Abstract
Enlargement of the pituitary gland and/or its surrounding structures on brain or sellar imaging is a frequent finding. The distinction between clinically relevant and incidental changes can be challenging. Further, the assumption that sellar lesions reflect a true neoplasm must be rigorously questioned to avoid inappropriate treatment or unnecessary surveillance plans. Here we review wide-ranging conditions that can mimic primary pituitary tumors. We outline a suggested approach to rational decision-making.
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© The Author(s) 2025. Published by Oxford University Press, the Society for Neuro-Oncology and the European Association of Neuro-Oncology.
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