Advancements in toxicological risk assessment: integrating Ferguson’s principle, computational models, and drug safety guidelines, a comprehensive framework for improving risk assessment and resource management in toxicology

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Radiation-induced esophagitis and lung injury during esophageal squamous cell cancer therapy is correlated to tumor gene expression phenotype

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In vitro investigation of the toxicological mechanisms of Fingolimod (S)-phosphate in HEPG2 cells

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The effect of 50 Hz magnetic fields on cellular sensitivity of mouse spermatogenic cell lines to hydrogen peroxide

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Incorporating Metabolic Competence into High-Throughput Profiling Assays

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From Promise to Practice: Why HRMS Has Yet to Fully Revolutionize Forensic Toxicology

Dual inhibition of TGFβ2,3 is severely toxic, whereas selective inhibition of TGFβ1, 2, or 3 and dual inhibition of TGFβ1,2 is generally tolerated In mouse and cynomolgus monkey toxicology studies

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Dual inhibition of TGFβ2,3 is severely toxic, whereas selective inhibition of TGFβ1, 2, or 3 and dual inhibition of TGFβ1,2 is generally tolerated In mouse and cynomolgus monkey toxicology studies

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Lateral flow immunoassay for amatoxins detection in human urine compared to liquid chromatography-high-resolution tandem mass spectrometry

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Chaperone mediated autophagy modulates microglia polarization and inflammation via LAMP2A in ischemia induced spinal cord injury

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How diquat kills: Investigation of the toxicological profiles of diquat and bromide ion concentrations in serum by LC-MS/MS and capillary electrophoresis in a suicide case

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Benzene metabolites increase vascular permeability by activating heat shock proteins and Rho GTPases

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Of Hammers and Nails: Understanding Academic Challenges with “Context of Use” and “Fit for Purpose”

FTO-mediated m6A demethylation of KLF4 promotes the proliferation and collagen deposition of keloid fibroblasts

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Long-term exposure to silica nanoparticles induces cardiac hypertrophy through the pyroptosis pathway

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Oral exposure to di(2-ethylhexyl) phthalate (DEHP) alters the expression of GATA6, OCT4, and CDX2 in blastocysts and decreases the rate of implantation in a mouse model

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Oral fluid device performance in identifying amphetamine, methamphetamine, and cocaine use in Brazilian drivers

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Catechin designates individual and co-adjuvant antiproliferative effects with docetaxel in prostate cancer cell models

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In vitro seizure risk assessment using a microelectrode array and comparison with an in vivo rat study

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Quantification of daridorexant, lemborexant and suvorexant in whole blood using liquid chromatography-tandem mass spectrometry

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