoma (D), and non-cardia gastric adenocarcinoma (E) with 95% confidence intervals, allowing for non-linear effects modelled using restricted cubic splines. The reference BMI was fitted as a spline with HR fixed as 1·0 is 22 kg/m2.