Developmental exposure to 1,4-dioxane, a volatile organic compound of emerging concern, induces immediate phenotypic, transcriptomic, and adult-onset neurodevelopmental effects

• Abstract
• Supplementary data

Exposure to phthalates enhances estrogen and beta-catenin signaling pathways, leading to endometrial hyperplasia in mice

• Abstract

4-Methylpyrazole-mediated inhibition of Cytochrome P450 2E1 protects renal epithelial cells, but not bladder cancer cells, from cisplatin toxicity

• Abstract
• Supplementary data

Cigarette butts: a source of toxicity and potential disruption of Pila virens antioxidant mechanisms

• Abstracts

Abnormal chenodexycholic acid metabolism programming promotes cartilage matrix degradation in male adult offspring rats induced by prenatal caffeine exposure

• Abstract

In vitro investigation of the toxicological mechanisms of Fingolimod (S)-phosphate in HEPG2 cells

• Abstract
• Supplementary data

Advancements in toxicological risk assessment: integrating Ferguson’s principle, computational models, and drug safety guidelines, a comprehensive framework for improving risk assessment and resource management in toxicology

• Abstract
• Supplementary data

Radiation-induced esophagitis and lung injury during esophageal squamous cell cancer therapy is correlated to tumor gene expression phenotype

• Abstract
• Supplementary data

The effect of 50 Hz magnetic fields on cellular sensitivity of mouse spermatogenic cell lines to hydrogen peroxide

• Abstract
• Supplementary data

Lateral flow immunoassay for amatoxins detection in human urine compared to liquid chromatography-high-resolution tandem mass spectrometry

• Abstract
• Supplementary data

Incorporating Metabolic Competence into High-Throughput Profiling Assays

• Abstract
• Supplementary data

From Promise to Practice: Why HRMS Has Yet to Fully Revolutionize Forensic Toxicology

Dual inhibition of TGFβ2,3 is severely toxic, whereas selective inhibition of TGFβ1, 2, or 3 and dual inhibition of TGFβ1,2 is generally tolerated In mouse and cynomolgus monkey toxicology studies

• Abstract
• Supplementary data

Dual inhibition of TGFβ2,3 is severely toxic, whereas selective inhibition of TGFβ1, 2, or 3 and dual inhibition of TGFβ1,2 is generally tolerated In mouse and cynomolgus monkey toxicology studies

• Abstract
• Supplementary data

Chaperone mediated autophagy modulates microglia polarization and inflammation via LAMP2A in ischemia induced spinal cord injury

• Abstract
• Supplementary data

Benzene metabolites increase vascular permeability by activating heat shock proteins and Rho GTPases

• Abstract
• Supplementary data

Of Hammers and Nails: Understanding Academic Challenges with “Context of Use” and “Fit for Purpose”

How diquat kills: Investigation of the toxicological profiles of diquat and bromide ion concentrations in serum by LC-MS/MS and capillary electrophoresis in a suicide case

• Abstract
• Supplementary data

FTO-mediated m6A demethylation of KLF4 promotes the proliferation and collagen deposition of keloid fibroblasts

• Abstract
• Supplementary data

Long-term exposure to silica nanoparticles induces cardiac hypertrophy through the pyroptosis pathway

• Abstract
• Supplementary data