MET-09 Prognosis prediction study of using Susceptibility-weighted imaging in metastatic brain tumors

Background and purpose: MRI is a very useful tool especially for metastatic brain tumor. It can grasp the status of treatment and progress of primary lesion. In this study, we investigated the prognosis by using SWI (Susceptibility-weighted imaging) or T2 *sequences in MRI. Materials and methods: The study includes 69 patients who took a surgical treatment at our hospital from March 2014 to June 2020. Grade ranged from 0 to 2, with 0 defined as high signal intratumor, 1 defined as within 10 dark spots, 2 as almost consists with dark spot intratumor. Results: The median age of the patients was 66 years and 38 males (55%). The primary tumors were lung cancer in 28 cases (40.7%), breast cancer in 12 cases (17.4%), gastrointestinal cancer in 11 cases (15.9%), kidney cancer in 5 cases (7.2%), and others in 13 cases (18.8%). The SWI or T2 star images showed that grade 0 was 23 cases (33%), grade 1 was 18 cases (26%), grade 2 was 28 cases (41%). There were 16 deaths in grade 0 (69.6%), 10 deaths in grade 1 (55.6%), 15 deaths in grade 2 (53.5%). Conclusions: In this study, there was no statistically significant difference in the SWI or T2*-positive group. However, there was a tendency for many long-term survivors in the SWI or T2*-positive group.