Boxplot with superimposed violin plot for laboratory marker values at the initial visit in which the decision to de-escalate was made. Patients are grouped based on the need for re-escalation at follow-up and were compared via Mann–Whitney U comparison. After Bonferroni correction, the initial CRP was significantly higher (7.5 vs. 1.4 mg/L) in patients that required re-escalation at follow-up (P < .001).