Figure 2.
LncRNA profiles in human not in labor (NIL) and in labor (IL) myometrium. LncRNA sequencing was done in 2 groups: NIL (n = 5) and IL (n = 4). (A) The heat map in 2 groups. (B) The volcano plot of lncRNAs upregulated and downregulated in 2 groups: 205 lncRNAs were upregulated (P < .05) and 291 lncRNAs (P < .05) were downregulated. (C) 9 known upregulated lncRNAs were chosen: GAS5, PELATON, H19, SNHG16, LUCAT1, CYTOR, SOCS3-DT, MYG1-AS1, and LNCOG. Real-time PCR was done to validate the profile of these lncRNAs in NIL (n = 13) and IL (n = 11) myometrium. All the 9 lncRNAs were verified to be upregulated in IL myometrium. *P < .05.