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100 years

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The American Journal of Epidemiology (AJE) was founded in 1920, with the first issue published in January 1921. In the past 100 years, the Journal has gone through many changes, including changes in frequency of publication and even name (from American Journal of Hygiene to American Journal of Epidemiology in 1965). Through it all, one thing that has remained the same is our dedication to publishing timely, relevant, and impactful research on epidemiology and public health. In the coming year (and beyond!), the AJE will solidify its mission statement for the future and make updates to provide a better user experience and launch us into the next era. 

As William Welch noted in his introduction to the first issue of the Journal, “The history of public health administration and of preventive medicine exemplifies perhaps more strikingly than any other field the dependence of successful practice upon accurate knowledge.” We at the AJE are proud to have assisted in the publication and dissemination of that knowledge, and we are looking forward to the next 100 years. Please join us in our celebration!


Read the 100 years editorial in the January 2021 issue

100 years in a few slides

Trace the history of the AJE with important milestones and a selection of influential articles. Click here for easy access to the interactive timeline.

Interactive timeline preview (click to open in another tab): 100 years of the American Journal of Epidemiology

Video interviews

Listen to the authors of some of our highly cited articles to get further insight into the impact of their work.

The 100-Year Anniversary Symposium

Learn more about the rich history of the American Journal of Epidemiology with this video of AJE's 100-Year Anniversary Symposium, featuring presentations and a panel with Enrique F. Shisterman, Moyses Szklo, Jonathan M. Samet, Ana V. Diez Roux, and Mark Lipsitch.

Moving into the next 100 years together

As part of our move into the next 100 years of the AJE, we have streamlined our instructions to authors (ITA)! We had already significantly reduced the initial submission guidelines to make the process as simple as possible. Now we have reorganized and revamped the rest of the ITA to make it even easier to find answers to your questions (although you can always contact the editorial office). 

Our most cited papers

Discover the most cited articles of all times from the American Journal of Epidemiology.

Most cited

A Modified Poisson Regression Approach to Prospective Studies with Binary Data
Updating and Validating the Charlson Comorbidity Index and Score for Risk Adjustment in Hospital Discharge Abstracts Using Data From 6 Countries
REPRODUCIBILITY AND VALIDITY OF A SEMIQUANTITATIVE FOOD FREQUENCY QUESTIONNAIRE
Increased Prevalence of Sleep-Disordered Breathing in Adults
Multi-Ethnic Study of Atherosclerosis: Objectives and Design
THE ATHEROSCLEROSIS RISK IN COMMUNIT (ARIC) STUDY: DESIGN AND OBJECTIVES
Relaxing the Rule of Ten Events per Variable in Logistic and Cox Regression
TOTAL ENERGY INTAKE: IMPLICATIONS FOR EPIDEMIOLOGIC ANALYSES
Comparison of Sociodemographic and Health-Related Characteristics of UK Biobank Participants With Those of the General Population
Methods for Trend Estimation from Summarized Dose-Response Data, with Applications to Meta-Analysis
Simulation Study of Confounder-Selection Strategies
Constructing Inverse Probability Weights for Marginal Structural Models
Amount of Time Spent in Sedentary Behaviors in the United States, 2003–2004
A DATA-BASED APPROACH TO DIET QUESTIONNAIRE DESIGN AND TESTING
The Case-Crossover Design: A Method for Studying Transient Effects on the Risk of Acute Events
ESTIMABILITY AND ESTIMATION IN CASE-REFERENT STUDIES
Socioeconomic Inequalities in Depression: A Meta-Analysis
Statistical Analysis of Correlated Data Using Generalized Estimating Equations: An Orientation
A REVIEW OF GOODNESS OF FIT STATISTICS FOR USE IN THE DEVELOPMENT OF LOGISTIC REGRESSION MODELS
Estimating the Relative Risk in Cohort Studies and Clinical Trials of Common Outcomes
RESPIRATORY SYNCYTIAL VIRUS DISEASE IN INFANTS DESPITE PRIOR ADMINISTRATION OF ANTIGENIC INACTIVATED VACCINE
Using Big Data to Emulate a Target Trial When a Randomized Trial Is Not Available
THE EPIDEMIOLOGY OF APPENDICITIS AND APPENDECTOMY IN THE UNITED STATES
PHYSICAL ACTIVITY ASSESSMENT METHODOLOGY IN THE FIVE-CITY PROJECT
THE CONTRIBUTION OF THE SOCIAL ENVIRONMENT TO HOST RESISTANCE: THE FOURTH WADE HAMPTON FROST LECTURE
THE DIET AND 15-YEAR DEATH RATE IN THE SEVEN COUNTRIES STUDY
Evaluating Medication Effects Outside of Clinical Trials: New-User Designs
THE EFFICACY OF INFECTION SURVEILLANCE AND CONTROL PROGRAMS IN PREVENTING NOSOCOMIAL INFECTIONS IN US HOSPITALS
Immortal Time Bias in Pharmacoepidemiology
Incidence of Parkinson’s Disease: Variation by Age, Gender, and Race/Ethnicity
ESTIMATING THE POPULATION ATTRIBUTABLE RISK FOR MULTIPLE RISK FACTORS USING CASE-CONTROL DATA
THE MULTICENTER AIDS COHORT STUDY: RATIONALE, ORGANIZATION, AND SELECTED CHARACTERISTICS OF THE PARTICIPANTS
Meta-Analysis for Linear and Nonlinear Dose-Response Relations: Examples, an Evaluation of Approximations, and Software
Multivariable Mendelian Randomization: The Use of Pleiotropic Genetic Variants to Estimate Causal Effects
Competing Risk Regression Models for Epidemiologic Data
Limitations of the Odds Ratio in Gauging the Performance of a Diagnostic, Prognostic, or Screening Marker
ASSESSMENT OF HABITUAL PHYSICAL ACTIVITY BY A SEVEN-DAY RECALL IN A COMMUNITY SURVEY AND CONTROLLED EXPERIMENTS
Systematic Review of Type 1 and Type 2 Diabetes Mellitus and Risk of Fracture
THE ASSOCIATION OF SOCIAL RELATIONSHIPS AND ACTIVITIES WITH MORTALITY: PROSPECTIVE EVIDENCE FROM THE TECUMSEH COMMUNITY HEALTH STUDY
Geocoding and Monitoring of US Socioeconomic Inequalities in Mortality and Cancer Incidence: Does the Choice of Area-based Measure and Geographic Level Matter?: The Public Health Disparities Geocoding Project
Risk Factors for Alzheimer’s Disease: A Prospective Analysis from the Canadian Study of Health and Aging
A META-ANALYSIS OF PHYSICAL ACTIVITY IN THE PREVENTION OF CORONARY HEART DISEASE
VALIDATION OF QUESTIONNAIRE INFORMATION ON RISK FACTORS AND DISEASE OUTCOMES IN A PROSPECTIVE COHORT STUDY OF WOMEN
Characteristics Relating to Ovarian Cancer Risk: Collaborative Analysis of 12 US Case -Control Studies: II. Invasive Epithelial Ovarian Cancers in White Women
Efficient Design for Mendelian Randomization Studies: Subsample and 2-Sample Instrumental Variable Estimators
AN EPIDEMIOLOGIC STUDY OF ALTERED CLINICAL REACTIVITY TO RESPIRATORY SYNCYTIAL (RS) VIRUS INFECTION IN CHILDREN PREVIOUSLY VACCINATED WITH AN INACTIVATED RS VIRUS VACCINE
Incidence of and Risk Factors for Falls and Injurious Falls among the Community-dwelling Elderly
Time Lines of Infection and Disease in Human Influenza: A Review of Volunteer Challenge Studies
The Effect of Social Desirability and Social Approval on Self-Reports of Physical Activity
Skeletal Muscle Cutpoints Associated with Elevated Physical Disability Risk in Older Men and Women
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