Correlations between Multimodal MRICIs and Each Symptom Dimension in Schizophrenia. Scatterplots of the Left Panels Depict the Spearman Correlation between Multimodal MRICI Scores and One Symptom Dimension in FE (Dark-Colored) and NFE (Light-Colored) Schizophrenia (Permutation Test, P < .05, Bonferroni Correction). The 3 Brain Maps on the Right Display the Contribution Weights of 3 Neuroimaging Metrics (Permutation Test, P < .05)

Abbreviations: MRICI = MRI composite indicator; FE = first-episode schizophrenia patients; NFE = non-first-episode schizophrenia patients; CCC = canonical correlation coefficient; GMV = gray matter volume; FA = fractional anisotropy; FCS = functional connectivity strength; Pd = positive symptom dimension; Nd = negative symptom dimension; Cd = cognitive symptom dimension; Ed = excitative symptom dimension; Dd = depressive symptom dimension