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Introduction Kidney transplant recipients are among the populations at risk for Hepatitis B Virus (HBV) reactivation, and close monitoring is needed for its early detection. Methods We describe a case of HBV reactivation in a patient who underwent kidney transplantation more than 30 years ago, with ...
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The steps that initiate coagulation in vivo are different from the components of prothrombin time (PT) and activated partial thromboplastin time (aPTT). The reactions of PT and aPTT are kept separate by the addition of high concentrations of tissue factor (for PT) or silica (for aPTT). In vivo, ...
Introduction Kidney transplant recipients are among the populations at risk for Hepatitis B Virus (HBV) reactivation, and close monitoring is needed for its early detection. Methods We describe a case of HBV reactivation in a patient who underwent kidney transplantation more than 30 years ago, with ...
Introduction Human epididymis protein 4 (HE4), a potential novel biomarker for cancers, has been widely used in clinical practice, but evidence of its prognostic value for non–small cell lung cancer (NSCLC) remain insufficient. This study aimed to explore the predictive value of serum HE4 levels on ...
Introduction Iron-deficiency anemia (IDA) and non–transfusion-dependent thalassemia (NTDT) are the 2 most common types of microcytic hypochromic anemia, but they are difficult to distinguish by routine tests. It is reported that red blood cells (RBCs) in thalassemia tend to be more microcytic and ...
Introduction Coronary artery disease (CAD) is a prevalent inflammatory disease. Interferon λ 1 (IFN-λ1) is a known factor that participates in the pathogenesis of proinflammatory diseases, but the roles of IFN-λ1 in CAD and its regulators have yet to be clarified. Bioinformatic analysis revealed ...
Introduction Discrepancies in gel card immunohematologic testing can result in false-positive reactions, making detecting antibodies and performing crossmatching difficult. Such unexpected reactivity may result from interactions with test system components, including the column matrix, chemicals, ...
Introduction Pseudoachondroplasia is a rare and severe genetic disorder caused by a mutation in the COMP gene, making precise molecular diagnosis crucial for effective treatment. In the literature, case reports of patients with pseudoachondroplasia have consistently described novel mutations in the ...
Introduction The Clinical Laboratory Improvement Amendments require nonconforming safety event identification, targeted intervention, and evaluation of interventional effectiveness. Without a standardized reporting structure, risk and safety teams will experience ongoing challenges with situational ...
Introduction Duchenne muscular dystrophy (DMD) is a severe genetic disorder affecting 5% to 19% of carriers. Creatine kinase (CK) is a traditional biomarker for DMD, but its screening accuracy is limited. This study evaluated the potential of combining the proto-oncogene tyrosine-protein kinase ...
Introduction We sought to compare clinical features among distinct antibody profiles defined by the presence or absence of antinucleosome (anti-NCS) and anti–double-stranded DNA (anti-dsDNA) antibodies in Tunisian patients with systemic lupus erythematosus (SLE). Methods The study enrolled 131 ...
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Roger L. Bertholf, PhD
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