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Orthotopic liver transplantation (OLT) represents the standard of care for patients with end-stage liver disease, acute liver failure, and certain types of liver-related malignancies such as hepatocellular carcinoma 1 . Although in the initial phase following OLT patient survival is mainly ...
Empty pelvis syndrome is identified as the single most frequent cause of major morbidity after pelvic exenteration. A syndrome pattern in the natural history of these complications is observed. Omentoplasty is confirmed as being a useful technique to mitigate these complications and biological meshes appear to significantly reduce exposure to reconstruction-related morbidity.
This prospective pan-European study found low morbidity and mortality rates, good pain relief, and improved quality of life after surgery for chronic pancreatitis and confirmed the need for earlier patient referral.
Adjuvant hyperthermic intraperitoneal chemotherapy (HIPEC) did not significantly improve the locoregional recurrence rate, disease free-survival, and overall survival in patients with locally advanced colon cancer. A significant reduction in locoregional recurrence was found after adjuvant HIPEC in patients with right-sided tumours, especially those with proven pT4 stage tumours. There was a measurable impact of adjuvant HIPEC on intraperitoneal disease recurrence, but this required a specific study population with sufficient a priori risk.
This 8-year retrospective audit investigates the incidence and characteristics of non-technical errors linked to patient death in the Australian Surgical cohort. The incidence of overall non-technical errors and non-technical errors by individual domains are reported plus statistically significant predictors of non-technical error occurrence identified. The results of this study demonstrate that the incidence of non-technical errors linked to patient death is high and highlights clear targets for future non-technical skill improvement efforts.
Our exploratory machine learning–based analysis of data from the CRASH-2 and CRASH-3 trials suggests that tranexamic acid should be administered as soon as possible within 2 h of injury to a broad range of trauma patients, regardless of vital signs. Of note, administration of tranexamic acid beyond 2 h after injury should be considered in patients with severe traumatic brain injury. Machine learning–based models can help explore heterogeneity in treatment effects and identify optimal treatment strategies without prior assumptions.
This RCT compared robotic-assisted transabdominal preperitoneal (R-TAPP) and conventional laparoscopic transabdominal preperitoneal (L-TAPP) inguinal hernia repair, demonstrating that R-TAPP was associated with reductions in surgical stress, complications, operating time, and hospital stay. These findings underscore the potential advantages of robotic surgery and its role in improving short-term outcomes in inguinal hernia repair.
The multinational prospective study SnapSBO evaluates the real-world impact of adherence to the WSES Bologna guidelines on adhesive small bowel obstruction outcomes. Across 70 centres in 20 countries, higher compliance correlates with reduced length of stay and improved patient outcomes, yet full adherence remains infrequent, particularly in operative cases. These findings highlight persistent evidence-to-practice gaps and underscore the need for targeted implementation strategies to enhance guideline adoption and optimize adhesive small bowel obstruction management.
This study sought to externally validate a model predicting 5-year recurrence-free and melanoma-specific survival. In a large independent cohort consisting of patients from the USA, Europe, and Israel, the model showed good performance, emphasizing its generalizability and robustness. Additionally, decision curve analysis showed a benefit of using the model.
The Endo-STAR framework breaks down endovascular interventions into their key component parts. It may be used to assist in developing future trial protocols, the standardization of infrainguinal endovascular interventions, the monitoring of adherence to the trial protocols, and as a standardized reporting guideline.
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