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Published: 04 May 2025
Figure 4. Trajectory Differences in Distal Outcomes at the End of the 2-Year Follow-Up Period Note: (1) All results are statistically significant using a Bonferroni-corrected threshold ( P  < .005). (2) Reference trajectory. CI: Confidence interval, SANS: Scale for the Assessment of Negative Symptoms, S
Journal Article
Olivier Percie du Sert and others
Published: 04 May 2025
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Published: 04 May 2025
Figure 1. Estimated latent trajectories of outcomes over 2-year early intervention services Note: Observed individuals’ trajectories are plotted in the background.
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Published: 04 May 2025
Figure 2. Cross-Distribution of Individuals between (A) Positive Symptoms and Functioning Trajectories, (B) Negative Symptoms and Functioning Trajectories, and (C) Positive and Negative Symptoms Trajectories Note: Each link represents the number of intersecting individuals between the two trajectories it c
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Published: 04 May 2025
Figure 3. Baseline Predictors of Trajectory Membership Note: (1) All results are statistically significant using a Bonferroni-corrected threshold ( P  < .001). (2) Reference trajectory. (3) Log transformed. (4) Binary variable, proportion of cases coded as yes. CI: Confidence interval, OR: Odds ratio, P
Journal Article
Heather M Wastler and others
Published: 28 April 2025
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Published: 28 April 2025
Figure 2. Cross-Level Interaction for Negative Affect and Adaptive/Maladaptive Strategy Use.
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Published: 28 April 2025
Figure 1. Interaction Between Within-Person Emotion Regulation and Between-Person Negative Affect Predicting Concurrent Suicidal Ideation.
Journal Article
Luli Wei and others
Published: 26 April 2025
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Published: 26 April 2025
Figure 1. Correlations between Multimodal MRICIs and Each Symptom Dimension in Schizophrenia. Scatterplots of the Left Panels Depict the Spearman Correlation between Multimodal MRICI Scores and One Symptom Dimension in FE (Dark-Colored) and NFE (Light-Colored) Schizophrenia (Permutation Test, P  < .05, Bo
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Published: 26 April 2025
Figure 2. Correlation between Modality-Specific MRICIs and Each Symptom Dimension in Schizophrenia. Scatterplots Depict the Association between Modality-Specific MRICI Scores and Their Respective Symptom Dimensions in FE (Dark-Colored) and NFE (Light-Colored) Schizophrenia ( P  < .05, Bonferroni Correction
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Published: 26 April 2025
Figure 4. Differences between SZ and HC in MRICIs. (A) The Bar Chart of the Top 3 Panels Represents the Median MRICIs and Their Standard Error (SE) of All, FE, and NFE Cohort, Respectively. Intergroup Comparisons are Performed Using Wilcoxon Rank-Sum Test. ** Represents P  < .05 with Bonferroni Corrected,
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Published: 26 April 2025
Figure 3. Cross-Dimensional Symptom-Brain Correlation, Symptom-Symptom Correlation and Brain-Brain Correlation in Schizophrenia. (A) Spearman Correlations between Symptoms and MRICIs Cross-Dimensions. The circular lines represent correlations, all of which are positive. The line width indicates the strength o
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Published: 26 April 2025
Figure 5. Schizophrenia Subtyping Based on MRICIs. (A) The CH*ARI Values of K -Means as Functions of Number of Subtypes and Clustering Parameters. (B) Leave-One-Site-Out Validation of the Clustering Accuracy. (C) Box Plots of the Intergroup Differences in MRICIs between Subtype-I (Left) and Subtype-II (Right
Journal Article
Emanuel Mlynek and others
Published: 23 April 2025
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Published: 23 April 2025
Figure 1. (A) ROI-to-ROI functional connectivity analysis assessed the association between IL-6 (left) or CRP (right) and the connectivity between the MPFC and different regions related to somato- or viscerosensory processing. SMN = sensorimotor network; ant. = anterior; lat. = lateral; sup. = superior; PO =
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Published: 23 April 2025
Figure 2. Seed-to-voxel functional connectivity analysis of the MPFC. The first row illustrates the definition of the seed. In the second row, the effect of IL-6 on functional connectivity is presented: a cluster of hypo-connectivity emerged in the right hemisphere encompassing the parietal operculum and audi
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Published: 23 April 2025
Figure 3. Structural and behavioral correlates of disturbed functional connectivity between the medial prefrontal cortex (MPFC) and the right parietal opercular cortex (PO r). (A) Visualization of fibers tracked between the two seeds from a representative patient using probabilistic fiber tracking. (B) Scatte
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Published: 18 April 2025
Figure 3. Effects of LIPUS stimulation on the expressions of 5-HT1AR and 5-HT2AR in the medial prefrontal cortex (mPFC) of MK-801-treated rats. (A) Representative images showing 5-HT1AR-positive cells (first column) and NeuN-positive cells (second column) in the mPFC. Arrows point to cells co-labeled for 5-HT
Journal Article
Feng-Yi Yang and others
Published: 18 April 2025