Figure 4.
Prediction-corrected VPC showing the observed 2.5th, 50th and 97.5th percentiles (lines) and corresponding 95% CIs from the combined cfu and TTP PD model. Left: predicted cfu over time after the start of treatment, and percentage of predicted and observed censored observations in the lower panel. Right: predicted TTP over time after the start of treatment, and percentage of predicted and observed censored observations in the lower panel. The grey horizontal lines represent the censoring limits.

Prediction-corrected VPC showing the observed 2.5th, 50th and 97.5th percentiles (lines) and corresponding 95% CIs from the combined cfu and TTP PD model. Left: predicted cfu over time after the start of treatment, and percentage of predicted and observed censored observations in the lower panel. Right: predicted TTP over time after the start of treatment, and percentage of predicted and observed censored observations in the lower panel. The grey horizontal lines represent the censoring limits.

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