Regulation of aromatase activity, between premenopausal and postmenopausal females in Sc (A) (pre-, n = 7; post-, n = 10) and Om (B) (pre-, n = 6; post-, n = 6) preadipocyte cells, by cortisol (F) and insulin (500 nm). Activity is expressed as mean ± sem pmol/mg protein·h. Statistical analysis, using an unpaired t test, compared pre- vs. postmenopausal females (*, P < 0.05; **, P < 0.001).