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Journal Article
ACCEPTED MANUSCRIPT
Lu Wang and others
Published: 24 April 2025
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Published: 24 April 2025
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Journal Article
ACCEPTED MANUSCRIPT
Elena Colonnello and others
Published: 19 April 2025
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Published: 19 April 2025
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Published: 03 April 2025
Figure 1. The calcium-sensing receptor (CaSR) signaling in the parathyroid cell. CaSR is a G-coupled protein receptor consisting of an extracellular domain, an intramembrane domain of seven hydrophobic helices, and an intracellular domain. The large extracellular domain interacts with the extracellular ionize
Journal Article
Afroditi Roumpou and others
Published: 03 April 2025
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Published: 03 April 2025
Graphical Abstract Graphical Abstract
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Published: 03 April 2025
Figure 2. Parathyroid hormone (PTH) is a main regulator of calcium and phosphate metabolism. Calcium levels (Ca 2+ ) are tightly controlled through the action of PTH and 1,25(OH) 2 D 3 (calcitriol). Calcium-sensing receptors (CaSRs) are localized on the parathyroid cell membrane and detect changes in the ser
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Published: 03 April 2025
Figure 3. X-ray of the knee joint. Brown tumor of the fibula as a manifestation of primary hyperparathyroidism in a 52-year-old man.
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Published: 03 April 2025
Figure 4. Cascade of events leading to CKD bone and 1,25(OH) 2 D 3 mineral disorder. During the progression of kidney disease, the elevation of FGF23 and PTH fail to decompensate the decreased renal phosphate excretion; thus, serum phosphate rises. Inhibition of 1-a-hydroxylase synthesis of 1,25-(OH) 2 vita
Journal Article
ACCEPTED MANUSCRIPT
Ting Guo and others
Published: 03 April 2025
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Published: 03 April 2025
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Published: 19 March 2025
Figure 1. Sushruta: ∼600 Bce recommended the ingestion of animal testicular tissue for impotence. Shushrut Statue in Patanjali Yogpeeth, Haridwar, https://en.wikipedia.org/wiki/File:Shushrut_statue.jpg .
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Published: 19 March 2025
Figure 3. Advertisement for organ extracts published in The Strand Magazine (London, 1912). The death of Brown-Séquard some years earlier clearly failed to deter speculators from making extravagant claims based on his work.
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Published: 19 March 2025
Figure 4. Criteria used for detecting the effects of testicular extracts on castrated animals. Note here the variability in comb growth at 3 “doses” of an acetone-soluble fraction of bull testes. Bioassay for an androgenic substance: Moore et al ( 165 ). © 1929 by the Endocrine Society.
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Published: 19 March 2025
Figure 5. Carlo Broschi, known as Farinelli. Portrait of the singer Farinelli (Carlo Broschi) (1705-1782). Museum: Royal College of Music London. Author: Bartolomeo Nazari, https://commons.wikimedia.org/wiki/File:Bartolomeo_Nazari_-_Portrait_of_Farinelli_1734_-_Royal_College_of_Music_London.jpg .
Journal Article
Alan D Rogol and Marco Cappa
Published: 19 March 2025
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Published: 19 March 2025
Graphical Abstract Graphical Abstract
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Published: 19 March 2025
Figure 2. Graphical representation of the all or none law. The ordinates correspond to the individual animals and the abscissae to the weight of the tests and length of the comb. There is no parallelism between the weight of the testis and the length of the comb. Segment A-B pertains to cocks showing male cha
Journal Article
Maria Apostolopoulou and others
Published: 25 February 2025