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Book cover for Oxford Textbook of Heart Failure (1 edn) Oxford Textbook of Heart Failure (1 edn)
Disclaimer
Oxford University Press makes no representation, express or implied, that the drug dosages in this book are correct. Readers must therefore always … More Oxford University Press makes no representation, express or implied, that the drug dosages in this book are correct. Readers must therefore always check the product information and clinical procedures with the most up to date published product information and data sheets provided by the manufacturers and the most recent codes of conduct and safety regulations. The authors and the publishers do not accept responsibility or legal liability for any errors in the text or for the misuse or misapplication of material in this work. Except where otherwise stated, drug dosages and recommendations are for the non-pregnant adult who is not breastfeeding.
AA

aldosterone antagonist

ACE

angiotensin converting enzyme

ACEi

angiotensin converting enzyme inhibitor

ACHD

adult congenital heart disease

ACR

acute cellular rejection

ACS

acute coronary syndrome

ACTH

adrenocorticotrophic hormone

ACTIV

acute and chronic therapeutic impact of a vasopressin antagonist

ADH

anti-diuretic hormone

AF

atrial fibrillation

AHA

American Heart Association

AHeFT

American Heart Failure Trial

AHF

acute heart failure

AIF

apoptosis inducing factor

AIV

anterior interventricular vein

AKI

acute kidney injury

ALS

advanced life support

AMI

acute myocardial infarction

AMPK

AMP-activated protein kinase

AMR

antibody-mediated rejection

ANP

atrial natriuretic peptide

AP

action potential

APD

action potential duration

APT

amiodarone pulmonary toxicity

AR

aortic regurgitation

ARB

angiotensin receptor blocker

ARVC

arrhythmogenic right ventricular cardiomyopathy

ARVD

atherosclerotic renovascular disease

AS

aortic stenosis

ASD

atrial septal defects

ASTRAL

Angioplasty and Stenting for Renal Artery Lesions

AT

anaerobic threshold

ATLAS

Assessment of Treatment with Lisinopril and Survival

AUC

area under the curve

AV

aortic valve; atrioventricular

AVID

Antiarrhythmics Versus Implantable Defibrillator

AVP

arginine vasopressin

BB

β-blocker

BiPAP

bilevel positive airway pressure

BIPS

Bezafibrate Infarction Prevention Study

BMI

body mass index

BNP

B-type natriuretic peptide

BSA

body surface area

CABG

coronary artery bypass grafting

CACT

carnitine/acylcarnitine translocase

CAD

coronary artery disease

CAM

cell adhesion molecules

CASH

Cardiac Arrest Study of Hamburg

CAV

cardiac allograft vasculopathy

CCTGA

congenitally corrected transposition of the great arteries

CDG

congenital disorders of glycosylation

CHD

coronary heart disease

CHF

chronic heart failure

CHO

Chinese hamster ovary

CHS

Cardiovascular Health Study

CI

cardiac index

CIDS

Canadian Implantable Defibrillator Study

CK

creatine kinase

CKD

chronic kidney disease

CMR

cardiac magnetic resonance

CNP

C-type natriuretic peptide

CNS

central nervous system

CO

cardiac output

COMET

Carvedilol Or Metoprolol European Trial

CONSENSUS

Cooperative North Scandinavian Enalapril Survival Study

COPD

chronic obstructive pulmonary disease

CPAP

continuous positive airway pressure

CPET

cardiopulmonary metabolic exercise testing

CPG

Committee for Practice Guideline

CPR

cardiopulmonary resuscitation

CR

cardiac rehabilitation

CRP

C-reactive protein

CRT

cardiac resynchronization therapy

CS

coronary sinus

CSA

central sleep apnoea

CSD

cardiac support device

CVC

central venous cannulation

CVP

central venous pressure

DCCT

Diabetes Control and Complications Trial

DCM

dilated cardiomyopathy

DCT

distal convoluted tubule

DEFINITE

Defibrillators in Non-Ischemic Cardiomyopathy Treatment Evaluation

DFT

diastolic filling time

DIABHYCAR

Type 2 DIABetes, Hypertension, Cardiovascular, Events and Ramipril study

DINAMIT

Defibrillator in Acute Myocardial Infarction Trial

DM

diabetes mellitus

DMARD

disease-modifying antirheumatic drugs

DVT

deep venous thrombosis

EARTH

Endothelin A Receptor Antagonist Trial in Heart

EBCT

electron beam CT

ECHOES

Echocardiographic Heart of England Screening Study

EDV

end-diastolic volume

EF

ejection fraction

ELISA

enzyme-linked immunosorbent assay

ELITE

Evaluation of Losartan in The Elderly

EPC

endothelial progenitor cells

EPHESUS

Eplerenone Post-acute MI Heart failure Efficacy and Survival Study

ER

endoplasmic reticulum

ERO

effective regurgitant orifice

ERS

European Respiratory Society

ERT

enzyme replacement therapy

ESA

erythropoiesis-stimulating agents

ESC

European Society of Cardiology

ESICM

European Society of Intensive Care Medicine

ESR

erythrocyte sedimentation rate

ESS

Epworth sleepiness score

ESV

end-systolic volume

ETF

electron transfer flavoprotein

ETF

electron transfer flavoprotein

EVEREST

efficacy of vasopressin antagonism in decompensated heart failure

FADD

Fas-associated death domain

FAOD

fatty acid oxidation disorders

FBC

full blood count

FDA

Food and Drug Administration

FDG

fluoro-d-glucose

FGF

fibroblast growth factor

FMR

functional mitral regurgitation

FRC

functional residual capacity

FVC

forced vital capacity

GCV

great cardiac vein

GFR

glomerular filtration rate

GJ

gap junctions

GPRD

General Practice Research Database

GSD

glycogen storage disorders

GSF

Gold Standards Framework

HAART

highly active antiretroviral therapy

HASTE

half-Fourier acquisition single-shot turbo spin-echo

HBI

home-based intervention

HEAAL

Heart failure Endpoint evaluation of Angiotensin II Antagonist Losartan

HeFNEF

heart failure with normal (preserved) ejection fraction

HELLP

haemolysis, elevated liver enzymes, low platelets

HF

heart failure

HFNS

heart failure nurse specialists

HFSA

Heart Failure Society of America

HFSS

Heart Failure Survival Score

HH

hereditary haemochromatosis

HLA

human leucocyte antigen

HLS

hypoplastic left heart syndrome

HMR

heart to mediastinal ratio

HOT

Hypertension Optimal Treatment Study

HRQL

health-related quality of life

HSCT

haematopoietic stem cell transplantation

IABP

intra-aortic balloon pump

ICD

implantable cardioverter defibrillator

ICU

intensive care unit

IDCM

idiopathic dilated cardiomyopathy

IE

infective endocarditis

IHD

ischaemic heart disease

INR

international normalized ratio

IPF

idiopathic pulmonary fibrosis

IRIS

Immediate Risk Stratification Improves Survival

ISHLT

International Society of Heart and Lung Transplantation

IVC

inferior vena cava

JVP

jugular venous pressure

KCCQ

Kansas City Cardiomyopathy Questionnaire

LBBB

left bundle branch block

LCFA

long-chain fatty acids

LCHAD

long-chain hydratase and hydroxyacyl-CoA dehydrogenase

LGE

late gadolinium enhancement

LHON

Leber hereditary optic neuropathy

LTOT

long-term oxygen therapy

LV

left ventricle/left ventricular

LVAD

left ventricular assist device

LVD

left ventricular dysfunction

LVDD

left ventricular diastolic dysfunction

LVEDP

left ventricular end-diastolic pressure

LVEF

left ventricular ejection fraction

LVESV

left ventricular end-systolic volumes

LVESVI

left ventricular end-systolic volume index

LVH

left ventricular hypertrophy

LVMI

left ventricular mass index

LVSD

left ventricular systolic dysfunction

MAD

multiple acyl-CoA dehydrogenases

MADIT

Multicenter Automatic Defibrillator Trial

MDC

Metoprolol in Dilated Cardiomyopathy

MDCT

multidetector row CT

MDRD

Modification of Diet in Renal Disease

MELAS

mitochondrial encephalomyopathy with lactic acidosis and stroke-like episodes

METEOR

Multicentre Evaluation of Tolvaptan Effect on Remodelling

MI

myocardial infarction

MIBI

methoxyisobutylisonitrile

MLHFQ

Minnesota Living with Heart Failure Questionnaire

MLP

muscle LIM protein

MPS

myocardial perfusion scintigraphy

MS

mitral stenosis

MSNA

muscle sympathetic nerve activity

MTP

mitochondrial trifunctional protein

MUGA

multiple gated acquisition

MUSTT

Multicenter UnSustained Tachycardia Trial

MVV

maximum voluntary ventilation

NAD

nicotinamide adenine dinucleotide

NFAT

nuclear factor of activated T-cells

NHLBI

National Heart, Lung and Blood Institute

NHYA

New York Heart Association

NNH

number needed to harm

NP

natriuretic peptides

NPR

natriuretic peptide receptor

NPV

negative predictive value

NRF

nuclear respiratory factors

NSAID

nonsteroidal anti-inflammatory drug

NYHA

New York Heart Association

OMT

optimal medical therapy

OSA

obstructive sleep apnoea

PAC

pulmonary artery catheter

PAFC

pulmonary artery flotation catheter

PAH

pulmonary arterial hypertension

PCI

percutaneous coronary intervention

PCR

polymerase chain reaction

PCWP

pulmonary capillary wedge pressure

PD

peritoneal dialysis

PDGF

platelet-derived growth factor

PEA

pulseless electrical activity

PEEP

positive end-expiratory pressure

PEF

peak expiratory flow

PET

positron emission tomography

PH

pulmonary hypertension

PIV

posterior interventricular vein

PLE

protein-losing enteropathy

PMC

percutaneous mitral commissurotomy

PND

paroxysmal nocturnal dyspnoea

PPAR

peroxisomal proliferator-activated receptor

PSA

prostate specific antigen

PSIR

phase-sensitive inversion recovery

PTLD

post-transplant lymphoproliferative disease

PVAD

paracorporeal ventricular assist device

PVI

pulmonary vein isolation

PVLV

posterior vein of the left ventricle

PVR

pulmonary vascular resistance

PWV

pulse wave velocity

QALY

quality-adjusted life year

QoL

quality of life

RA

rheumatoid arthritis; right atrium/atrial

RAAS

renin–angiotensin–aldosterone system

RALES

Randomized Aldactone Evaluation Study

RANKL

RANK ligand

RANTES

regulated upon activation, normal T cell expressed and secreted

RAS

renal artery stenosis

RBBB

right bundle branch block

RCT

randomized controlled trial

RDI

respiratory disturbance index

RDW

red cell distribution width

REM

rapid eye movement

RESOLVD

Randomized Evaluation of Strategies for Left Ventricular Dysfunction

RHC

right heart catheterization

RNVG

radionuclide ventriculography

ROC

receiver operating curve

ROS

reactive oxygen species

RQ

respiratory quotient

RR

relative risk

RRR

relative risk reduction

RRT

renal replacement therapy

RV

right ventricle/ventricular

RVEDP

right ventricular end diastolic pressure

RWMA

regional wall motion abnormalities

RXR

retinoid X receptors

SAVE

Survival and Ventricular Enlargement

SCD

sudden cardiac death

SCDHeFT

Sudden Cardiac Death in Heart Failure Trial

SDB

sleep-disordered breathing

SHF

systolic heart failure

SHFM

Seattle Heart Failure Model

SICM

scanning ion-conductance microscopy

SIGN

Scottish Intercollegiate Guidelines Network

SLE

systemic lupus erythematosus

SOLVD

Studies of Left Ventricular Dysfunction

SoV

sinus of Valsalva

SPECT

single photon emission CT

SPICE

Study of Patients Intolerant of Converting Enzyme

SR

sarcoplasmic reticulum; sinus rhythm

SSFP

steady-state free precession

STICH

Surgical Treatment for Ischemic Heart

STIR

short-tau inversion recovery

SU

sulphonylurea drug

SVC

superior vena cava

SVR

systemic vascular resistance

TAPSE

tricuspid annular plane systolic excursion

TARA

Trial of Atorvastatin in Rheumatoid Arthritis

TAT

transverse-axial tubular

TAVI

transcatheter aortic valve implantation

TCA

tricarboxylic acid

TDI

tissue Doppler imaging

TGF

transforming growth factor

TLC

total lung capacity

TLR

Toll-like receptors

TMS

tandem mass spectrometry

TNF

tumour necrosis factor

TOE

transoesophageal echocardiogram

TOR

target of rapamycin

TR

tricuspid regurgitation

TREAT

Trial to Reduce Cardiovascular Events with Aranesp Therapy

TS

tricuspid stenosis

TSE

turbo-spin echo

TTC

triphenyltetrazolium chloride

TZD

thiazolidenedione drug (glitazone)

UA

unstable angina

UGDP

Universities Group Diabetes Project

UKPDS

United Kingdom Prospective Diabetes Survey

UPR

unfolded protein response

VAD

ventricular assist device

VC

vital capacity

VE

minute ventilation

VEGF

vascular endothelial growth factor

VF

ventricular fibrillation

VHD

valvular heart disease

VHeFT

Vasodilator Heart Failure Trial

VPB

ventricular premature beats

VRS

ventricular restoration surgery

VSD

ventricular septal defect; ventricular systolic dysfunction

VT

ventricular tachyarrhythmia; ventricular tachycardia

VTI

velocity time integral

WASH

Warfarin-Aspirin Study in Heart

WCC

white cell count

WRF

worsening renal function

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