Volume 54, Issue 9, September 2024

The validity of immune-related adverse events as surrogate markers of the efficacy of immune checkpoint inhibitor treatment remains unclear. This review examines the pivotal studies on immune-related adverse events.

Neoadjuvant therapy for breast cancer can cause glucose and lipid metabolism disorder, bone mineral density decrease and muscle reduction, which suggests that patients had an increased chance of developing osteosarcopenia.

The tumor-infiltrating lymphocytes-ultrasonography score is a non-invasive procedure to predict lymphocyte-predominant breast cancers and tumor-infiltrating lymphocytes-ultrasonography score-based nomogram exhibited a favorable predictive ability for pathological complete response in patients with breast cancer.

Sarcopenic obesity was an independent risk factor for short- and long-term outcomes in patients undergoing neoadjuvant chemotherapy for locally advanced gastric cancer.

Serum cholinesterase levels predict skeletal muscle loss after gastrectomy in patients with gastric cancer, suggesting the importance of cholinesterase in postoperative nutritional management.

Elranatamab monotherapy demonstrated clinical efficacy and manageable safety in Japanese patients with relapsed or refractory multiple myeloma, similar to the overall patient population and supporting further studies in Asian populations.

We examined data from 124 employed patients with bone metastases. These patients need support to continue working and to commute and move around in the workplace.

We developed an artificial intelligence model to classify lung adenocarcinoma histologically. Combination of quantification and spatial analysis demonstrated the potential for new uses of histological subtypes.

The highly consistency of PIK3CA mutation status between primary and recurrent tumors suggests that detecting mutations in primary tumors could substitute for analysis of recurrent samples when they are not easily obtainable.

Easily measurable biomarkers are important to identify asymptomatic venous thromboembolism (VTE). A D-dimer level ≥3.3 μg/ml at the time of diagnosis of lung cancer is predictive of coexisting VTE.

We assessed the usefulness of Franseen needle-dedicated endobronchial ultrasound-guided transbronchial needle aspiration and found the Franseen needle tended to show a greater amount of specimen with higher tumor cellularity.

In Japan, radical prostatectomy and radiation therapy have increased as initial treatments for prostate cancer, whereas androgen deprivation therapy has decreased. Radical prostatectomy has become the most selected initial treatment.

A randomized controlled trial to confirm the superiority of new texture and color enhancement imaging than white light imaging in detecting colorectal neoplastic lesions during colonoscopy.