Changes from baseline in soluble inflammatory biomarkers during the study. Median and interquartile range are presented. Abbreviations: 2DR, 2-drug regimen (dolutegravir plus lamivudine); 3DR, 3-drug regimen (dolutegravir plus emtricitabine/tenofovir alafenamide); BL, baseline; CRP, C-reactive protein; DD, D-dimer; FABP2, fatty acid–binding protein 2; IL-6, interleukin 6; IP-10, interferon-γ–induced protein 10; sCD14, soluble CD14; TRAIL, tumor necrosis factor–related apoptosis-inducing ligand.