EHJ Dialogues

In this EHJ Dialogue, Prof. Ulrich Sigwart, the inventor of the coronary stent, shares the remarkable story behind one of cardiovascular medicine’s most transformative innovations. From its origins and current applications to its future potential, Prof. Sigwart offers a compelling perspective on the evolution of stenting in clinical care. He also reflects on why Switzerland was uniquely poised to become the birthplace of this breakthrough.

Moderated by Executive Editor Prof. Colin Berry and Editor in Chief Prof. Filippo Crea, this Dialogue provides insights into the past, present, and future of cardiovascular intervention.

In this EHJ Dialogue, Prof. Sanjit Jolly, Principal Investigator of the CLEAR-Colchicine trial, discusses the role of colchicine in cardiovascular disease, exploring its anti-inflammatory effects and potential therapeutic applications. Joining are Prof. François Roubille and Prof. Massimo Imazio, who provide additional insights into the clinical implications and evolving research on colchicine in cardiovascular medicine.

Moderated by Weekly Journal Scan Editors Profs. Carlo Patrono and Giovanna Liuzzo, along with Editor-in-Chief Prof. Filippo Crea, this conversation delves into the latest trial data, key takeaways for clinical practice, and future directions for anti-inflammatory strategies in cardiology.

In this EHJ Dialogue, leading researcher in cardiovascular science and Editor-in-Chief of Cardiovascular Research (CVR) Prof. Tomasz Guzik shares his expertise on the role of inflammation in hypertension, discusses the challenges AI presents for scientific publishing, and offers a preview of key innovations at the upcoming ESC Congress in Madrid. Additionally, he highlights his humanitarian work supporting cardiovascular health initiatives in Africa.

Moderated by EHJ Executive Editor Cecilia Linde and Editor-in-Chief Filippo Crea, this conversation offers valuable insights into the future of cardiovascular research, the evolving landscape of scientific publishing, and the impact of innovation on global healthcare.

In this EHJ Dialogue, Prof. Jane Somerville, a pioneer in congenital heart disease management, shares insights from her groundbreaking career. With congenital heart disease now affecting more adults than children, Prof. Somerville’s contributions have shaped the field and improved care for countless patients.

Moderated by Prof. John Deanfield and EHJ Editor-in-Chief Prof. Filippo Crea, this Dialogue explores the establishment of the world’s first dedicated ward for adolescents with congenital heart disease, the inaugural World Congress of Paediatric Cardiology in London, and the founding of The Somerville Foundation, supporting adults with congenital heart disease.
This conversation offers valuable perspectives on the evolution of congenital heart disease care and the impact of Prof. Somerville’s work.

In this special year-end EHJ Dialogue, EHJ editors and guests come together to discuss the most impactful advancements in cardiovascular medicine, as highlighted by the top EHJ papers of 2024.

Editor-in-Chief Filippo Crea is joined by EHJ Editors Lale Tokgozoglu, Margarita Brida, Cecilia Linde, and Susanna Price to reflect on key contributions that have shaped the field over the past year. Together, they explore their implications for clinical practice, emerging research directions, and the future of cardiovascular care. A thought-provoking discussion on the discoveries that defined 2024 and what lies ahead for cardiovascular medicine.

In this EHJ Dialogue, Prof. Luigi Fontana explores the transformative potential of targeted lifestyle interventions in modulating key metabolic and molecular pathways that influence aging and disease progression. This discussion extends beyond the cardiovascular system, highlighting how common chronic diseases across different organs and systems share a unified metabolic and molecular foundation, often shaped by unhealthy lifestyle choices.

Moderated by Prof. Raffaele De Caterina and EHJ Editor-in-Chief Prof. Filippo Crea, this Dialogue offers cutting-edge insights into shifting the focus from managing chronic diseases to fostering long-term health and resilience.

Weekly Journal Scan Editor Prof. Carlo Patrono takes us through the fascinating history, present applications, and future potential of aspirin in cardiovascular care.

Moderated by Executive Editor Prof. Lina Badimon and Editor in Chief Filippo Crea, this Dialogue offers invaluable insights into one of the most significant drugs in medical history.

In this EHJ Dialogue, Prof. Lars Wallentin shares insights from his extensive career in registries, trials and biomarkers spanning from ischaemic heart disease to atrial fibrillation.

Moderated by Executive Editor Prof. Peter Libby, and Editor-in-Chief Prof. Filippo Crea, this Dialogue offers a deep dive into the evolution of cardiovascular research, highlighting key discoveries, clinical implications, and future directions in the field.

In this EHJ Dialogue, Prof. Rory Collins shares insights from his extensive career in trials, meta-analyses, and epidemiology.

Moderated by Executive Editor Prof. Perry Elliott and Editor-in-Chief Prof. Filippo Crea, this conversation explores the evolution of large-scale studies, the challenges of translating data into practice, and the future of evidence-based medicine.

In this EHJ Dialogue, Prof. Deepak Bhatt shares his life story and explores the complexities and challenges in interpreting clinical trial data.

Moderated by Associate Editor Prof. Alberico Catapano and Editor-in-Chief Prof. Filippo Crea, this conversation explores the nuances of clinical research, the evolution of evidence-based medicine, and the critical thinking required to navigate and apply trial data effectively.

In this EHJ Dialogue, Nobel Laureate Prof. Lou Ignarro takes us on a fascinating journey from his early curiosity as a ten-year-old student to the pinnacle of scientific achievement: receiving the Nobel Prize.

Moderated by Executive Editor Prof. Lina Badimon and Editor-in-Chief Prof. Filippo Crea, this conversation delves into the critical role of endothelial dysfunction, its implications for cardiovascular health, and the future of nitric oxide research.

In this EHJ Dialogue, Prof. William McKenna delves into the captivating history of cardiomyopathies, tracing its remarkable journey from the pioneering days of ECG to the cutting-edge advances in genetic diagnostics.

Moderated by Deputy Editor Prof. John Cleland and Editor-in-Chief Prof. Filippo Crea, this conversation offers valuable insights into how historical milestones have shaped our current understanding and management of cardiomyopathies.

In this EHJ Dialogue, renowned heart failure expert Prof. Bertram Pitt discusses the past, present, and future of mineralocorticoid receptor antagonists, exploring key clinical trial outcomes and emerging therapeutic strategies.

Moderated by EHJ Executive Editor Prof. Cecilia Linde and Deputy Editor Prof. Johann Bauersachs, this conversation offers valuable perspectives for clinicians and researchers dedicated to advancing patient care in cardiovascular medicine.

In this EHJ Dialogue, Prof. Paul Ridker explores the role of inflammation in atherosclerosis, tracing the evolution from C-reactive protein (CRP) as a biomarker to the identification of therapeutic targets.

Moderated by Executive Editor Prof. Lina Badimon and Editor-in-Chief Prof. Filippo Crea, this insightful conversation delves into the latest research, clinical implications, and future directions in the field.

In this EHJ Dialogue, Prof. Eva Prescott highlights the vital role of women in cardiology and explores the challenges faced in developing impactful clinical Guidelines.

Moderated by Associate Editor Prof. Rasha Al-Lamee and Editor-in-Chief Prof. Filippo Crea, this insightful conversation delves into the evolving landscape of cardiology and the efforts to drive meaningful change in the field.

In this EHJ Dialogue, leading expert in COVID-19-related cardiovascular disease, Dr. Ziyad Al-Aly examines Long COVID that currently affects millions worldwide. He discusses the emerging challenges for cardiologists in managing the wave of COVID-19–related cardiovascular conditions and outlines the long-term implications for patient care and healthcare systems.

Moderated by Weekly Journal Scan Editors Prof. Giovanna Liuzzo and Prof. Massimo Volpe, this conversation provides valuable insights into the enduring impact of COVID-19 and the readiness of the medical community to address its long-term consequences.

In this EHJ Dialogue, Prof. Peter Schwartz shares his unique insights into the evolution of long QT syndrome, his pivotal role in its discovery, and the emerging promise of precision medicine for channelopathies.

Moderated by Executive Editor Prof. Perry Elliott and Editor-in-Chief Prof. Filippo Crea, this conversation offers invaluable perspectives on the past, present, and future of cardiac channelopathies.

In this EHJ Dialogue, Prof. Javed Butler focuses on SGLT2 in heart failure.

Moderated by Weekly Journal Scan Editor Prof. Carlo Patrono and Prof. Giovanna Liuzzo, Associate Editor Prof. Shelley Zieroth, and Editor-in-Chief Prof. Filippo Crea, this conversation offers valuable insights into future research perspectives.

In this EHJ Dialogue, Prof. Göran Hanssen explores the history of atherosclerosis, tracing key discoveries and advancements that have shaped our understanding of the disease.

Moderated by Executive Editor Prof. Peter Libby and Editor-in-Chief Prof. Filippo Crea, this engaging conversation delves into the evolution of research and its impact on cardiovascular medicine.

In this EHJ Dialogue, Prof. Valentin Fuster discusses the SECURE trial, presented at the ESC Congress 2022 and published in the New England Journal of Medicine, highlighting its key findings and clinical implications.

Moderated by Weekly Journal Scan Editors Prof. Giovanna Liuzzo, Prof. Carlo Patrono, and Prof. Daniela Pedicino, Associate Editor Michelle O'Donoghue, and Editor-in-Chief Prof. Filippo Crea, this conversation offers valuable insights into the study’s impact on cardiovascular care.

In this EHJ Dialogue, Prof. Gregory Lip discusses the ABC approach to the management of atrial fibrillation, outlining its key principles and clinical applications.

Moderated by Deputy Editor Prof. Felicita Andreotti and Editor-in-Chief Prof. Filippo Crea, , this conversation explores the latest advancements, practical considerations, and the evolving landscape of atrial fibrillation treatment.

In this EHJ Dialogue, Prof. George Bakris, Prof. Ernesto Schiffrin, and Prof. Francesco Paneni discuss therapeutic developments in the management of diabetic chronic kidney disease.

Moderated by Weekly Journal Scan Editor Prof. Massimo Volpe and Editor-in-Chief Prof. Filippo Crea, this conversation explores the evolving landscape of care, clinical challenges, and future directions in the field.

In this EHJ Dialogue, echocardiography pioneer Prof. Anthony DeMaria shares his remarkable journey in the field. He reflects on the inception of echocardiography, its evolution into a cornerstone of cardiovascular imaging, and the exciting prospects for its future.

Moderated by Prof. Chiara Bucciarelli-Ducci and EHJ Editor-in-Chief Prof. Filippo Crea.

In this EHJ Dialogue, Prof. Karen Sliwa shares her remarkable scientific journey studying heart failure and discusses cardiovascular diseases in Africa, highlighting both the challenges and opportunities in the field.

Moderated by Executive Editor Prof. Anne Tybjærg-Hansen and EHJ Editor-in-Chief Prof. Filippo Crea, this conversation provides valuable insights into global cardiovascular health and the future of research and care in diverse healthcare settings.

In this EHJ Dialogue, Prof. Silvia Priori explores the role of precision medicine in the prevention of sudden cardiac death, highlighting advances in genetic risk assessment, tailored interventions, and emerging therapeutic strategies.

Moderated by Executive Editor Prof. Perry Elliott and Editor-in-Chief Prof. Filippo Crea, this conversation delves into the latest research, clinical applications, and the future of personalized approaches in cardiovascular care.

In this EHJ Dialogue, Prof. Kazem Rahimi discusses blood pressure reduction, which has been viewed as a key factor for reducing cardiovascular disease burden in hypertension. Recent analyses from the Blood Pressure Lowering Treatment Trialists’ (BPLTT) Collaboration have highlighted the beneficial effects of blood pressure lowering irrespective of blood pressure levels, age and CV risk profile, thus independently from a diagnosis of hypertension.

Moderated by Weekly Journal Scan Editors Prof. Carlo Patrono and Prof. Massimo Volpe along with Editor-in-Chief Prof. Filippo Crea, this conversation explores the implications of these findings for clinical practice, risk stratification, and future research directions.

In this EHJ Dialogue, Prof. Bernard Gersh discusses his life's journey from Zambia to Rochester USA via South Africa, reflecting on the experiences and influences that have shaped his career in cardiology.

Moderated by Executive Editor Prof. Cecilia Linde and Editor-in-Chief Prof. Filippo Crea, this conversation offers a fascinating insight into his personal and professional milestones, the evolution of cardiovascular medicine, and the lessons learned along the way.

In this EHJ Dialogue, Prof. Marc Pfeffer delves into the PARADISE-MI trial, summarizing its major findings and sharing his personal perspectives on the study results.

Moderated by Weekly Journal Scan Editor Massimo Volpe and Editor-in-Chief Filippo Crea, this conversation offers critical insights into contemporary cardiovascular clinical trials and therapeutic strategies.

In this EHJ Dialogue, Prof. Faiez Zannad discusses the challenges and pitfalls in the interpretation of clinical trials.

Moderated by Associate Editor Prof. Rudolf de Boer and Editor in Chief Prof. Filippo Crea.

In this EHJ Dialogue, Prof. Roxana Mehran explores the critical issues surrounding cardiovascular disease in women, highlighting both the challenges and emerging opportunities for enhanced care. With a focus on specific insights in diagnosis, treatment, and research, she offers expert perspectives aimed at advancing the field of women’s cardiovascular health.

Moderated by Associate Editor Prof. Julinda Mehilli and Editor-in-Chief Prof. Filippo Crea, this conversation provides valuable insights for clinicians and researchers dedicated to improving women's care.

In this EHJ Dialogue, Prof. Colin Baigent discusses individual randomised trials, meta-analyses, and treatment Guidelines.

Moderated by Weekly Journal Scan Editors Profs. Carlo Patrono and Giovanna Liuzzo, and Editor-in-Chief Prof. Filippo Crea, this conversation explores the strengths and limitations of different study designs, the impact of large-scale data on cardiovascular research, and the evolving landscape of evidence-based medicine.

In this EHJ Dialogue, Prof. Ferid Murad discusses the groundbreaking discovery of nitric oxide as a signaling molecule and shares his journey to the Nobel Prize. He reflects on the impact of his research, its clinical implications, and the future of nitric oxide-based therapies in cardiovascular medicine.

Moderated by Executive Editor Prof. Raffaele De Caterina and Editor-in-Chief Prof. Filippo Crea, this conversation offers unique insights into scientific innovation, the challenges and triumphs of pioneering research, and the lasting legacy of nitric oxide in medicine.

In this EHJ Dialogue, Prof. Barbara Casadei reflects on the role and future of scientific societies in the aftermath of COVID-19, discussing the challenges, adaptations, and opportunities that have emerged from the pandemic.

Moderated by Executive Editor Prof. Lina Badimon and Editor-in-Chief Prof. Filippo Crea, this conversation explores the evolving landscape of cardiovascular research, collaboration, and the impact of digital transformation on global scientific communities.

In this EHJ Dialogue, Prof. A. John Camm explores the latest advancements in the understanding and management of arrhythmias, discussing key developments in diagnosis, risk stratification, and treatment strategies.

Moderated by Executive Editor Prof. Robert Hatala and Editor-in-Chief Prof. Filippo Crea, this conversation delves into current challenges, clinical insights, and future directions in arrhythmia research and patient care.

In this EHJ Dialogue, Prof. Christopher Cannon discusses his recent publication on the VERTIS trial, highlighting its key findings and implications for cardiovascular and renal outcomes in patients with diabetes. Joining the discussion is Prof. John Jarcho, Deputy Editor of the New England Journal of Medicine, who provides additional insights into the study’s impact on clinical practice and future research.

Moderated by Weekly Journal Scan Editor Prof. Carlo Patrono and Editor-in-Chief Prof. Filippo Crea, this conversation explores the evolving role of SGLT2 inhibitors, the challenges of translating trial results into real-world practice, and the broader implications for cardiovascular medicine.

In this EHJ Dialogue, Prof. Patrick Serruys reflects on his distinguished career in interventional cardiology, tracing the evolution of the field from pioneering device design to clinical breakthroughs. He shares key insights from decades of research, technological advancements, and the impact of innovation on patient care.

Moderated by Executive Editor Prof. Colin Berry and Editor-in-Chief Prof. Filippo Crea, this conversation explores the milestones, challenges, and future directions of interventional cardiology, offering a unique perspective from one of its leading figures.

In this EHJ Dialogue, Prof. Valentin Fuster navigates the full spectrum of cardiovascular science, from molecular mechanisms to health promotion, offering the perspective of a protagonist.

Moderated by Executive Editor Prof. Lina Badimon and Editor-in-Chief Prof. Filippo Crea, this engaging conversation provides a unique insight into the evolution of the field and the future of cardiovascular health.

In this EHJ Dialogue, Prof. Salim Yusuf explores epidemiology and prevention, offering a bold and thought-provoking global perspective.

Moderated by Executive Editor Anne Tybjærg-Hansen and Editor-in-Chief Prof. Filippo Crea, this discussion examines the challenges and opportunities in shaping the future of cardiovascular health worldwide.

In this EHJ Dialogue, Prof. Milton Packer explores the landscape of heart failure, from its underlying mechanisms to cutting-edge treatments, offering insights into what the future may hold.

Moderated by Executive Editor Prof. Cecilia Linde and Editor-in-Chief Prof. Filippo Crea, this thought-provoking discussion sheds light on the latest advancements and evolving perspectives in the field.

In this EHJ Dialogue, Prof. Eugene Braunwald reflects on the 400-year journey of cardiology, exploring its evolution and milestones.

Moderated by Executive Editor Prof. Peter Libby and Editor-in-Chief Prof. Filippo Crea, this insightful conversation delves into the past, present, and future of the field.