Dynamics of plasma viral load during the study. A, Viral load measured using standard techniques: The percentage of participants reaching HIV-1 RNA <50 copies/mL at each time point is shown. B, Residual viremia: Individual determinations and medians for each study group are shown. Half of the lower limit of quantification (LLOQ) of this ultrasensitive quantification (0.33 copy/mL) was used to represent samples below LLOQ in the graph (open symbols). The gray dotted lines indicate the 50 copies/mL and the 0.33 copy/mL levels. Abbreviations: 2DR, 2-drug regimen (dolutegravir plus lamivudine); 3DR, 3-drug regimen (dolutegravir plus emtricitabine/tenofovir alafenamide); HIV-1, human immunodeficiency virus type 1; pVL, plasma viral load.