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Letter
Sociodemographic, lifestyle, and medical factors associated with calculated free testosterone concentrations in men: individual participant data meta-analyses
Nick Narinx and others
Dear editor, We appreciate the comments from Bons et al. regarding our study on sociodemographic, lifestyle and medical factors associated with calculated free testosterone concentrations in men. We acknowledge the concerns raised about the use of different immunoassays for sex hormone-binding ...
Research Article
Impact of hydrocortisone versus prednisone therapy on post-surgical recovery in patients with endogenous hypercortisolism: a prospective cohort study
Rashi Sandooja and others
Objective Glucocorticoid withdrawal syndrome (GWS) may develop in patients following successful surgery for endogenous hypercortisolism. Effective strategies to minimize GWS and improve quality of life (QoL) are currently lacking. We aimed to determine the impact of hydrocortisone versus prednisone ...
Research Article
Genetic predisposition to adiposity and type 2 diabetes: the role of lifestyle, and phenotypic adiposity
Mengrong Zhang and others
Aims Genetic predisposition to adiposity is associated with type 2 diabetes (T2D), even in the absence of phenotypic adiposity (obesity and central obesity). We aimed to quantify the overall contribution of obesity and modifiable lifestyle factors to the association between genetic predisposition ...
Research Article
Conservatively managed non-functioning pituitary macroadenomas – cohort study from the UK Non-functioning Pituitary Adenoma Consortium
Athanasios Fountas and others
Objective Surveillance is often adopted for asymptomatic non-functioning pituitary macroadenomas (macroNFPAs). Due to low quality evidence, uncertainty remains on optimal frequency of imaging/biochemical monitoring and indications for surgery. We assessed the natural history and outcomes of ...
Brief Report
Primary Adrenal Insufficiency in Patients with CPOX Gene Mutations
Elif Kelestemur and others
Background Harderoporphyria arises from biallelic CPOX gene mutations, leading to coproporphyrinogen oxidase deficiency in the inner mitochondrial membrane. The impact of CPOX gene mutations on adrenal function remains poorly understood. Objective Characterizing primary adrenal insufficiency (PAI) ...
Research Article
Non-recurrent mutations and copy number changes predominate pituitary adenoma genomes
Dipika R Mohan and others
Objective Pituitary adenomas are common neoplasms. Our current understanding of the molecular basis of pituitary adenoma formation is incomplete. Routine implementation of targeted genomics has enabled the discovery of rare, potentially clinically actionable events. Methods We used a cancer-focused ...
Brief Report
Sex differences between mid-life glycaemic traits and brain volume at age 70: A population-based study
Nasri Fatih and others
Higher HbA1c in mid-to-later life has been associated with smaller whole brain volume (WBV) in older women but not men. We explored whether this association was replicated using different markers of (a) glycaemic health (fasting glucose, insulin resistance (HOMA2-IR), and β-cell function (HOMA-%B) ...
Review Article
Sexual dimorphism in benign adrenocortical tumours
Onnicha Suntornlohanakul and others
Benign adrenocortical tumours are the most common adrenal neoplasms. Evidence over the past few decades has highlighted sex differences in their prevalence, clinical characteristics, and treatment outcomes. Cortisol-producing adenomas causing either Cushing’s syndrome, particularly those with ...
Research Article
Impact of 24-week concurrent training on bone parameters and plasma levels of osteoglycin and sclerostin in young, sedentary adults: secondary analyses from the ACTIBATE randomized controlled trial
Juan J Martin-Olmedo and others
Objective To examine the effects of 24-week moderate- (MOD-EX) and vigorous-intensity concurrent training (VIG-EX) on bone parameters and plasma levels of osteoglycin and sclerostin and their interplay with body composition and cardiometabolic risk factors in young, sedentary men and women. Design ...
Research Article
How ready are endocrine scientists to share retrospective clinical data for research: a perspective from the European Network for the Study of Adrenal Tumors
Antoan Stefan Sojat and others
Objective Individual patients' data sharing requires interoperability, security, ethical, and legal compliance. The aim was to assess the landscape and sharing capacities between endocrine researchers. Design A standardized survey (SurveyMonkey®) with 67 questions was sent to European Network for ...
Impact Factor
5.3
5 year Impact Factor
5.7

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